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Electron transport chain complex I and mitochondrial fusion regulate ROS for differentiation in Drosophila neural stem cells.

Overview

Authors: Rahul Kumar Verma1, Atharva Bhingare1, Dnyanesh Dubal1, Richa Rikhy1
ORCID iDs: Richa Rikhy
  1. Biology, Indian Institute of Science Education and Research, Homi Bhabha Road, Pashan, Pune 411008, India
Institutions: Indian Institute of Science Education and Research Pune (India)
Journal: Stem cell reports, volume 21, issue 7, article 102951
Dates: received 9 August 2025; accepted 8 May 2026; published online 11 June 2026; in print July 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.stemcr.2026.102951 · PMID 42276058 · PMCID PMC13385725 · OpenAlex W7164365062
Open access: gold, a free copy (OpenAlex)
Status: code on request
Categories: drosophila (organism)
Methods: Preprocessing, Statistics, Evoked potentials, fMRI & imaging
Keywords: mitochondria, neural stem cells, neuroblasts, Drp1, complex I, differentiation, mitochondrial fusion, mitochondrial fragmentation, Drosophila, Notch
MeSH: Cell Differentiation*, Drosophila melanogaster*, Electron Transport Complex I*, Mitochondrial Dynamics*, Neural Stem Cells*, Reactive Oxygen Species*, Animals, Cell Lineage, Cell Proliferation, Cyclin E, Cytoskeletal Proteins, Drosophila, Drosophila Proteins, GTP-Binding Proteins, Membrane Potential, Mitochondrial, Mitochondria, Receptors, Notch, Signal Transduction (* major topic)
Topic: Mitochondrial Function and Pathology (Molecular Biology, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Funding: Wellcome Trust DBT India Alliance (India Alliance) (IA/S/22/1/506232); CSIR
Citations: not cited yet (Europe PMC); 67 references in the paper
Research resources: RRID:AB_10984484, RRID:AB_141373, RRID:AB_141778, RRID:AB_141874, RRID:AB_142924, RRID:AB_143157, RRID:AB_143165, RRID:AB_2341188, Chicken polyclonal anti-GFP (1:1000) RRID:AB_2534023, RRID:AB_2534072, RRID:AB_2535804, RRID:AB_2535813, Rat monoclonal anti-Deadpan (1:150) RRID:AB_2687586, Rat monoclonal anti-Miranda (1:400) RRID:AB_2936368, RRID:AB_301438, RRID:AB_331250, RRID:AB_528410, Mouse monoclonal anti-Prospero (1:20) RRID:AB_528440, RRID:AB_627262, RRID:AB_638863, D.melanogaster; UAS-SOD2.M RRID:BDSC_24494, RRID:BDSC_25969, RRID:BDSC_29534, RRID:BDSC_29592, RRID:BDSC_31595, RRID:BDSC_34526, RRID:BDSC_34616, D.melanogaster; UAS-mCherry-RNAi RRID:BDSC_35785, RRID:BDSC_36701, D. melanogaster; mhc-Gal4 RRID:BDSC_38464, RRID:BDSC_50577, RRID:BDSC_52922, RRID:BDSC_57499, D.melanogaster; UAS-bsk.DN RRID:BDSC_6409, D.melanogaster; UAS-mito-HA-GFP.AP RRID:BDSC_8442, D.melanogaster; UAS-hep.B RRID:BDSC_9308

Abstract

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Read it in the paper: doi.org/10.1016/j.stemcr.2026.102951.

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Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 4 authors, 10 keywords, 18 MeSH terms, 2 funders, 67 references, 36 RRIDs.

Cite

This paper

Verma, R. K., Bhingare, A., Dubal, D., & Rikhy, R. (2026). Electron transport chain complex I and mitochondrial fusion regulate ROS for differentiation in Drosophila neural stem cells. Stem cell reports, 21(7), 102951. https://doi.org/10.1016/j.stemcr.2026.102951

BibTeX

@article{verma2026electron,
author = {Verma, Rahul Kumar and Bhingare, Atharva and Dubal, Dnyanesh and Rikhy, Richa},
title = {{Electron transport chain complex I and mitochondrial fusion regulate ROS for differentiation in Drosophila neural stem cells}},
journal = {Stem cell reports},
year = {2026},
month = jun,
volume = {21},
number = {7},
pages = {102951},
publisher = {Elsevier},
issn = {2213-6711},
doi = {10.1016/j.stemcr.2026.102951},
url = {https://doi.org/10.1016/j.stemcr.2026.102951},
pmid = {42276058},
pmcid = {PMC13385725}
}

RIS

TY - JOUR
AU - Verma, Rahul Kumar
AU - Bhingare, Atharva
AU - Dubal, Dnyanesh
AU - Rikhy, Richa
TI - Electron transport chain complex I and mitochondrial fusion regulate ROS for differentiation in Drosophila neural stem cells
T2 - Stem cell reports
J2 - Stem Cell Reports
PY - 2026
DA - 2026/06/11
VL - 21
IS - 7
SP - 102951
SN - 2213-6711
PB - Elsevier
DO - 10.1016/j.stemcr.2026.102951
UR - https://doi.org/10.1016/j.stemcr.2026.102951
LA - en
ER -

CSL-JSON

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