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Periostin drives psoriasis progression through the stimulation of cutaneous nerve fibers.

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Paper

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The authors' code

R · 15 lines · 521 B · no license

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Overview

Authors: Caiwei Zhuang1,2,3,4, Qiulin Dong1,2,3,4, Minjie Liu1,2,3,4, Ying Tuo5, Peishan Chen3,4, Jiaying Li3,4, Si Liu3,4, Renchu Liu3,4, Xuzhuo Cheng3,4, Ruiyang Li3,4, Sheng Wang3,4, Shiyun Huang3,4, Yufeng Liu6,7, Rui Zhang3,4, Andy Peng Xiang3,4, Ge Shi6,8,7, Mei Hua Jiang1,2,3,4
ORCID iDs: Mei Hua Jiang
  1. Program of Stem Cells and Regenerative Medicine, Affiliated Guangzhou Women and Children’s Medical Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
  2. Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
  3. Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China
  4. National-Local Joint Engineering Research Center for Stem Cells and Regenerative Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
  5. Department of Pathology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
  6. Biomedical Innovation Center and Department of Cosmetic and Plastic Surgery, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
  7. Biomedical Innovation Center, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
  8. Key Laboratory of Human Microbiome and Chronic Diseases, Sun Yat-sen University, Ministry of Education, Guangzhou, China
Institutions: Sun Yat-sen University (China); Guangzhou Women and Children Medical Center (China); The First Affiliated Hospital, Sun Yat-sen University (China); Sixth Affiliated Hospital of Sun Yat-sen University (China)
Journal: iScience, volume 29, issue 8, article 116021
Dates: received 15 November 2025; accepted 31 March 2026; published online 11 August 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.isci.2026.116021 · PMID 42621185 · PMCID PMC13486832 · OpenAlex W7202181787
Open access: gold, a free copy (OpenAlex)
Status: code verified
Categories: mouse (organism)
Methods: Statistics, Smoothing, state filtering, decompositions, fMRI & imaging
Keywords: psoriasis, periostin, skin nerve fiber, dorsal root ganglion, neuronal axonal growth
Topic: Psoriasis: Treatment and Pathogenesis (Immunology, Immunology and Microbiology), according to OpenAlex
Funding: Basic and Applied Basic Research Foundation of Guangdong Province (2023B1515120032); National Natural Science Foundation of China (31972894); Foundation for Innovative Research Groups of the National Natural Science Foundation of China; Key Technologies Research and Development Program of Guangzhou (202206060003)
Citations: not cited yet (Europe PMC); 84 references in the paper
Research resources: Anti-GAPDH RRID:AB_10622025, Anti-PGP9.5 RRID:AB_10891773, Anti-Nav1.8 RRID:AB_2040188, Anti-mTOR RRID:AB_2105622, Anti-beta III Tubulin RRID:AB_2256751, Anti-Phospho-mTOR RRID:AB_2262884, Anti-TRPV1 RRID:AB_2313819, Anti-Phospho-Akt RRID:AB_2315049, anti-Keratin 14 RRID:AB_2616962, Anti-Ki67 RRID:AB_2687446, Anti-CGRP RRID:AB_2798662, Anti-Phospho-PI3-kinase p85- alpha/gamma RRID:AB_2936325, Anti-PI3 kinase p85 alpha RRID:AB_3665436, Anti-Periostin RRID:AB_3716410, Anti-Ki67 RRID:AB_443209, Anti-Akt RRID:AB_915783, Mouse: B6;129-Postntm1Jmol/J RRID:IMSR_JAX:009067

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Repository

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immunogenomics/harmony

License: none: the authors keep all their rights
State: the link answers, verified on 27 September 2026
Evidence: files inventoried
Commit: df19af23ae0639bd6ea2da63898f973f08c85862, 5 June 2026
Languages: R (22), C/C++ (5), C++ (4)
Size: 69 files, 31 scripts
Software Heritage: archived
Found in: the text, “scRNA-seq data processing, quality control, and ”
Holds: README, environment (DESCRIPTION), tests, continuous integration, documentation, 7 notebooks
Not found: license file, CITATION.cff
Tools: Harmony (14 files), tidyverse (10 files), cowplot (7 files), ggplot2 (6 files), Seurat (4 files), data.table (3 files), patchwork (3 files), SingleCellExperiment (1 file)
Availability: 1 check, the latest on 27 September 2026: the link answers
  • 27 September 2026: the link answers
32 files, not copied: shown from their source

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At the source: github.com/immunogenomics/harmony

The paper's code and data availability statement is in the Data section.

Tracing map

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  • 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
  • 31 scripts, each with its path and the digest of its content;
  • no match between paragraphs and code yet;
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Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

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Other data links

Availability statements

The paper has a data availability statement and a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing them here; in short, from what the harvester recognized in them:

  • they point to 2 datasets: NCBI, NCBI GEO GSE300908
  • they say that the data are available on request
  • they say that the code is available on request

Read them in the paper: doi.org/10.1016/j.isci.2026.116021.

Versions

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Version 3, 28 September 2026

  • Authors: added Mei Hua Jiang (0000-0001-9238-386X); removed Mei Hua Jiang

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 17 authors, 5 keywords, 4 funders, 84 references, 17 RRIDs.

Cite

This paper

Zhuang, C., Dong, Q., Liu, M., Tuo, Y., Chen, P., Li, J., Liu, S., Liu, R., Cheng, X., Li, R., Wang, S., Huang, S., Liu, Y., Zhang, R., Xiang, A. P., Shi, G., & Jiang, M. H. (2026). Periostin drives psoriasis progression through the stimulation of cutaneous nerve fibers. iScience, 29(8), 116021. https://doi.org/10.1016/j.isci.2026.116021

BibTeX

@article{zhuang2026periostin,
author = {Zhuang, Caiwei and Dong, Qiulin and Liu, Minjie and Tuo, Ying and Chen, Peishan and Li, Jiaying and Liu, Si and Liu, Renchu and Cheng, Xuzhuo and Li, Ruiyang and Wang, Sheng and Huang, Shiyun and Liu, Yufeng and Zhang, Rui and Xiang, Andy Peng and Shi, Ge and Jiang, Mei Hua},
title = {{Periostin drives psoriasis progression through the stimulation of cutaneous nerve fibers}},
journal = {iScience},
year = {2026},
month = aug,
volume = {29},
number = {8},
pages = {116021},
publisher = {Elsevier},
issn = {2589-0042},
doi = {10.1016/j.isci.2026.116021},
url = {https://doi.org/10.1016/j.isci.2026.116021},
pmid = {42621185},
pmcid = {PMC13486832}
}

RIS

TY - JOUR
AU - Zhuang, Caiwei
AU - Dong, Qiulin
AU - Liu, Minjie
AU - Tuo, Ying
AU - Chen, Peishan
AU - Li, Jiaying
AU - Liu, Si
AU - Liu, Renchu
AU - Cheng, Xuzhuo
AU - Li, Ruiyang
AU - Wang, Sheng
AU - Huang, Shiyun
AU - Liu, Yufeng
AU - Zhang, Rui
AU - Xiang, Andy Peng
AU - Shi, Ge
AU - Jiang, Mei Hua
TI - Periostin drives psoriasis progression through the stimulation of cutaneous nerve fibers
T2 - iScience
J2 - iScience
PY - 2026
DA - 2026/08/11
VL - 29
IS - 8
SP - 116021
SN - 2589-0042
PB - Elsevier
DO - 10.1016/j.isci.2026.116021
UR - https://doi.org/10.1016/j.isci.2026.116021
LA - en
ER -

CSL-JSON

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