OSCR

Optimization of connectome weights for a neural network model generating both forward and backward locomotion in C. elegans.

Overview

Authors: Taegon Chung1, Sangyeol Kim1
ORCID iDs: Taegon Chung
  1. Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology, Daegu, 42988 Korea
Institutions: Daegu Gyeongbuk Institute of Science and Technology (South Korea)
Journal: Scientific reports, volume 16, issue 1, article 21630
Dates: received 13 February 2026; accepted 19 May 2026; published online 21 May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41598-026-54384-5 · PMID 42168461 · PMCID PMC13354769 · OpenAlex W4412934689
Open access: gold, a free copy (OpenAlex)
Preprint: doi:10.1101/2025.07.21.665845
Status: data only
Categories: computational modeling (no new data) (modality), C. elegans (organism)
Methods: Machine learning
Keywords: C. elegans, Neural network simulation, Neural dynamics, Synapse-to-behavior, Machine-learning, Computational biology and bioinformatics, Neuroscience
MeSH: Caenorhabditis elegans*, Connectome*, Locomotion*, Models, Neurological*, Nerve Net*, Neural Networks, Computer*, Animals, Neurons, Synapses (* major topic)
Topic: Genetics, Aging, and Longevity in Model Organisms (Aging, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Funding: pCoE program of DGIST (23-CoE-BT-01)
Citations: not cited yet (Europe PMC); 63 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper links to its data, not to its authors' code: see the Data section.

Tracing map

A tracing map links a paper to the code its authors published: this paper has none, so it has no map.

Data

Datasets cited

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

Read it in the paper: doi.org/10.1038/s41598-026-54384-5.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 2 authors, 7 keywords, 9 MeSH terms, 1 funder, 54 references.

Cite

This paper

Chung, T., & Kim, S. (2026). Optimization of connectome weights for a neural network model generating both forward and backward locomotion in C. elegans. Scientific reports, 16(1), 21630. https://doi.org/10.1038/s41598-026-54384-5

BibTeX

@article{chung2026optimization,
author = {Chung, Taegon and Kim, Sangyeol},
title = {{Optimization of connectome weights for a neural network model generating both forward and backward locomotion in C. elegans}},
journal = {Scientific reports},
year = {2026},
month = may,
volume = {16},
number = {1},
pages = {21630},
publisher = {Nature Publishing Group},
issn = {2045-2322},
doi = {10.1038/s41598-026-54384-5},
url = {https://doi.org/10.1038/s41598-026-54384-5},
pmid = {42168461},
pmcid = {PMC13354769}
}

RIS

TY - JOUR
AU - Chung, Taegon
AU - Kim, Sangyeol
TI - Optimization of connectome weights for a neural network model generating both forward and backward locomotion in C. elegans
T2 - Scientific reports
J2 - Sci Rep
PY - 2026
DA - 2026/05/21
VL - 16
IS - 1
SP - 21630
SN - 2045-2322
PB - Nature Publishing Group
DO - 10.1038/s41598-026-54384-5
UR - https://doi.org/10.1038/s41598-026-54384-5
LA - en
ER -

CSL-JSON

{
"id": "10.1038/s41598-026-54384-5",
"type": "article-journal",
"title": "Optimization of connectome weights for a neural network model generating both forward and backward locomotion in C. elegans",
"container-title": "Scientific reports",
"author": [
{
"family": "Chung",
"given": "Taegon"
},
{
"family": "Kim",
"given": "Sangyeol"
}
],
"container-title-short": "Sci Rep",
"volume": "16",
"issue": "1",
"page": "21630",
"DOI": "10.1038/s41598-026-54384-5",
"PMID": "42168461",
"PMCID": "PMC13354769",
"ISSN": "2045-2322",
"publisher": "Nature Publishing Group",
"URL": "https://doi.org/10.1038/s41598-026-54384-5",
"language": "en",
"issued": {
"date-parts": [
[
2026,
5,
21
]
]
}
}

Similar papers

The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.

[1] doi:10.1371/journal.pcbi.1014152 [code]
Synchronization properties in C. elegans: Relating behavioral circuits to structural and functional neuronal connectivity.
Journal: PLoS computational biology
In common: C. elegans, 18 references
[2] doi:10.1038/s41593-026-02257-5 [code]
Neural sequences underlying directed turning in Caenorhabditis elegans.
Journal: Nature neuroscience
In common: C. elegans, 10 references
[3] doi:10.1186/s12915-026-02641-4
Signed motif analysis of the Caenorhabditis elegans neuronal network reveals positive feedforward and negative feedback loops.
Journal: BMC biology
In common: C. elegans, 8 references
[4] doi:10.1038/s41467-026-75352-7 [code]
Mechanosensory encoding of surface mechanics optimizes locomotion.
Journal: Nature communications
In common: C. elegans, 7 references
[5] doi:10.1038/s41467-026-72710-3 [code]
A modular multi-color fluorescence microscope for simultaneous tracking of cellular activity and behavior.
Journal: Nature communications
In common: C. elegans, 5 references
[6] doi:10.1126/sciadv.adv8387 [code]
<i>C. elegans</i> somatostatin/allatostatin C signaling regulates sleep, metabolism, survival, and memory via a sleep-active neuron.
Journal: Science advances
In common: C. elegans, 5 references
[7] doi:10.1038/s41467-026-76320-x [code]
Intrinsic and non-cell-autonomous roles for the neurodevelopmental syndrome-linked transcription factor UNC-3/EBF.
Journal: Nature communications
In common: C. elegans, 5 references
[8] doi:10.1098/rstb.2024.0461 [code]
Shallow recurrent decoders for neural and behavioural dynamics.
Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences
In common: C. elegans, 4 references
[9] doi:10.1016/j.celrep.2026.117288
Interlocked transcription factor feedback loops maintain and restore adult touch sensation.
Journal: Cell reports
In common: 4 references
[10] doi:10.7554/elife.102309 [code]
Dimorphic neural network architecture prioritizes sexual-related behaviors in male <i>Caenorhabditis elegans</i>.
Journal: eLife
In common: C. elegans, 3 references

Contribute

The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.

Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.

Request its removal

To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).

Discussion, reproductions, activity

Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.

Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.

Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.