Associations of social isolation and loneliness with neurological disorders, psychiatric disorders, brain structures and behavioural phenotypes among UK Biobank participants.
Paper
Loaded from Europe PMC by your browser, not stored by OSCR: doi.org · Europe PMC
The paper is loaded when this pane is shown.
The authors' code
Markdown · 1 line · 122 B · no license
- Code for "Social isolation and loneliness are associated 11 neurological and psychiatric disorders in UK Biobank cohort".
README.md at commit 10770d8, no license · at the source
Overview
- Department of Neurology, Qingdao Municipal Hospital, Qingdao University,Qingdao, China
- Department of Neurology and Institute of Neurology, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontier Center for Brain Science, Shanghai Medical College, Fudan University,Shanghai, China
- Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University,Shanghai, China
- Department of Computer Science, University of Warwick,Coventry, UK
Abstract
The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.
Repositories
Its files are read in the Code ↔ Paper reader above.
1874309276/si_ln_brain_health
10770d821f785f45e4ee64d203a34ab30a8dea4a, 21 January 2026Availability: 1 check, the latest on 30 September 2026: the link answers
- 30 September 2026: the link answers
1 file
- README.md, Text, 1 line
Zenodo 18322969
Availability: 1 check, the latest on 30 September 2026: the link answers (HTTP 200)
- 30 September 2026: the link answers (HTTP 200)
1 file
- README.md, Text, 1 line
Code availability statement
The paper has a code availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:
- it points to the authors' code: 1874309276/
si_ln_brain_health
Read it in the paper: doi.org/10.1038/s41467-026-72529-y.
Tracing map
Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.
What the map holds:
- 2 repositories of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
- 0 scripts, each with its path and the digest of its content;
- no match between paragraphs and code yet;
- neither the text of the paper nor the code itself.
Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.
Data
Datasets cited
- ams.ukbiobank.ac.uk/
ams , at UK Biobank; found in “Data availability” - ukbiobank.ac.uk/
learn-more-about-uk-biob , at UK Biobank; found in the text, “Participants”ank/ about-us
Data availability statement
The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:
- it points to a dataset: ams.ukbiobank.ac.uk/
ams
Read it in the paper: doi.org/10.1038/s41467-026-72529-y.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 1, 30 September 2026: the first record
Recorded: type, language, journal, volume, issue, pages, dates, 13 authors, 2 keywords, 17 MeSH terms, 1 funder, 116 references.
Cite
This paper
Zhao, Y.-L., Zhang, D.-D., Gao, P.-Y., Fu, Y., Ge, Y.-J., Chi, H.-C., Guo, Z.-X., Yu, H.-H., Feng, J.-F., Tan, L., Cheng, W., Zhang, Y.-R., & Yu, J.-T. (2026). Associations of social isolation and loneliness with neurological disorders, psychiatric disorders, brain structures and behavioural phenotypes among UK Biobank participants. Nature communications, 17(1), 5818. https://
BibTeX
@article{zhao2026associa
author = {Zhao, Yong-Li and Zhang, Dan-Dan and Gao, Pei-Yang and Fu, Yan and Ge, Yi-Jun and Chi, Hao-Chen and Guo, Ze-Xin and Yu, Hai-Hong and Feng, Jian-Feng and Tan, Lan and Cheng, Wei and Zhang, Ya-Ru and Yu, Jin-Tai},
title = {{Associations of social isolation and loneliness with neurological disorders, psychiatric disorders, brain structures and behavioural phenotypes among UK Biobank participants}},
journal = {Nature communications},
year = {2026},
month = apr,
volume = {17},
number = {1},
pages = {5818},
publisher = {Nature Publishing Group},
issn = {2041-1723},
doi = {10.1038/
url = {https://
pmid = {42049746},
pmcid = {PMC13328319}
}
RIS
TY - JOUR
AU - Zhao, Yong-Li
AU - Zhang, Dan-Dan
AU - Gao, Pei-Yang
AU - Fu, Yan
AU - Ge, Yi-Jun
AU - Chi, Hao-Chen
AU - Guo, Ze-Xin
AU - Yu, Hai-Hong
AU - Feng, Jian-Feng
AU - Tan, Lan
AU - Cheng, Wei
AU - Zhang, Ya-Ru
AU - Yu, Jin-Tai
TI - Associations of social isolation and loneliness with neurological disorders, psychiatric disorders, brain structures and behavioural phenotypes among UK Biobank participants
T2 - Nature communications
J2 - Nat Commun
PY - 2026
DA - 2026/
VL - 17
IS - 1
SP - 5818
SN - 2041-1723
PB - Nature Publishing Group
DO - 10.1038/
UR - https://
LA - en
ER -
CSL-JSON
{
"id": "10.1038/
"type": "article-journal",
"title": "Associations of social isolation and loneliness with neurological disorders, psychiatric disorders, brain structures and behavioural phenotypes among UK Biobank participants",
"container-title": "Nature communications",
"author": [
{
"family": "Zhao",
"given": "Yong-Li"
},
{
"family": "Zhang",
"given": "Dan-Dan"
},
{
"family": "Gao",
"given": "Pei-Yang"
},
{
"family": "Fu",
"given": "Yan"
},
{
"family": "Ge",
"given": "Yi-Jun"
},
{
"family": "Chi",
"given": "Hao-Chen"
},
{
"family": "Guo",
"given": "Ze-Xin"
},
{
"family": "Yu",
"given": "Hai-Hong"
},
{
"family": "Feng",
"given": "Jian-Feng"
},
{
"family": "Tan",
"given": "Lan"
},
{
"family": "Cheng",
"given": "Wei"
},
{
"family": "Zhang",
"given": "Ya-Ru"
},
{
"family": "Yu",
"given": "Jin-Tai"
}
],
"container-title-short":
"volume": "17",
"issue": "1",
"page": "5818",
"DOI": "10.1038/
"PMID": "42049746",
"PMCID": "PMC13328319",
"ISSN": "2041-1723",
"publisher": "Nature Publishing Group",
"URL": "https://
"language": "en",
"issued": {
"date-parts": [
[
2026,
4,
28
]
]
}
}
The tracing map gets a citation of its own once an author has validated it and it has a DOI.
Similar papers
The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.
- [1] doi:10.3389/fpsyt.2026.1696515 [code]
- Loneliness in adolescents and youth with bipolar disorder: a scoping review.Journal: Frontiers in psychiatryIn common: 7 references
- [2] doi:10.1371/journal.pcbi.1014422 [code]
- Deciphering cell type-specific causal genetic effects on brain imaging-derived phenotypes and disorders with single-cell Mendelian randomization.Journal: PLoS computational biologyIn common: genetics / omics, 7 references
- [3] doi:10.1044/2026_jslhr-25-00615
- A Moderated Mediation Model Linking Speech-in-Noise Exposure, Speech Perception in Noise Ability, Loneliness, and Depression.Journal: Journal of speech, language, and hearing research : JSLHRIn common: depression, cognitive, 4 references
- [4] doi:10.1038/s41598-026-51734-1 [code]
- Genome-wide association study of positive and negative affect reveals shared genetic architecture and a potential causal relationship with cognition.Journal: Scientific reportsIn common: depression, cognitive, genetics / omics, 4 references
- [5] doi:10.1007/s00406-026-02302-1 [code]
- Exploring the genetic correlation between inflammatory bowel disease and psychiatric disorders: insights from genome-wide association studies.Journal: European archives of psychiatry and clinical neuroscienceIn common: genetics / omics, 5 references
- [6] doi:10.1111/jcpp.70178 [code]
- What makes a lonely child: environmental, health, and multimodal neuroimaging correlates of prospective loneliness in the ABCD study.Journal: Journal of child psychology and psychiatry, and allied disciplinesIn common: 4 references
- [7] doi:10.1016/j.bpsgos.2026.100719 [code]
- Spatial Mapping of Genetic Liability to Psychiatric Disorders in the Adult Human Hippocampus.Journal: Biological psychiatry global open scienceIn common: schizophrenia / psychosis, depression, genetics / omics, 3 references
- [8] doi:10.1038/s41467-026-73153-6 [code]
- Latent neural architecture organising shared aesthetic evaluations of visual artworks.Journal: Nature communicationsIn common: cognitive, author Jianfeng Feng
- [9] doi:10.3389/fnagi.2026.1792887
- Systematic proteomics reveals plasma NEFL as a robust predictor and pathological associate in &
lt;i& gt;C9ORF72& lt;/ i& gt;-related neurodegeneration. Journal: Frontiers in aging neuroscienceIn common: ukbiobank.ac.uk/learn-more-about-uk-biobank/about-us, genetics / omics - [10] doi:10.1038/s41467-026-70694-8 [code]
- Shared genetic and neuroimmune architecture links type 1 diabetes with neurocognitive traits.Journal: Nature communicationsIn common: genetics / omics, 4 references
Contribute
The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.
Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.
Claim this paper
Correct its record
Say what each link of this record is, remove the ones that are not the paper's, add the ones that are missing. The correction becomes a new version of the record, in its Versions section.
Validate its tracing map
You validate the map as this page shows it: 2 repositories of the authors' code, each at its verified commit and with its license, 0 scripts, and 0 matches between paragraphs and code (see the Code and Map sections). It then receives a DOI on Zenodo, with you (your ORCID iD) and OSCR as its creators; the code itself is not deposited.
The map's fingerprint: sha256:2d59b02acdedbd50…
Add the badge to its README
The badge links the code to this page. Copy one of these into the README of the paper's code: only you decide where it goes, and nothing is changed for you.
Markdown
[, paste the snippet at the top, then “Commit changes…” and, to review it first, “Create a new branch and start a pull request”. You open the pull request; OSCR asks for no permission.
Request its removal
To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).
Discussion, reproductions, activity
Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.
Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.
Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.