OSCR

Plasma proteome signatures are predictive of mortality in sickle cell disease.

Overview

Authors: Arnaud Chignon1,2, Yosr Zaouali3, Frédéric Galactéros3, Pablo Bartolucci3, Guillaume Lettre1,2
  1. Faculté de Médecine, Université de Montréal, Montréal, QC, Canada
  2. Montreal Heart Institute, Montréal, QC, Canada
  3. Red Cell Genetic Disease Unit, Hôpital Henri-Mondor, Assistance Publique–Hôpitaux de Paris, Université Paris-Est, Mondor Institute for Biomedical Research U955 Équipe no. 2, Créteil, France
Journal: Blood advances, volume 10, issue 10, pages 3420-3430
Dates: received 4 December 2025; accepted 22 February 2026; published online 23 March 2026; in print May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1182/bloodadvances.2025019294 · PMID 41855503 · PMCID PMC13195607 · OpenAlex W7138994481
Open access: gold, a free copy (OpenAlex)
Status: code verified
Categories: genetics / omics (modality), human (organism)
Methods: Statistics, Smoothing, state filtering, decompositions, Machine learning, Connectivity
MeSH: Anemia, Sickle Cell*, Blood Proteins*, Proteome*, Adult, Biomarkers, Female, Humans, Male, Middle Aged, Prognosis (* major topic)
Topic: Hemoglobinopathies and Related Disorders (Genetics, Medicine), according to OpenAlex
Citations: not cited yet (Europe PMC); 50 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

No file of the authors' code could be read here: it is described below, and read at its source.

mhi-humangenetics.org/en/resources

License: none: the authors keep all their rights
State: the link answers, verified on 28 September 2026
Evidence: the link answers
Software Heritage: not checked
Found in: the text, “Footnotes”
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 28 September 2026: the link answers (HTTP 200)
  • 28 September 2026: the link answers (HTTP 200)

Tracing map

Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.

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  • 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
  • 0 scripts, each with its path and the digest of its content;
  • no match between paragraphs and code yet;
  • neither the text of the paper nor the code itself.

Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

No dataset and no data link were found in the paper.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 2, 28 September 2026

  • Funding: added Canadian Institutes of Health Research

Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 5 authors, 10 MeSH terms, 49 references.

Cite

This paper

Chignon, A., Zaouali, Y., Galactéros, F., Bartolucci, P., & Lettre, G. (2026). Plasma proteome signatures are predictive of mortality in sickle cell disease. Blood advances, 10(10), 3420-3430. https://doi.org/10.1182/bloodadvances.2025019294

BibTeX

@article{chignon2026plasma,
author = {Chignon, Arnaud and Zaouali, Yosr and Galactéros, Frédéric and Bartolucci, Pablo and Lettre, Guillaume},
title = {{Plasma proteome signatures are predictive of mortality in sickle cell disease}},
journal = {Blood advances},
year = {2026},
month = may,
volume = {10},
number = {10},
pages = {3420--3430},
publisher = {The American Society of Hematology},
issn = {2473-9529},
doi = {10.1182/bloodadvances.2025019294},
url = {https://doi.org/10.1182/bloodadvances.2025019294},
pmid = {41855503},
pmcid = {PMC13195607}
}

RIS

TY - JOUR
AU - Chignon, Arnaud
AU - Zaouali, Yosr
AU - Galactéros, Frédéric
AU - Bartolucci, Pablo
AU - Lettre, Guillaume
TI - Plasma proteome signatures are predictive of mortality in sickle cell disease
T2 - Blood advances
J2 - Blood Adv
PY - 2026
DA - 2026/05/01
VL - 10
IS - 10
SP - 3420
EP - 3430
SN - 2473-9529
PB - The American Society of Hematology
DO - 10.1182/bloodadvances.2025019294
UR - https://doi.org/10.1182/bloodadvances.2025019294
LA - en
ER -

CSL-JSON

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The tracing map gets a citation of its own once an author has validated it and it has a DOI.

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