Female metabolic resilience and male-biased protein quality defects under hypoxia in human brain organoids.
Overview
- Paris Saclay University, CEA, INRAE, DMTS, SPI, Neurovascular Research Unit & Therapeutic Innovation Laboratory, Gif-sur-Yvette 91190, France
- Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates
- BIMAI-Lab, Biomedically Informed Artificial Intelligence Laboratory, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates
- Skolkovo Institute of Science and Technology, Moscow, Russia
- Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest 1117, Hungary
- Université Paris-Saclay, CEA DMTS, INRAE, SPI, 30200 Bagnols-sur-Cèze, France
- Center of Excellence for Precision Medicine, Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates
- Division of Surgery and Interventional Science, University College London, London NW3 2PF UK
Abstract
The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.
Code
The paper says that its authors' code is available on request: it was not published with the paper, so there is nothing to verify.
The paper's code and data availability statement is in the Data section.
Tracing map
A tracing map links a paper to the code its authors published: this paper has none (its code is available on request), so it has no map.
Data
Datasets cited
- data.mendeley.com/
datasets/ , at Mendeley Data; found in the text, “Statistical analysis”9m8zzmdbb9 - zenodo:17993221, at Zenodo; found in “Data and code availability”
Code and data availability statement
The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:
- it points to a dataset: Zenodo 17993221
- it says that the data are available on request
- it says that the code is available on request
Read it in the paper: doi.org/10.1016/j.isci.2026.115714.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 1, 29 September 2026: the first record
Recorded: type, language, journal, volume, issue, pages, dates, 12 authors, 1 keyword, 2 funders, 66 references, 8 RRIDs.
Cite
This paper
Gaston-Breton, R., Bouzid, A., Antipushina, E., Costa, N., Sarkadi, B., Apati, A., Harati, R., Sharaev, M., Armengaud, J., Disdier, C., Hamoudi, R., & Mabondzo, A. (2026). Female metabolic resilience and male-biased protein quality defects under hypoxia in human brain organoids. iScience, 29(5), 115714. https://
BibTeX
@article{gastonbreton202
author = {Gaston-Breton, Romane and Bouzid, Amal and Antipushina, Ekaterina and Costa, Narciso and Sarkadi, Balazs and Apati, Agota and Harati, Rania and Sharaev, Maxim and Armengaud, Jean and Disdier, Clémence and Hamoudi, Rifat and Mabondzo, Aloïse},
title = {{Female metabolic resilience and male-biased protein quality defects under hypoxia in human brain organoids}},
journal = {iScience},
year = {2026},
month = apr,
volume = {29},
number = {5},
pages = {115714},
publisher = {Elsevier},
issn = {2589-0042},
doi = {10.1016/
url = {https://
pmid = {42111172},
pmcid = {PMC13157167}
}
RIS
TY - JOUR
AU - Gaston-Breton, Romane
AU - Bouzid, Amal
AU - Antipushina, Ekaterina
AU - Costa, Narciso
AU - Sarkadi, Balazs
AU - Apati, Agota
AU - Harati, Rania
AU - Sharaev, Maxim
AU - Armengaud, Jean
AU - Disdier, Clémence
AU - Hamoudi, Rifat
AU - Mabondzo, Aloïse
TI - Female metabolic resilience and male-biased protein quality defects under hypoxia in human brain organoids
T2 - iScience
J2 - iScience
PY - 2026
DA - 2026/
VL - 29
IS - 5
SP - 115714
SN - 2589-0042
PB - Elsevier
DO - 10.1016/
UR - https://
LA - en
ER -
CSL-JSON
{
"id": "10.1016/
"type": "article-journal",
"title": "Female metabolic resilience and male-biased protein quality defects under hypoxia in human brain organoids",
"container-title": "iScience",
"author": [
{
"family": "Gaston-Breton",
"given": "Romane"
},
{
"family": "Bouzid",
"given": "Amal"
},
{
"family": "Antipushina",
"given": "Ekaterina"
},
{
"family": "Costa",
"given": "Narciso"
},
{
"family": "Sarkadi",
"given": "Balazs"
},
{
"family": "Apati",
"given": "Agota"
},
{
"family": "Harati",
"given": "Rania"
},
{
"family": "Sharaev",
"given": "Maxim"
},
{
"family": "Armengaud",
"given": "Jean"
},
{
"family": "Disdier",
"given": "Clémence"
},
{
"family": "Hamoudi",
"given": "Rifat"
},
{
"family": "Mabondzo",
"given": "Aloïse"
}
],
"container-title-short":
"volume": "29",
"issue": "5",
"page": "115714",
"DOI": "10.1016/
"PMID": "42111172",
"PMCID": "PMC13157167",
"ISSN": "2589-0042",
"publisher": "Elsevier",
"URL": "https://
"language": "en",
"issued": {
"date-parts": [
[
2026,
4,
11
]
]
}
}
Similar papers
The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.
- [1] doi:10.1002/adhm.202504889 [code]
- Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience.Journal: Advanced healthcare materialsIn common: 2 references
- [2] doi:10.3390/ijms27114920
- Timing-Dependent Effects of Dexamethasone in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury: A Transcriptomic Analysis of Synaptic Signaling and Calcium Homeostasis.Journal: International journal of molecular sciencesIn common: 2 references
- [3] doi:10.3389/fnsys.2026.1753562
- When the gatekeeper falls: developmental vulnerability of the thalamic reticular nucleus in neonatal and pediatric hypoxic-ischemic brain injury.Journal: Frontiers in systems neuroscienceIn common: 2 references
- [4] doi:10.1111/joa.70225
- Immune proteomic associations with indices of cortical development in 5-year-old children.Journal: Journal of anatomyIn common: 1 reference
- [5] doi:10.1242/dmm.052747 [code]
- Cell death analysis of inducible, titratable neurodegenerative disease models in zebrafish and human stem cell-derived retinal organoids.Journal: Disease models & mechanismsIn common: 1 reference
- [6] doi:10.1038/s41467-026-74274-8 [code]
- Regional sex differences in human cortical anatomy vary in their morphometric bases and overlap with sex chromosomal and gonadal influences.Journal: Nature communicationsIn common: 1 reference
- [7] doi: [code]
- Developing and Validating a Machine Learning Model to Predict Brain Injury in Preterm Infants Using Multisource Data from the Early Postnatal PeriodJournal: Children (Basel, Switzerland)In common: 1 reference
- [8] doi:10.34133/csbj.0083
- The Role of Astrocyte-Neuron Interactions in Shaping Neuronal Maturation during Human Brain Development.Journal: Computational and structural biotechnology journalIn common: 1 reference
- [9] doi:10.1186/s13024-026-00944-2
- TDP-43: [GU]-ardian of the transcriptome.Journal: Molecular neurodegenerationIn common: 1 reference
- [10] doi:10.1111/joa.70170 [code]
- A posttranslational proteomic survey of a single anatomically preserved human 20-week postconception brain.Journal: Journal of anatomyIn common: 1 reference
Contribute
The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.
Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.
Claim this paper
Correct its record
Say what each link of this record is, remove the ones that are not the paper's, add the ones that are missing. The correction becomes a new version of the record, in its Versions section.
Request its removal
To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).
Discussion, reproductions, activity
Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.
Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.
Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.
