OSCR

Thalamo-cortical synchrony shapes seizure expression in human temporal lobe epilepsy.

Overview

Authors: Thandar Aung1, Jian Li2,3, Tipakorn Tumnark1, Chandana Belly1, John Thomas4,5, Kassem Jaber5,6, Prachi Parikh5, Muhammad Zafar7,8, Derek Southwell7, Patrick Chauvel9, Birgit Frauscher5,6,10, Jorge Gonzalez-Martinez11
ORCID iDs: Thandar Aung, Jian Li, Tipakorn Tumnark, John Thomas, Kassem Jaber, Derek Southwell, Birgit Frauscher, Jorge Gonzalez-Martinez
  1. Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, PA USA
  2. Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Massachusetts, Charlestown, MA USA
  3. Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Massachusetts, Boston, MA USA
  4. Department of Electrical and Computer Engineering Technology, Rochester Institute of Technology, Rochester, NY USA
  5. Department of Neurology, Duke University School of Medicine, Durham, NC USA
  6. Department of Biomedical Engineering, Duke University School of Medicine, Durham, NC USA
  7. Department of Neurosurgery, Duke University School of Medicine, Durham, NC USA
  8. Department of Pediatrics, Duke University School of Medicine, Durham, NC USA
  9. Department of Epilepsy, Cleveland Clinic Foundation, Cleveland, OH USA
  10. Analytical Neurophysiology Lab, McGill University, Montréal, Québec, Canada
  11. Department of Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA USA
Institutions: University of Pittsburgh (United States); University of Pittsburgh Medical Center (United States); Harvard University (United States); Massachusetts General Hospital (United States); Athinoula A. Martinos Center for Biomedical Imaging (United States); Rochester Institute of Technology (United States); Duke University (United States); Duke Medical Center (United States); Montreal Neurological Institute and Hospital (Canada); Cleveland Clinic (United States); McGill University (Canada)
Journal: Nature communications, volume 17, issue 1, article 7605
Dates: received 20 August 2025; accepted 28 April 2026; published online 25 May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41467-026-73053-9 · PMID 42185273 · PMCID PMC13424572 · OpenAlex W4413764637
Open access: gold, a free copy (OpenAlex)
Preprint: doi:10.21203/rs.3.rs-7419263/v1
Status: dead link
Categories: EEG (modality), human (organism), epilepsy (population), clinical / translational (subfield)
Methods: Statistics, Smoothing, state filtering, decompositions, Preprocessing, Spectral & time-frequency, Connectivity
Keywords: Translational research, Diagnostic markers
MeSH: Cerebral Cortex*, Drug Resistant Epilepsy*, Epilepsy, Temporal Lobe*, Seizures*, Thalamus*, Adolescent, Adult, Electroencephalography, Female, Humans, Male, Middle Aged, Young Adult (* major topic)
Topic: Neuroscience and Neuropharmacology Research (Cellular and Molecular Neuroscience, Neuroscience), according to OpenAlex
Funding: University of Pittsburgh; Government of Canada (175056, PJT-175056); Medical Center, University of Pittsburgh; Canadian Institutes of Health Research (175056_1)
Citations: cited by 2 papers (Europe PMC); 57 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

No file of the authors' code could be read here: it is described below, and read at its source.

silencer1127.github.io/software

License: none: the authors keep all their rights
State: the link is dead, verified on 28 September 2026
Evidence: found in the paper
Software Heritage: not checked
Found in: “Data availability”
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 28 September 2026: the link is dead (HTTP 404)
  • 28 September 2026: the link is dead (HTTP 404)
At the source: silencer1127.github.io/software/EZ_Fingerprint/ezf_main.Reference

The paper's code and data availability statement is in the Data section.

Tracing map

Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.

What the map holds:

  • 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
  • 0 scripts, each with its path and the digest of its content;
  • no match between paragraphs and code yet;
  • neither the text of the paper nor the code itself.

Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

No dataset and no data link were found in the paper.

Code and data availability statement

The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

Read it in the paper: doi.org/10.1038/s41467-026-73053-9.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 2, 28 September 2026

  • Funding: added University of Pittsburgh; Government of Canada: 175056, PJT-175056; Medical Center, University of Pittsburgh; Canadian Institutes of Health Research: 175056_1

Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 12 authors, 2 keywords, 13 MeSH terms, 52 references.

Cite

This paper

Aung, T., Li, J., Tumnark, T., Belly, C., Thomas, J., Jaber, K., Parikh, P., Zafar, M., Southwell, D., Chauvel, P., Frauscher, B., & Gonzalez-Martinez, J. (2026). Thalamo-cortical synchrony shapes seizure expression in human temporal lobe epilepsy. Nature communications, 17(1), 7605. https://doi.org/10.1038/s41467-026-73053-9

BibTeX

@article{aung2026thalamo,
author = {Aung, Thandar and Li, Jian and Tumnark, Tipakorn and Belly, Chandana and Thomas, John and Jaber, Kassem and Parikh, Prachi and Zafar, Muhammad and Southwell, Derek and Chauvel, Patrick and Frauscher, Birgit and Gonzalez-Martinez, Jorge},
title = {{Thalamo-cortical synchrony shapes seizure expression in human temporal lobe epilepsy}},
journal = {Nature communications},
year = {2026},
month = may,
volume = {17},
number = {1},
pages = {7605},
publisher = {Nature Publishing Group},
issn = {2041-1723},
doi = {10.1038/s41467-026-73053-9},
url = {https://doi.org/10.1038/s41467-026-73053-9},
pmid = {42185273},
pmcid = {PMC13424572}
}

RIS

TY - JOUR
AU - Aung, Thandar
AU - Li, Jian
AU - Tumnark, Tipakorn
AU - Belly, Chandana
AU - Thomas, John
AU - Jaber, Kassem
AU - Parikh, Prachi
AU - Zafar, Muhammad
AU - Southwell, Derek
AU - Chauvel, Patrick
AU - Frauscher, Birgit
AU - Gonzalez-Martinez, Jorge
TI - Thalamo-cortical synchrony shapes seizure expression in human temporal lobe epilepsy
T2 - Nature communications
J2 - Nat Commun
PY - 2026
DA - 2026/05/25
VL - 17
IS - 1
SP - 7605
SN - 2041-1723
PB - Nature Publishing Group
DO - 10.1038/s41467-026-73053-9
UR - https://doi.org/10.1038/s41467-026-73053-9
LA - en
ER -

CSL-JSON

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The tracing map gets a citation of its own once an author has validated it and it has a DOI.

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