OSCR

Interhemispheric CA1 projections to the subiculum support spatial cognition and are affected in a mouse model of the 22q11.2 deletion syndrome.

Overview

Authors: Noelia S de León Reyes1,2, Maria Helena Bortolozzo-Gleich1, Helden Natalia Velez Gonzalez1, Yuki Nomura1, Cristina García Frigola1, Marta Nieto2, Joseph A Gogos3,4,5,6,7, Félix Leroy1
  1. Instituto de Neurociencias CSIC-UMH, Avenida Santiago Ramon y Cajal San Juan de Alicante, Alicante, Spain
  2. Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus de Cantoblanco, Darwin 3, 28049 Madrid, Spain
  3. Department of Neuroscience, Columbia University, New York, NY, USA
  4. Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA
  5. Department of Physiology, Columbia University, New York, NY, USA
  6. Department of Psychiatry, Columbia University, New York, NY, USA
  7. Stavros Niarchos Foundation Center for Precision Psychiatry and Mental Health, Columbia University, New York, NY, USA
Journal: Cell reports, volume 45, issue 4, article 117114
Dates: received 14 March 2025; accepted 19 February 2026; published online 20 March 2026; in print March 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.celrep.2026.117114 · PMID 41863797 · PMCID PMC13125397 · OpenAlex W7139948513
Open access: gold, a free copy (OpenAlex)
Status: code on request (how the code is found and verified)
Categories: mouse (organism), schizophrenia / psychosis (population), cognitive (subfield)
Methods: Evoked potentials, fMRI & imaging
Keywords: spatial cognition, 22q11.2 deletion syndrome, schizophrenia, subiculum, inter-hemispheric
Topic: Congenital heart defects research (Molecular Biology, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Funding: GVA; European Research Council; National Institute of Mental Health and Neurosciences
Citations: not cited yet (Europe PMC); 96 references in the paper
Research resources: Anti-GFP antibody produced in chicken RRID:AB_10000240, RRID:AB_10563566, RRID:AB_142924, Anti-RFP antibody produced in rabbit RRID:AB_2209751, RRID:AB_221569, RRID:AB_2576217, C57BL/6J Mus musculus RRID:IMSR_JAX:000664

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper says that its authors' code is available on request: it was not published with the paper, so there is nothing to verify.

The paper's code and data availability statement is in the Data section.

Tracing map

A tracing map links a paper to the code its authors published: this paper has none (its code is available on request), so it has no map.

Data

No dataset and no data link were found in the paper.

Code and data availability statement

The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the data are available on request
  • it says that the code is available on request

Read it in the paper: doi.org/10.1016/j.celrep.2026.117114.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 8 authors, 5 keywords, 3 funders, 95 references, 7 RRIDs.

Cite

This paper

de León Reyes, N. S., Bortolozzo-Gleich, M. H., Velez Gonzalez, H. N., Nomura, Y., Frigola, C. G., Nieto, M., Gogos, J. A., & Leroy, F. (2026). Interhemispheric CA1 projections to the subiculum support spatial cognition and are affected in a mouse model of the 22q11.2 deletion syndrome. Cell reports, 45(4), 117114. https://doi.org/10.1016/j.celrep.2026.117114

BibTeX

@article{deleonreyes2026interhemispheric,
author = {de León Reyes, Noelia S and Bortolozzo-Gleich, Maria Helena and Velez Gonzalez, Helden Natalia and Nomura, Yuki and Frigola, Cristina García and Nieto, Marta and Gogos, Joseph A and Leroy, Félix},
title = {{Interhemispheric CA1 projections to the subiculum support spatial cognition and are affected in a mouse model of the 22q11.2 deletion syndrome}},
journal = {Cell reports},
year = {2026},
month = mar,
volume = {45},
number = {4},
pages = {117114},
publisher = {Cell Press},
issn = {2211-1247},
doi = {10.1016/j.celrep.2026.117114},
url = {https://doi.org/10.1016/j.celrep.2026.117114},
pmid = {41863797},
pmcid = {PMC13125397}
}

RIS

TY - JOUR
AU - de León Reyes, Noelia S
AU - Bortolozzo-Gleich, Maria Helena
AU - Velez Gonzalez, Helden Natalia
AU - Nomura, Yuki
AU - Frigola, Cristina García
AU - Nieto, Marta
AU - Gogos, Joseph A
AU - Leroy, Félix
TI - Interhemispheric CA1 projections to the subiculum support spatial cognition and are affected in a mouse model of the 22q11.2 deletion syndrome
T2 - Cell reports
J2 - Cell Rep
PY - 2026
DA - 2026/03/20
VL - 45
IS - 4
SP - 117114
SN - 2211-1247
PB - Cell Press
DO - 10.1016/j.celrep.2026.117114
UR - https://doi.org/10.1016/j.celrep.2026.117114
LA - en
ER -

CSL-JSON

{
"id": "10.1016/j.celrep.2026.117114",
"type": "article-journal",
"title": "Interhemispheric CA1 projections to the subiculum support spatial cognition and are affected in a mouse model of the 22q11.2 deletion syndrome",
"container-title": "Cell reports",
"author": [
{
"family": "de León Reyes",
"given": "Noelia S"
},
{
"family": "Bortolozzo-Gleich",
"given": "Maria Helena"
},
{
"family": "Velez Gonzalez",
"given": "Helden Natalia"
},
{
"family": "Nomura",
"given": "Yuki"
},
{
"family": "Frigola",
"given": "Cristina García"
},
{
"family": "Nieto",
"given": "Marta"
},
{
"family": "Gogos",
"given": "Joseph A"
},
{
"family": "Leroy",
"given": "Félix"
}
],
"container-title-short": "Cell Rep",
"volume": "45",
"issue": "4",
"page": "117114",
"DOI": "10.1016/j.celrep.2026.117114",
"PMID": "41863797",
"PMCID": "PMC13125397",
"ISSN": "2211-1247",
"publisher": "Cell Press",
"URL": "https://doi.org/10.1016/j.celrep.2026.117114",
"language": "en",
"issued": {
"date-parts": [
[
2026,
3,
20
]
]
}
}

Similar papers

The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.

[1] doi:10.1186/s13041-026-01300-7
Hippocampal transcriptome profiling in a 22q11.2 deletion syndrome mouse model: comparison with human schizophrenia.
Journal: Molecular brain
In common: schizophrenia / psychosis, mouse, 8 references
[2] doi:10.1038/s41467-025-61994-6 [code]
Impaired vasopressin neuromodulation of the lateral septum leads to social behavior deficits in Shank3B<sup>+/-</sup> male mice.
Journal: Nature communications
In common: mouse, 2 references, 2 authors
[3] doi:10.1038/s41398-026-04108-0 [code]
Divergent transcriptomic pathways underlie sex-biased cognitive rescue by developmental GSK3B inhibition in a mouse model of 22q11.2 deletion syndrome.
Journal: Translational psychiatry
In common: schizophrenia / psychosis, mouse, 7 references
[4] doi:10.1038/s41467-022-34039-5 [code]
Hemisphere-specific spatial representation by hippocampal granule cells.
Journal: Nature communications
In common: mouse, 6 references
[5] doi:10.1038/s41467-026-72275-1 [code]
Distinct CA3 inputs differentially shape the learning-dependent evolution of right CA1 spatial maps.
Journal: Nature communications
In common: mouse, 6 references
[6] doi:10.1038/s41467-022-31073-1 [code]
An in vitro model of neuronal ensembles.
Journal: Nature communications
In common: schizophrenia / psychosis, 5 references
[7] doi:10.1038/s41467-023-42964-2 [code]
Altered corollary discharge signaling in the auditory cortex of a mouse model of schizophrenia predisposition.
Journal: Nature communications
In common: schizophrenia / psychosis, mouse, 4 references
[8] doi:10.1186/s13293-026-00885-x [code]
A transient sex-biased transcriptional program shapes early postnatal L2/3 neuron development.
Journal: Biology of sex differences
In common: mouse, 1 reference, author Marta Nieto
[9] doi:10.1038/s42003-022-03692-3
Multimodal anatomy of the human forniceal commissure.
Journal: Communications biology
In common: 4 references
[10] doi:10.1038/s41467-025-62187-x [code]
Aberrant pace of cortical neuron development in brain organoids from patients with 22q11.2 deletion syndrome-associated schizophrenia.
Journal: Nature communications
In common: schizophrenia / psychosis, 4 references

Contribute

The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.

Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.

Request its removal

To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).

Discussion, reproductions, activity

Discussion: code errors and mismatches between the code and the paper about this paper and its code, from readers and its authors, beside the paper and its tracing map.

Reproductions: reports from readers who ran the authors' code and did not get the paper's result, what they ran, with which environment, commit and data.

Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.