OSCR

Integrated proteomic, transcriptomic, and epigenomic profiling identifies SRA1 as a novel therapeutic target for postpartum depression.

Overview

Authors: Ming Chen1, Qinling Wei2, Haowen Li3, Huangtao Ruan4, Linyan Fu1, Junxiao Ma2,5, Xiaowei Xia2, Yanting Liao6, Cailan Hou1, Haozhang Huang4
  1. Guangdong Mental Health Center, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University,Guangzhou, China
  2. Department of Psychiatry, The Third Affiliated Hospital of Sun Yat-sen University,Guangzhou, China
  3. Department of Obstetrics, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University,Guangzhou, China
  4. Department of Cardiology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University,Guangzhou, China
  5. Department of Psychiatry, Beijing Huilongguan Hospital,Beijing, China
  6. The Second School of Clinical Medicine, Southern Medical University,Guangzhou, China
Institutions: Southern Medical University (China); Third Affiliated Hospital of Sun Yat-sen University (China); Beijing HuiLongGuan Hospital (China)
Journal: Npj mental health research, volume 5, issue 1, article 44
Dates: received 15 December 2025; accepted 13 July 2026; published online 15 August 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s44184-026-00232-3 · PMID 42629404 · PMCID PMC13498596 · OpenAlex W7203535240
Open access: gold, a free copy (OpenAlex)
Status: code on request
Categories: genetics / omics (modality), depression (population), clinical / translational (subfield)
Methods: Statistics
Keywords: Biomarkers, Computational biology and bioinformatics, Diseases, Genetics, Medical research, Neuroscience
Topic: Neuroendocrine regulation and behavior (Social Psychology, Psychology), according to OpenAlex
Citations: not cited yet (Europe PMC); 75 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Code availability statement

The paper has a code availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the code is available on request

Read it in the paper: doi.org/10.1038/s44184-026-00232-3.

Tracing map

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Data

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Data availability statement

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  • no repository, dataset or request procedure was recognized in it

Read it in the paper: doi.org/10.1038/s44184-026-00232-3.

Versions

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Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 10 authors, 6 keywords, 75 references.

Cite

This paper

Chen, M., Wei, Q., Li, H., Ruan, H., Fu, L., Ma, J., Xia, X., Liao, Y., Hou, C., & Huang, H. (2026). Integrated proteomic, transcriptomic, and epigenomic profiling identifies SRA1 as a novel therapeutic target for postpartum depression. Npj mental health research, 5(1), 44. https://doi.org/10.1038/s44184-026-00232-3

BibTeX

@article{chen2026integrated,
author = {Chen, Ming and Wei, Qinling and Li, Haowen and Ruan, Huangtao and Fu, Linyan and Ma, Junxiao and Xia, Xiaowei and Liao, Yanting and Hou, Cailan and Huang, Haozhang},
title = {{Integrated proteomic, transcriptomic, and epigenomic profiling identifies SRA1 as a novel therapeutic target for postpartum depression}},
journal = {Npj mental health research},
year = {2026},
month = aug,
volume = {5},
number = {1},
pages = {44},
publisher = {Nature Publishing Group},
issn = {2731-4251},
doi = {10.1038/s44184-026-00232-3},
url = {https://doi.org/10.1038/s44184-026-00232-3},
pmid = {42629404},
pmcid = {PMC13498596}
}

RIS

TY - JOUR
AU - Chen, Ming
AU - Wei, Qinling
AU - Li, Haowen
AU - Ruan, Huangtao
AU - Fu, Linyan
AU - Ma, Junxiao
AU - Xia, Xiaowei
AU - Liao, Yanting
AU - Hou, Cailan
AU - Huang, Haozhang
TI - Integrated proteomic, transcriptomic, and epigenomic profiling identifies SRA1 as a novel therapeutic target for postpartum depression
T2 - Npj mental health research
J2 - Npj Ment Health Res
PY - 2026
DA - 2026/08/15
VL - 5
IS - 1
SP - 44
SN - 2731-4251
PB - Nature Publishing Group
DO - 10.1038/s44184-026-00232-3
UR - https://doi.org/10.1038/s44184-026-00232-3
LA - en
ER -

CSL-JSON

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"publisher": "Nature Publishing Group",
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"language": "en",
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