Top-down feedback in deep neural networks leads to functional differences during audiovisual integration.
The 5 matches
- [1] § Methods › Model ↔ connectome_to_model/model/topdown_gru.py, lines 16–116 · score 0.73 · reset gate, update gate, hidden state, candidate, signal, channel
- [2] § Methods › Model ↔ connectome_to_model/model/topdown_gru.py, lines 16–116 · score 0.66 · ConvGRU, hidden state, Gated, cell, reset, signal
- [3] § Methods › Audiovisual task training › Training tasks ↔ scripts/multimodal_all_scenarios.py, lines 159–248 · score 0.63 · cross entropy loss, UAM, VS1, UUN, VS2, mismatched
- [4] § Methods › Audiovisual task training › Training tasks ↔ scripts/amb_audio_training.py, lines 155–226 · score 0.56 · cross entropy loss, UUN, mismatched, mix, shuffled, matching
- [5] § Methods › Stimuli generation and preprocessing › Ambiguous auditory stimuli ↔ connectome_to_model/utils/audio_dataset.py, lines 14–135 · score 0.54 · visual stimuli, 0–1, mel, FSDD, ambiguity, ambiguous
Paper
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The authors' code
Python · 253 lines · 11 KB · MIT · 2 matches
- import os
- import torch
- from torch import nn
- import torch.nn.functional as F
- def _resolve_device_dtype(device, dtype):
- """Fall back to CUDA when available, otherwise CPU, so the cells run on either."""
- if dtype is None:
- dtype = torch.cuda.FloatTensor if torch.cuda.is_available() else torch.FloatTensor
- if device is None:
- device = 'cuda' if torch.cuda.is_available() else 'cpu'
- return device, dtype
- class ConvGRUBasalTopDownCell(nn.Module):
- def __init__(self, input_size, input_dim, hidden_dim, kernel_size,
- basal_topdown_dim=0,
- apical_topdown_dim=0,
- bias=True,
- device=None,
- dtype=None):
- """
- Single ConvGRU block with topdown
- :param input_size: (int, int)
- Height and width of input tensor as (height, width).
- :param input_dim: int
- Number of channels of input tensor.
- :param hidden_dim: int
- Number of channels of hidden state.
- :param kernel_size: (int, int)
- Size of the convolutional kernel.
- :param apical_mechanism (str)
- 'multiplicative' or 'composite', how to combine top-down info within the block
- :param basal_topdown_dim (int)
- if there's no basal topdown input, use 0
- :param bias: bool
- Whether or not to add the bias.
- :param dtype: torch.cuda.FloatTensor or torch.FloatTensor
- Whether or not to use cuda.
- """
- super(ConvGRUBasalTopDownCell, self).__init__()
- self.height, self.width = input_size
- self.padding = kernel_size[0] // 2, kernel_size[1] // 2
- self.hidden_dim = hidden_dim
- self.bias = bias
- self.apical_topdown_dim = apical_topdown_dim
- self.basal_topdown_dim = basal_topdown_dim
- self.device, self.dtype = _resolve_device_dtype(device, dtype)
- # Basal compartment
- if basal_topdown_dim == 0:
- self.conv_gates = nn.Conv2d(in_channels=input_dim + hidden_dim,
- out_channels=2*self.hidden_dim, # for update_gate,reset_gate + 2*topdown
- kernel_size=kernel_size,
- padding= (kernel_size[0] // 2, kernel_size[1] // 2),
- bias=self.bias)
- else:
- self.conv_gates = nn.Conv2d(in_channels=input_dim + hidden_dim + basal_topdown_dim,
- out_channels=2*self.hidden_dim, # for update_gate,reset_gate + 2*topdown
- kernel_size=kernel_size,
- padding= (kernel_size[0] // 2, kernel_size[1] // 2),
- bias=self.bias)
- # Apical compartment
- self.conv_can = nn.Conv2d(in_channels=input_dim+hidden_dim+apical_topdown_dim,
- out_channels=self.hidden_dim, # for candidate neural memory
- kernel_size=kernel_size,
- padding=self.padding,
- bias=self.bias)
- def init_hidden(self, batch_size):
- return torch.zeros(batch_size, self.hidden_dim, self.height, self.width).type(self.dtype)
- def forward(self, input_tensor, h_cur, topdown):
- """
- :param self:
- :param input_tensor: (b, c, h, w)
- input is actually the target_model
- :param h_cur: (b, c_hidden, h, w)
- current hidden and cell states respectively
- :return: topdown: (b, c_topdown, h, w),
- topdown signal, either a direct clue or hidden of top layer
- """
- b, in_dim, h, w = input_tensor.shape
- mult_topdown_dim = in_dim + self.hidden_dim + 2*self.apical_topdown_dim
- if topdown is None:
- topdown = torch.zeros(b, mult_topdown_dim + self.basal_topdown_dim, h, w, device=input_tensor.device)
- # BASAL COMPARTMENT
- if self.basal_topdown_dim != 0:
- basal_topdown, topdown = torch.split(topdown, (self.basal_topdown_dim, topdown.shape[1]-self.basal_topdown_dim), dim=1)
- combined = torch.cat([input_tensor, h_cur, basal_topdown], dim=1)
- else:
- combined = torch.cat([input_tensor, h_cur], dim=1)
- combined_conv = self.conv_gates(combined)
- gamma, beta = torch.split(combined_conv, self.hidden_dim, dim=1)
- reset_gate = torch.sigmoid(gamma)
- update_gate = torch.sigmoid(beta)
- # APICAL COMPARTMENT
- if self.apical_topdown_dim != 0:
- add_topdown, mult_topdown = torch.split(topdown, (self.apical_topdown_dim, mult_topdown_dim - self.apical_topdown_dim), dim=1)
- combined = torch.cat([input_tensor, reset_gate*h_cur, add_topdown], dim=1) * (F.relu(mult_topdown) + 1)
- else:
- # multiplicative topdown
- combined = torch.cat([input_tensor, reset_gate*h_cur], dim=1) * (F.relu(topdown) + 1)
- cc_cnm = self.conv_can(combined)
- cnm = torch.tanh(cc_cnm)
- # MEMORY UPDATE
- h_next = (1 - update_gate) * h_cur + update_gate * cnm
- return h_next
- class ConvGRUTopDownCell(nn.Module):
- def __init__(self, input_size, input_dim, hidden_dim, kernel_size,
- topdown_type='multiplicative',
- bias=True,
- device=None,
- dtype=None):
- """
- Single ConvGRU block with topdown
- :param input_size: (int, int)
- Height and width of input tensor as (height, width).
- :param input_dim: int
- Number of channels of input tensor.
- :param hidden_dim: int
- Number of channels of hidden state.
- :param kernel_size: (int, int)
- Size of the convolutional kernel.
- :param topdown_type (str)
- 'multiplicative' or 'composite', how to combine top-down info within the block
- :param bias: bool
- Whether or not to add the bias.
- :param dtype: torch.cuda.FloatTensor or torch.FloatTensor
- Whether or not to use cuda.
- """
- super(ConvGRUTopDownCell, self).__init__()
- self.height, self.width = input_size
- self.padding = kernel_size[0] // 2, kernel_size[1] // 2
- self.hidden_dim = hidden_dim
- self.bias = bias
- self.device, self.dtype = _resolve_device_dtype(device, dtype)
- self.topdown_type = topdown_type
- if self.topdown_type == 'multiplicative':
- self.conv_gates = nn.Conv2d(in_channels=input_dim + hidden_dim,
- out_channels=2*self.hidden_dim, # for update_gate,reset_gate + 2*topdown
- kernel_size=kernel_size,
- padding= (kernel_size[0] // 2, kernel_size[1] // 2),
- bias=self.bias)
- elif self.topdown_type == 'composite':
- self.conv_gates = nn.Conv2d(in_channels=(input_dim + hidden_dim)*2,
- out_channels=2*self.hidden_dim, # for update_gate,reset_gate + 2*topdown
- kernel_size=kernel_size,
- padding= (kernel_size[0] // 2, kernel_size[1] // 2),
- bias=self.bias)
- else:
- raise ValueError(f"Unknown topdown_type '{topdown_type}'; expected 'multiplicative' or 'composite'")
- self.conv_can = nn.Conv2d(in_channels=input_dim+hidden_dim,
- out_channels=self.hidden_dim, # for candidate neural memory
- kernel_size=kernel_size,
- padding=self.padding,
- bias=self.bias)
- def init_hidden(self, batch_size):
- return torch.zeros(batch_size, self.hidden_dim, self.height, self.width).type(self.dtype)
- def forward(self, input_tensor, h_cur, topdown):
- """
- :param self:
- :param input_tensor: (b, c, h, w)
- input is actually the target_model
- :param h_cur: (b, c_hidden, h, w)
- current hidden and cell states respectively
- :return: topdown: (b, c_topdown, h, w),
- topdown signal, either a direct clue or hidden of top layer
- """
- combined = torch.cat([input_tensor, h_cur], dim=1)
- if topdown is None:
- topdown = torch.zeros_like(combined)
- if self.topdown_type == 'composite':
- combined = torch.cat([input_tensor, h_cur, topdown], dim=1)
- combined_conv = self.conv_gates(combined)
- gamma, beta = torch.split(combined_conv, self.hidden_dim, dim=1)
- reset_gate = torch.sigmoid(gamma)
- update_gate = torch.sigmoid(beta)
- combined = torch.cat([input_tensor, reset_gate*h_cur], dim=1) * (F.relu(topdown) + 1)
- cc_cnm = self.conv_can(combined)
- cnm = torch.tanh(cc_cnm)
- h_next = (1 - update_gate) * h_cur + update_gate * cnm
- return h_next
- class ILC_upsampler(nn.Module):
- def __init__(self, in_channel, out_channel, stride, device='cuda'):
- """
- Projection layer for upsampling. Prevents checkerboard effect of a single ConvT
- :param in_channel (int)
- :param out_channel (int)
- :param stride (int)
- """
- super(ILC_upsampler, self).__init__()
- self.c1 = nn.Sequential(nn.ConvTranspose2d(in_channels=in_channel,
- out_channels=out_channel,
- kernel_size=(1,1),
- stride=stride, device=device
- ),
- nn.ReLU(),
- nn.ZeroPad2d((0,1,0,1))
- )
- self.c2 = nn.Sequential(nn.ConvTranspose2d(in_channels=in_channel,
- out_channels=out_channel,
- kernel_size=(1,1),
- stride=stride, device=device
- ),
- nn.ReLU(),
- nn.ZeroPad2d((1,0,1,0))
- )
- self.c3 = nn.Sequential(nn.ConvTranspose2d(in_channels=in_channel,
- out_channels=out_channel,
- kernel_size=(1,1),
- stride=stride, device=device
- ),
- nn.ReLU(),
- nn.ZeroPad2d((1,0,0,1))
- )
- self.c4 = nn.Sequential(nn.ConvTranspose2d(in_channels=in_channel,
- out_channels=out_channel,
- kernel_size=(1,1),
- stride=stride, device=device
- ),
- nn.ReLU(),
- nn.ZeroPad2d((0,1,1,0))
- )
- def forward(self, z):
- c1_out=self.c1(z)
- c2_out=self.c2(z)
- c3_out=self.c3(z)
- c4_out=self.c4(z)
- upsampled_z=c1_out+c2_out+c3_out+c4_out
- return upsampled_z
topdown_gru.py at commit 8346d1c, under MIT · at the source
Overview
- McGill University, Montréal, Canada
- Mila Quebec AI Institute, Montréal, Canada
- Department of Neurosciences, Faculty of Medicine, Université de Montréal, Montréal, Canada
- Centre de Recherche Azrieli du CHU Sainte-Justine, Montréal, Canada
Abstract
Artificial neural networks (ANNs) are an important tool for studying neural computation, but many features of the brain are not captured by standard ANN architectures. One notable missing feature in most ANN models is top-down feedback, that is projections from higher-order layers to lower-order layers in the network. Top-down feedback is ubiquitous in the brain, and it has a unique modulatory impact on activity in neocortical pyramidal neurons. However, we still do not understand its computational role. Here, we develop a deep neural network model that captures the core functional properties of top-down feedback in the neocortex, allowing us to construct hierarchical recurrent ANN models that more closely reflect the architecture of the brain. We use this to explore the impact of different hierarchical recurrent architectures on an audiovisual integration task. We find that certain hierarchies, namely those that mimic the architecture of the human brain, impart ANN models with a light visual bias similar to that seen in humans. This bias does not impair performance on the audiovisual tasks. The results further suggest that different configurations of top-down feedback make otherwise identically connected models functionally distinct from each other, and from traditional feedforward and laterally recurrent models. Altogether, our findings demonstrate that modulatory top-down feedback is a computationally relevant feature of biological brains, and that incorporating it into ANNs affects their behavior and constrains the solutions it is likely to discover.
Reproduced under the paper's license (CC BY), from the paper cited above.
Repositories
Its files are read in the Code ↔ Paper reader above, with 5 matches between paragraphs and lines of code.
masht18/connectome-to-model
8346d1ce74d7bab27f5f297d443ab7195a5e35b8, 12 June 2026Availability: 1 check, the latest on 27 September 2026: the link answers
- 27 September 2026: the link answers
20 files
- connectome_to_model/
__init__.py , Python, 1 line - connectome_to_model/
model/ , Python, 370 linesarchitectures.py - connectome_to_model/
model/ , Python, 229 linesgraph.py - connectome_to_model/
model/ , Python, 48 linesreadouts.py - connectome_to_model/
model/ , Python, 253 lines, 2 matchestopdown_gru.py - connectome_to_model/
train.py , Python, 162 lines - connectome_to_model/
utils/ , Python, 243 lines, 1 matchaudio_dataset.py - connectome_to_model/
utils/ , Python, 201 linesdatagen.py - connectome_to_model/
utils/ , Python, 88 linesmech_eval.py - connectome_to_model/
utils/ , Python, 141 linesoscar_utils.py - mnist_tutorial.ipynb, Jupyter, 333 lines
- scripts/
amb_audio_training.py , Python, 247 lines, 1 match - scripts/
amb_digit_training.py , Python, 250 lines - scripts/
latent_analysis.py , Python, 147 lines - scripts/
multimodal_all_scenarios , Python, 248 lines, 1 match.py - scripts/
simple_audio.py , Python, 192 lines - scripts/
simple_training.py , Python, 163 lines - setup.py, Python, 91 lines
- tests/
test_smoke.py , Python, 110 lines - README.md, Text, 170 lines
ABL-Lab/ambiguous-dataset
12b891d7dbf7ac4ccc98acc3ad52497451d9d546, 25 April 2024Availability: 1 check, the latest on 27 September 2026: the link answers
- 27 September 2026: the link answers
25 files
- ambiguous/
__init__.py , Python, 1 line - ambiguous/
data_utils.py , Python, 39 lines - ambiguous/
dataset/ , Jupyter, 186 linesdata_figures.ipynb - ambiguous/
dataset/ , Python, 449 linesdataset.py - ambiguous/
dataset/ , Shell, 3 linesdownload_aemnist.sh - ambiguous/
dataset/ , Shell, 3 linesdownload_amnist.sh - ambiguous/
models/ , Python, 1 line__init__.py - ambiguous/
models/ , Python, 128 linesambiguous_generator.py - ambiguous/
models/ , Python, 358 linescvae.py - ambiguous/
models/ , Python, 35 linesreadout.py - ambiguous/
models/ , Python, 216 linesvae.py - ambiguous/
train/ , Python, 1 line__init__.py - ambiguous/
train/ , Python, 80 linestrain_EMNIST_cvae.py - ambiguous/
train/ , Python, 389 linestrain_MNIST_final_ccvae. py - ambiguous/
train/ , Jupyter, 309 linestrain_MNIST_final_conv.i pynb - ambiguous/
train/ , Shell, 18 linestrain_conv_cvae_emnist.s h - ambiguous/
train/ , Shell, 21 linestrain_script.sh - ambiguous/
train/ , Python, 43 linestrain_template.py - ambiguous/
train/ , Python, 272 linestrain_vae_readout.py - setup.py, Python, 16 lines
- tests/
GE_tests.py , Python, 73 lines - tests/
__init__.py , Python, 1 line - tests/
test_dataset.py , Python, 24 lines - LICENSE, License, 201 lines
- README.md, Text, 107 lines
The paper's code and data availability statement is in the Data section.
Tracing map
Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.
What the map holds:
- 2 repositories of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
- 42 scripts, each with its path and the digest of its content;
- 5 matches between paragraphs of the paper and lines of the code (method lexical-v1);
- neither the text of the paper nor the code itself.
Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.
Data
No dataset and no data link were found in the paper.
Code and data availability
The toolbox used to convert graphs to top-down recurrent neural networks (Connectome-to-Model) is publicly available at https://
The structural connectivity and histological data used to build the human brainlike model rely on the open-source Microstructure-Informed Connectomics (MICA-MICs) dataset (doi: 10.1101/
The unambiguous audiovisual task stimuli are derived from the publicly available MNIST handwritten digit database and the FSDD. Ambiguous visual stimuli were sourced from Islah et al., 2023: (https://
Reproduced under the paper's license (CC BY), from the paper cited above.
Data availability
Code for running all the experiments, constructing the models, and preprocessing FSDD datasets can be found at the open source codebase of the paper: https://
The following previously published datasets were used:
Islah N, Tugsbayar M, Gurbuz BT, Richards B, Muller EB, Etter G. 2025. Ambigious MNIST. GitHub. ABL-Lab/
Jackson Z, Souza C, Flaks J, Pan Y, Nicolas H. 2018. Free Spoken Digit Dataset (FSDD) GitHub. Jakobovski/
Royer J, Rodriguez-Cruces R, Tavakol S, Lariviere S, Herholz P, Li Q, Wael R, Paquola C, Benkarim O, Park B, Lowe AJ, Margulies D, Smallwood J, Bernasconi A, Bernasconi N, Frauscher B, Bernhardt BC. 2023. MICA-MICs. CONP. mica-mics
Reproduced under the paper's license (CC BY), from the paper cited above.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 1, 27 September 2026: the first record
Recorded: type, language, journal, volume, pages, dates, 4 authors, 1 keyword, 7 MeSH terms, 2 funders, 74 references.
Cite
This paper
Tugsbayar, M., Li, M., Muller, E. B., & Richards, B. (2026). Top-down feedback in deep neural networks leads to functional differences during audiovisual integration. eLife, 14, RP105953. https://
BibTeX
@article{tugsbayar2026to
author = {Tugsbayar, Mashbayar and Li, Mingze and Muller, Eilif B and Richards, Blake},
title = {{Top-down feedback in deep neural networks leads to functional differences during audiovisual integration}},
journal = {eLife},
year = {2026},
month = aug,
volume = {14},
pages = {RP105953},
publisher = {eLife Sciences Publications, Ltd},
issn = {2050-084X},
doi = {10.7554/
url = {https://
pmid = {42647275},
pmcid = {PMC13516690}
}
RIS
TY - JOUR
AU - Tugsbayar, Mashbayar
AU - Li, Mingze
AU - Muller, Eilif B
AU - Richards, Blake
TI - Top-down feedback in deep neural networks leads to functional differences during audiovisual integration
T2 - eLife
J2 - eLife
PY - 2026
DA - 2026/
VL - 14
SP - RP105953
SN - 2050-084X
PB - eLife Sciences Publications, Ltd
DO - 10.7554/
UR - https://
LA - en
ER -
CSL-JSON
{
"id": "10.7554/
"type": "article-journal",
"title": "Top-down feedback in deep neural networks leads to functional differences during audiovisual integration",
"container-title": "eLife",
"author": [
{
"family": "Tugsbayar",
"given": "Mashbayar"
},
{
"family": "Li",
"given": "Mingze"
},
{
"family": "Muller",
"given": "Eilif B"
},
{
"family": "Richards",
"given": "Blake"
}
],
"container-title-short":
"volume": "14",
"page": "RP105953",
"DOI": "10.7554/
"PMID": "42647275",
"PMCID": "PMC13516690",
"ISSN": "2050-084X",
"publisher": "eLife Sciences Publications, Ltd",
"URL": "https://
"language": "en",
"issued": {
"date-parts": [
[
2026,
8,
26
]
]
}
}
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