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Aberrant Functional Lateralization and Interhemispheric Synergy in High Myopia: Insights From Neurotransmitter Distribution Signatures and Machine Learning Classification.

Overview

Authors: Lin Zhou1, Yuanyuan Wang2, Shumin Xiong1, Yu Ji1, Zhuo-er Dong1, Xianjun Zeng2, Xiao-rong Wu1
  1. Department of Ophthalmology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, People's Republic of China
  2. Department of Radiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, People's Republic of China
Journal: Investigative ophthalmology & visual science, volume 67, issue 8, article 37
Dates: received 26 November 2025; accepted 22 April 2026; published online 15 July 2026; in print July 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1167/iovs.67.8.37 · PMID 42454956 · PMCID PMC13387254 · OpenAlex W7168419785
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: fMRI (modality), human (organism)
Methods: Spectral & time-frequency, Statistics, Machine learning, Connectivity, fMRI & imaging
Keywords: high myopia (HM), resting-state functional magnetic resonance imaging (rs-fMRI), amplitude of low-frequency fluctuations, functional connectivity between homologous voxels (CFH), neurotransmitter dynamics, machine learning classification
MeSH: Functional Laterality*, Machine Learning*, Myopia*, Neurotransmitter Agents*, Adult, Brain Mapping, Female, Humans, Magnetic Resonance Imaging, Male, Young Adult (* major topic)
Journal subjects: Multidisciplinary Ophthalmic Imaging
Topic: Hemispheric Asymmetry in Neuroscience (Cognitive Neuroscience, Neuroscience), according to OpenAlex
Citations: not cited yet (Europe PMC); 110 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Versions

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Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 7 authors, 6 keywords, 11 MeSH terms, 109 references.

Cite

This paper

Zhou, L., Wang, Y., Xiong, S., Ji, Y., Dong, Z.-e., Zeng, X., & Wu, X.-r. (2026). Aberrant Functional Lateralization and Interhemispheric Synergy in High Myopia: Insights From Neurotransmitter Distribution Signatures and Machine Learning Classification. Investigative ophthalmology & visual science, 67(8), 37. https://doi.org/10.1167/iovs.67.8.37

BibTeX

@article{zhou2026aberrant,
author = {Zhou, Lin and Wang, Yuanyuan and Xiong, Shumin and Ji, Yu and Dong, Zhuo-er and Zeng, Xianjun and Wu, Xiao-rong},
title = {{Aberrant Functional Lateralization and Interhemispheric Synergy in High Myopia: Insights From Neurotransmitter Distribution Signatures and Machine Learning Classification}},
journal = {Investigative ophthalmology \& visual science},
year = {2026},
month = jul,
volume = {67},
number = {8},
pages = {37},
publisher = {Association for Research in Vision and Ophthalmology},
issn = {0146-0404},
doi = {10.1167/iovs.67.8.37},
url = {https://doi.org/10.1167/iovs.67.8.37},
pmid = {42454956},
pmcid = {PMC13387254}
}

RIS

TY - JOUR
AU - Zhou, Lin
AU - Wang, Yuanyuan
AU - Xiong, Shumin
AU - Ji, Yu
AU - Dong, Zhuo-er
AU - Zeng, Xianjun
AU - Wu, Xiao-rong
TI - Aberrant Functional Lateralization and Interhemispheric Synergy in High Myopia: Insights From Neurotransmitter Distribution Signatures and Machine Learning Classification
T2 - Investigative ophthalmology & visual science
J2 - Invest Ophthalmol Vis Sci
PY - 2026
DA - 2026/07/01
VL - 67
IS - 8
SP - 37
SN - 0146-0404
PB - Association for Research in Vision and Ophthalmology
DO - 10.1167/iovs.67.8.37
UR - https://doi.org/10.1167/iovs.67.8.37
LA - en
ER -

CSL-JSON

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"container-title": "Investigative ophthalmology & visual science",
"author": [
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"publisher": "Association for Research in Vision and Ophthalmology",
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"language": "en",
"issued": {
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