OSCR

Traveling-wave transcranial alternating current stimulation (twtACS) causally links neural timing to cognitive function.

Overview

Authors: Sangjun Lee1, Jimin Park1, Ivan Alekseichuk2, Taylor A. Berger1, Ana M. G. Manea3,4, Harry Tran1, Gabriela Delgado Salazar3,4, Seth D. König5,6, Alexander B. Herman6, David P. Darrow5,6, Jan Zimmermann1,3,4, Alexander Opitz1
ORCID iDs: Sangjun Lee, Jimin Park, Ivan Alekseichuk, Taylor A. Berger, Ana M. G. Manea, Harry Tran, Gabriela Delgado Salazar, Seth D. König, Alexander B. Herman, David P. Darrow, Alexander Opitz
  1. Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455
  2. Stephen M. Stahl Center for Psychiatric Neuroscience, Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL 60611
  3. Department of Neuroscience, University of Minnesota, Minneapolis, MN 55455
  4. Department of Radiology, Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN 55455
  5. Department of Neurosurgery, University of Minnesota, Minneapolis, MN 55455
  6. Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN 55455
Institutions: University of Minnesota (United States); Indiana University School of Medicine
Journal: Proceedings of the National Academy of Sciences of the United States of America, volume 123, issue 19, article e2527296123
Dates: received 25 September 2025; accepted 1 April 2026; published online 5 May 2026; in print 12 May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1073/pnas.2527296123 · PMID 42085148 · PMCID PMC13167727 · OpenAlex W7160238994
Open access: hybrid, a free copy (OpenAlex)
Status: data only
Categories: other (modality), intracranial EEG (iEEG / ECoG / SEEG) (modality), human (organism), non-human primate (organism), cognitive (subfield)
Keywords: cortical traveling waves, noninvasive brain stimulation, neural timing, cognition, intracranial recordings
MeSH: Brain*, Cognition*, Transcranial Direct Current Stimulation*, Adult, Animals, Cognitive Enhancement, Female, Humans, Macaca mulatta, Male, Neurons (* major topic)
Journal subjects: Biological Sciences, Neuroscience, Physical Sciences, Biophysics and Computational Biology
Topic: Transcranial Magnetic Stimulation Studies (Neurology, Neuroscience), according to OpenAlex
Funding: HHS | NIH | National Institute of Mental Health (NIMH) (RF1MH124909); University of Minnesota (MnDRIVE Initiative, Minnesota Partnership for Biotechnology and Medical Genomics (MNP) program); Brain and Behavior Research Foundation (Brain & Behavior Research Foundation) (a NARSAD Young Investigator Grant)
Citations: cited by 1 paper (Europe PMC); 67 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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The paper's code and data availability statement is in the Data section.

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Data

Datasets cited

Code and data availability statement

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Read it in the paper: doi.org/10.1073/pnas.2527296123.

Versions

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Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 12 authors, 5 keywords, 11 MeSH terms, 3 funders, 67 references.

Cite

This paper

Lee, S., Park, J., Alekseichuk, I., Berger, T. A., Manea, A. M. G., Tran, H., Delgado Salazar, G., König, S. D., Herman, A. B., Darrow, D. P., Zimmermann, J., & Opitz, A. (2026). Traveling-wave transcranial alternating current stimulation (twtACS) causally links neural timing to cognitive function. Proceedings of the National Academy of Sciences of the United States of America, 123(19), e2527296123. https://doi.org/10.1073/pnas.2527296123

BibTeX

@article{lee2026traveling,
author = {Lee, Sangjun and Park, Jimin and Alekseichuk, Ivan and Berger, Taylor A. and Manea, Ana M. G. and Tran, Harry and Delgado Salazar, Gabriela and König, Seth D. and Herman, Alexander B. and Darrow, David P. and Zimmermann, Jan and Opitz, Alexander},
title = {{Traveling-wave transcranial alternating current stimulation (twtACS) causally links neural timing to cognitive function}},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
year = {2026},
month = may,
volume = {123},
number = {19},
pages = {e2527296123},
publisher = {National Academy of Sciences},
issn = {0027-8424},
doi = {10.1073/pnas.2527296123},
url = {https://doi.org/10.1073/pnas.2527296123},
pmid = {42085148},
pmcid = {PMC13167727}
}

RIS

TY - JOUR
AU - Lee, Sangjun
AU - Park, Jimin
AU - Alekseichuk, Ivan
AU - Berger, Taylor A.
AU - Manea, Ana M. G.
AU - Tran, Harry
AU - Delgado Salazar, Gabriela
AU - König, Seth D.
AU - Herman, Alexander B.
AU - Darrow, David P.
AU - Zimmermann, Jan
AU - Opitz, Alexander
TI - Traveling-wave transcranial alternating current stimulation (twtACS) causally links neural timing to cognitive function
T2 - Proceedings of the National Academy of Sciences of the United States of America
J2 - Proc Natl Acad Sci U S A
PY - 2026
DA - 2026/05/05
VL - 123
IS - 19
SP - e2527296123
SN - 0027-8424
PB - National Academy of Sciences
DO - 10.1073/pnas.2527296123
UR - https://doi.org/10.1073/pnas.2527296123
LA - en
ER -

CSL-JSON

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