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Neurophysiological dynamics related to perception, action, and language in schizophrenia.

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  1. [1] § MATERIALS AND METHODS › Structural MRI acquisition for MEG coregistration ↔ presurfer_example.m, the whole file · a weak match · score 0.63 · MP2RAGE, FreeSurfer, recon, INV2, UNI, presurfer · Report a mismatch

Paper

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The authors' code

MATLAB · 31 lines · 1.4 KB · no license · 1 match

  1. %% MP2RAGE pre-processing Start-to-finish
  2. UNI=fullfile(pwd,'sub-01_acq-MP2RAGE_mod-UNI_defaced.nii');
  3. INV2=fullfile(pwd,'sub-01_acq-MP2RAGE_mod-INV2_defaced.nii');
  4. % ########################################################################
  5. % STEP - 0 : (optional) MPRAGEise UNI
  6. % ########################################################################
  7. UNI_out = presurf_MPRAGEise(INV2,UNI); % Outputs presurf_MPRAGEise directory
  9. % ########################################################################
  10. % STEP - 1 : Pre-process INV2 to get STRIPMASK
  11. % ########################################################################
  12. presurf_INV2(INV2); % Outputs presurf_INV2 directory
  14. % ########################################################################
  15. % STEP - 3 : Pre-process UNI to get BRAINMASK
  16. % ########################################################################
  17. % Change UNI path to that of the MPRAGEised UNI if Step-0 was done
  18. if exist('UNI_out','var')
  19. presurf_UNI(UNI_out); % Outputs presurf_UNI directory
  20. else
  21. presurf_UNI(UNI);
  22. end
  24. % ########################################################################
  25. % STEP - 4 : Prepare for Freesurfer
  26. % ########################################################################
  28. % Load the MPRAGEised UNI image and STRIPMASK in ITK-SNAP
  29. % Clean the mask in the regions-of-interest and save
  30. % Multiply the MPRAGEised UNI with the manually edited STRIPMASK
  31. % Supply to recon-all

presurfer_example.m at commit af1f47f, no license · at the source

Overview

Authors: Hsi T. Wei1,2, Dominic Boutet3, Rukun Dou2,4, Jessica Ahrens2,5, Nadia Zeramdini2, Alban Voppel1,2, Fernando Gonzales-Aste1, Fatme Abboud2, Sylvain Baillet3,6,7, Lena Palaniyappan1,2
ORCID iDs: Hsi T. Wei, Rukun Dou, Jessica Ahrens, Fernando Gonzales-Aste, Sylvain Baillet, Lena Palaniyappan
  1. Department of Psychiatry, McGill University, Montreal, QC, Canada
  2. Douglas Research Centre, McGill University, Montreal, QC, Canada
  3. Montreal Neurological Institute, McGill University, Montreal, QC, Canada
  4. Faculty of Medicine, McGill University, Montreal, QC, Canada
  5. Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada
  6. Centre de recherche du Centre hospitalier de l’Université de Montréal
  7. Department of Neuroscience, University of Montreal, Montreal, QC, Canada
Institutions: Douglas Mental Health University Institute (Canada); McGill University (Canada); Centre Hospitalier de l’Université de Montréal (Canada); Université de Montréal (Canada)
Journal: Science advances, volume 12, issue 43, article eaeh5819
Dates: received 2 April 2026; accepted 15 September 2026; published online 21 October 2026; in print October 2026
Type: Research article · Language: English
License: CC BY
Identifiers: DOI 10.1126/sciadv.aeh5819 · PMID 42905830 · PMCID PMC13685960 · OpenAlex W7223097686
Open access: gold, a free copy (OpenAlex)
Status: code verified (how the code is found and verified)
Categories: MEG (modality), human (organism), schizophrenia / psychosis (population), cognitive (subfield)
Methods: Spectral & time-frequency, Connectivity, Statistics, Smoothing, state filtering, decompositions, Preprocessing, fMRI & imaging
MeSH: Language*, Perception*, Schizophrenia*, Adult, Female, Humans, Magnetoencephalography, Male (* major topic)
Journal subjects: Neuroscience, Psychological Science
Topic: Schizophrenia research and treatment (Psychiatry and Mental health, Medicine), according to OpenAlex
Funding: Wellcome Trust (314138/Z/24/Z); J.W. McConnell Family Foundation (Magnetoencephalography in Psychosis); Canada Foundation for Innovation (#43849); Mitacs (IT44173); Fonds de recherche du Québec (FRQ) (QBIN 35450); Fonds de Recherche du Québec - Santé (FRQS: 366934); Monique H. Bourgeois Chair in Developmental Disorders; Graham Boeckh Foundation
Citations: not cited yet (Europe PMC); 105 references in the paper

Abstract

Schizophrenia disrupts both how people perceive the world and how they express and act on their thoughts, yet these symptoms are usually studied separately. Using magnetoencephalography during multisensory and motor tasks, we tested whether reduced event-related beta-band (15 to 30 hertz) modulation, a signal implicated in predictive control, provides a candidate neural marker across these domains. Compared to healthy individuals, patients showed diminished beta changes during sensory processing and movement completion, suggesting reduced flexibility in updating internal models. This neural pattern covaried with audiovisual simultaneity-judgment behavior, disorganized natural speech, and greater clinical severity. These findings suggest that distributed beta modulation may serve as a candidate cross-domain marker associated with perceptual, motor, and language disturbances in schizophrenia, motivating future studies that directly test predictive updating mechanisms.

Reproduced under the paper's license (CC BY), from the paper cited above.

Repositories

Its files are read in the Code ↔ Paper reader above, with 1 match between paragraphs and lines of code.

srikash/presurfer

License: none: the authors keep all their rights
State: the link answers, verified on 25 October 2026
Evidence: files inventoried
Commit: af1f47fb61509d7e8fae0b3d55c63ec4f2b65b47, 10 October 2026
Languages: MATLAB (5)
Size: 7 files, 5 scripts
Software Heritage: archived
Found in: the text, “Structural MRI acquisition for MEG coregistratio”
Holds: README, CITATION.cff
Not found: license file, environment file, tests, continuous integration, documentation
Tools: SPM (4 files)
Availability: 1 check, the latest on 25 October 2026: the link answers
  • 25 October 2026: the link answers
6 files
At the source: github.com/srikash/presurfer

Zenodo 21401588

License: CC-BY-4.0
State: the link answers, verified on 25 October 2026
Evidence: files inventoried
Size: 1 file
Software Heritage: not checked
Found in: “Data, code, and materials availability:”
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 25 October 2026: the link answers (HTTP 200)
  • 25 October 2026: the link answers (HTTP 200)
At the source: doi.org/10.5281/zenodo.21401588

The paper's code and data availability statement is in the Data section.

Tracing map

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  • 5 scripts, each with its path and the digest of its content;
  • 1 match between paragraphs of the paper and lines of the code (method lexical-v1);
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Data

No dataset and no data link were found in the paper.

Data, code, and materials availability

All deidentified data and code needed to evaluate and reproduce the results in the paper are present in the paper and/or the Supplementary Materials and are archived in Zenodo at https://doi.org/10.5281/zenodo.21401588. This study did not generate new materials.

Reproduced under the paper's license (CC BY), from the paper cited above.

Versions

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Version 1, 25 October 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 10 authors, 8 MeSH terms, 8 funders, 104 references.

Cite

This paper

Wei, H. T., Boutet, D., Dou, R., Ahrens, J., Zeramdini, N., Voppel, A., Gonzales-Aste, F., Abboud, F., Baillet, S., & Palaniyappan, L. (2026). Neurophysiological dynamics related to perception, action, and language in schizophrenia. Science advances, 12(43), eaeh5819. https://doi.org/10.1126/sciadv.aeh5819

BibTeX

@article{wei2026neurophysiological,
author = {Wei, Hsi T. and Boutet, Dominic and Dou, Rukun and Ahrens, Jessica and Zeramdini, Nadia and Voppel, Alban and Gonzales-Aste, Fernando and Abboud, Fatme and Baillet, Sylvain and Palaniyappan, Lena},
title = {{Neurophysiological dynamics related to perception, action, and language in schizophrenia}},
journal = {Science advances},
year = {2026},
month = oct,
volume = {12},
number = {43},
pages = {eaeh5819},
publisher = {American Association for the Advancement of Science},
issn = {2375-2548},
doi = {10.1126/sciadv.aeh5819},
url = {https://doi.org/10.1126/sciadv.aeh5819},
pmid = {42905830},
pmcid = {PMC13685960}
}

RIS

TY - JOUR
AU - Wei, Hsi T.
AU - Boutet, Dominic
AU - Dou, Rukun
AU - Ahrens, Jessica
AU - Zeramdini, Nadia
AU - Voppel, Alban
AU - Gonzales-Aste, Fernando
AU - Abboud, Fatme
AU - Baillet, Sylvain
AU - Palaniyappan, Lena
TI - Neurophysiological dynamics related to perception, action, and language in schizophrenia
T2 - Science advances
J2 - Sci Adv
PY - 2026
DA - 2026/10/21
VL - 12
IS - 43
SP - eaeh5819
SN - 2375-2548
PB - American Association for the Advancement of Science
DO - 10.1126/sciadv.aeh5819
UR - https://doi.org/10.1126/sciadv.aeh5819
LA - en
ER -

CSL-JSON

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