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Optimization of stimulus color for peripheral SSVEP-based brain-computer interfaces.

Overview

Authors: Haochen Liu1,2, Zhaohui Li1, Wenwen Li3, Ruoqi Yang4, Xiaogang Chen1
  1. Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
  2. School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, China
  3. CASIC-CQC Software Testing and Assessment Technology (Beijing) Co., Ltd., Beijing, China
  4. School of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, China
Journal: Frontiers in human neuroscience, volume 20, article 1832475
Dates: received 17 March 2026; accepted 12 June 2026; published online 30 June 2026
Type: Research article · Language: English
License: CC BY
Identifiers: DOI 10.3389/fnhum.2026.1832475 · PMID 42454243 · PMCID PMC13365271 · OpenAlex W7166647151
Open access: gold, a free copy (OpenAlex)
Status: code on request
Categories: EEG (modality), human (organism)
Methods: Spectral & time-frequency, Statistics, Smoothing, state filtering, decompositions, Physiology & signal measures
Keywords: brain-computer interfaces, color, electroencephalogram, peripheral vision field, steady-state visual evoked potentials
Topic: EEG and Brain-Computer Interfaces (Cognitive Neuroscience, Neuroscience), according to OpenAlex
Funding: Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences (2024-JKCS-26); CAMS Innovation Fund for Medical Sciences (2025-I2M-TS-10); Tianjin Municipal Science and Technology Project (24JCZDJC00430, 24JCJQJC00040); National Key Research and Development Program of China (2023YFF1205300); National Natural Science Foundation of China (62471495)
Citations: not cited yet (Europe PMC); 51 references in the paper

Abstract

Background: Most existing steady-state visual evoked potential (SSVEP)-based brain-computer interfaces (BCIs) struggle to balance user experience with system performance. Although recent studies have shown that peripheral vision stimulation can evoke SSVEPs with high user comfort, the impact of stimulus color on peripheral SSVEP performance remains underexplored. Therefore, this study attempted to investigate the effect of stimulus color on peripheral SSVEPs.

Methods: Four conventional stimulus colors (i.e., blue, green, red, and white) were evaluated using ultra-low frequency SSVEP stimuli, with the stimulation frequencies ranging from 2 Hz to 3.32 Hz. Based on the results, the optimized stimulus color was used to build a 12-target peripheral SSVEP-based BCI. Task-discriminant component analysis (TDCA) algorithm was adopted to detect SSVEPs. The feasibility of the proposed system was verified through offline experiments with 13 participants and online experiments with 11 participants.

Results: The offline experiments with 13 participants showed no significant differences in classification accuracy and information transfer rates (ITRs) among the four-color paradigms. However, green stimulation received the highest subjective comfort ratings. Consequently, green stimulation was selected for building the 12-target peripheral SSVEP-based BCI. The online results achieved a mean classification accuracy of 89.93 ± 6.10% and an ITR of 47.96 ± 6.98 bits/min.

Conclusion: The present findings support a comfort-driven color selection strategy for peripheral ultra-low-frequency SSVEP stimulation while maintaining comparable performance among the tested colors. These findings may provide practical guidance for more visually tolerable SSVEP-based BCI systems based on peripheral visual stimulation.

Reproduced under the paper's license (CC BY), from the paper cited above.

Code

The paper says that its authors' code is available on request: it was not published with the paper, so there is nothing to verify.

The paper's code and data availability statement is in the Data section.

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Data

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Data availability statement

The datasets presented in this article are not readily available because data and the programming code used as part of this research can be obtained from corresponding authors on reasonable request. Requests to access the datasets should be directed to .

Reproduced under the paper's license (CC BY), from the paper cited above.

Versions

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Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, pages, dates, 5 authors, 5 keywords, 5 funders, 49 references.

Cite

This paper

Liu, H., Li, Z., Li, W., Yang, R., & Chen, X. (2026). Optimization of stimulus color for peripheral SSVEP-based brain-computer interfaces. Frontiers in human neuroscience, 20, 1832475. https://doi.org/10.3389/fnhum.2026.1832475

BibTeX

@article{liu2026optimization,
author = {Liu, Haochen and Li, Zhaohui and Li, Wenwen and Yang, Ruoqi and Chen, Xiaogang},
title = {{Optimization of stimulus color for peripheral SSVEP-based brain-computer interfaces}},
journal = {Frontiers in human neuroscience},
year = {2026},
month = jun,
volume = {20},
pages = {1832475},
publisher = {Frontiers Media SA},
issn = {1662-5161},
doi = {10.3389/fnhum.2026.1832475},
url = {https://doi.org/10.3389/fnhum.2026.1832475},
pmid = {42454243},
pmcid = {PMC13365271}
}

RIS

TY - JOUR
AU - Liu, Haochen
AU - Li, Zhaohui
AU - Li, Wenwen
AU - Yang, Ruoqi
AU - Chen, Xiaogang
TI - Optimization of stimulus color for peripheral SSVEP-based brain-computer interfaces
T2 - Frontiers in human neuroscience
J2 - Front Hum Neurosci
PY - 2026
DA - 2026/06/30
VL - 20
SP - 1832475
SN - 1662-5161
PB - Frontiers Media SA
DO - 10.3389/fnhum.2026.1832475
UR - https://doi.org/10.3389/fnhum.2026.1832475
LA - en
ER -

CSL-JSON

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