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The deficiency of KIF2C leads to abnormal distribution of cortical neurons and behavioral deficits in mice.

Overview

Authors: Shuyi Liu1, Liping Shi1, Liuyi Yu1, Yuan Deng1, Qihang Chen1, Linhua Jiang1, Shaoxing Dai1,2, Shangang Li3, Zhengbo Wang1,2
ORCID iDs: Zhengbo Wang
  1. State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan, China
  2. Yunnan Key Laboratory of Primate Biomedical Research, Kunming, Yunnan, China
  3. State Key Laboratory of Cardiovascular Diseases and Medical Innovation Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China
Journal: iScience, volume 29, issue 8, article 117069
Dates: received 18 March 2026; accepted 20 July 2026; published online 6 August 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.isci.2026.117069 · PMID 42602724 · PMCID PMC13475690 · OpenAlex W7196957503
Open access: gold, a free copy (OpenAlex)
Status: code on request
Categories: mouse (organism)
Methods: Statistics, Smoothing, state filtering, decompositions
Keywords: Kif2C, deep-layer cortical neurons, excitatory-inhibitory balance, microtubule dynamics, neurodevelopment pathway
Topic: Microtubule and mitosis dynamics (Cell Biology, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Funding: Yunnan Provincial Natural Science Foundation (202401AS070086); National Natural Science Foundation of China (82571435); National Key Research and Development Program of China (2023YFA1801802)
Citations: not cited yet (Europe PMC); 52 references in the paper
Research resources: RRID:AB_10561522, Rabbit polyclonal Anti-NeuN RRID:AB_11204707, RRID:AB_142057, RRID:AB_143165, Rat monoclonal Anti-Ctip2 RRID:AB_2064130, Rabbit monoclonal Anti-CUX1 RRID:AB_2086995, Mouse monoclonal Anti-GAPDH RRID:AB_2107436, Rabbit monoclonal Anti-TBR1 RRID:AB_2200219, RRID:AB_2256751, RRID:AB_228307, Rabbit polyclonal Anti-beta-actin RRID:AB_2305186, RRID:AB_2650601, Rabbit polyclonal Anti-VGLUT 1 RRID:AB_2744598, Rabbit polyclonal Anti-KIF2C RRID:AB_2877829, Mouse monoclonal Anti-Calbindin RRID:AB_2888488

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Code and data availability statement

The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

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Read it in the paper: doi.org/10.1016/j.isci.2026.117069.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 3, 28 September 2026

  • Authors: added Zhengbo Wang (0000-0002-4717-5137); removed Zhengbo Wang

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 9 authors, 5 keywords, 3 funders, 52 references, 15 RRIDs.

Cite

This paper

Liu, S., Shi, L., Yu, L., Deng, Y., Chen, Q., Jiang, L., Dai, S., Li, S., & Wang, Z. (2026). The deficiency of KIF2C leads to abnormal distribution of cortical neurons and behavioral deficits in mice. iScience, 29(8), 117069. https://doi.org/10.1016/j.isci.2026.117069

BibTeX

@article{liu2026deficiency,
author = {Liu, Shuyi and Shi, Liping and Yu, Liuyi and Deng, Yuan and Chen, Qihang and Jiang, Linhua and Dai, Shaoxing and Li, Shangang and Wang, Zhengbo},
title = {{The deficiency of KIF2C leads to abnormal distribution of cortical neurons and behavioral deficits in mice}},
journal = {iScience},
year = {2026},
month = aug,
volume = {29},
number = {8},
pages = {117069},
publisher = {Elsevier},
issn = {2589-0042},
doi = {10.1016/j.isci.2026.117069},
url = {https://doi.org/10.1016/j.isci.2026.117069},
pmid = {42602724},
pmcid = {PMC13475690}
}

RIS

TY - JOUR
AU - Liu, Shuyi
AU - Shi, Liping
AU - Yu, Liuyi
AU - Deng, Yuan
AU - Chen, Qihang
AU - Jiang, Linhua
AU - Dai, Shaoxing
AU - Li, Shangang
AU - Wang, Zhengbo
TI - The deficiency of KIF2C leads to abnormal distribution of cortical neurons and behavioral deficits in mice
T2 - iScience
J2 - iScience
PY - 2026
DA - 2026/08/06
VL - 29
IS - 8
SP - 117069
SN - 2589-0042
PB - Elsevier
DO - 10.1016/j.isci.2026.117069
UR - https://doi.org/10.1016/j.isci.2026.117069
LA - en
ER -

CSL-JSON

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