Toward neuroanatomical and cognitive foundations of macaque social tolerance grades.
Overview
- Laboratoire de Neurosciences Cognitives et Adaptatives, UMR 7364, Strasbourg, France
- Centre de Primatologie de l’Université de Strasbourg, Niederhausbergen, France
- ICube (UMR 7357), Université de Strasbourg-CNRS, Strasbourg, France
- Univ Lyon, Université Lyon, Inserm, Stem Cell and Brain Research Institute, U1208, Bron, France
- Wellcome Center for Neuroimaging, Dpt of Experimental Psychology, University of Oxford, Oxford, United Kingdom
Abstract
The macaque genus includes 25 species with diverse social systems, ranging from low to high social tolerance grades. Such interspecific behavioral variability provides a unique model to tackle the evolutionary foundation of primate social brain. Yet, the neuroanatomical correlates of these social tolerance grades remain unknown. To address this question, we expressed social tolerance grades within a novel cognitive framework and analyzed post-mortem structural scans from 12 macaque species. Our results show that amygdala volume is a subcortical predictor of macaques’ social tolerance, with high tolerance species exhibiting larger amygdala than low tolerance ones. We further investigated the developmental trajectory of amygdala across social grades and found that intolerant species showed a gradual increase in relative amygdala volume across the lifespan. Unexpectedly, tolerant species exhibited a decrease in relative amygdala volume across the lifespan, contrasting with the age-related increase observed in intolerant species—a developmental pattern previously undescribed in primates. Taken together, these findings provide valuable insights into the cognitive, neuroanatomical, and evolutionary basis of primates’ social behaviors.
Reproduced under the paper's license (CC BY), from the paper cited above.
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Data
Datasets cited
Data availability
The data associated with this study are available at: https://
The following dataset was generated:
Lamy J. 2025. Neuroanatomical Foundations of Macaques’ Social Tolerance: Insights from Subcortical Structures. Open Science Framework.
Reproduced under the paper's license (CC BY), from the paper cited above.
Versions
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Version 1, 30 September 2026: the first record
Recorded: type, language, journal, volume, pages, dates, 6 authors, 2 keywords, 9 MeSH terms, 4 funders, 123 references.
Cite
This paper
Silvere, S., Lamy, J., Po, C., Legrand, M., Sallet, J., & Ballesta, S. (2026). Toward neuroanatomical and cognitive foundations of macaque social tolerance grades. eLife, 14, RP106424. https://
BibTeX
@article{silvere2026towa
author = {Silvere, Sarah and Lamy, Julien and Po, Chrystelle and Legrand, Mathieu and Sallet, Jerome and Ballesta, Sebastien},
title = {{Toward neuroanatomical and cognitive foundations of macaque social tolerance grades}},
journal = {eLife},
year = {2026},
month = mar,
volume = {14},
pages = {RP106424},
publisher = {eLife Sciences Publications, Ltd},
issn = {2050-084X},
doi = {10.7554/
url = {https://
pmid = {41772958},
pmcid = {PMC12956280}
}
RIS
TY - JOUR
AU - Silvere, Sarah
AU - Lamy, Julien
AU - Po, Chrystelle
AU - Legrand, Mathieu
AU - Sallet, Jerome
AU - Ballesta, Sebastien
TI - Toward neuroanatomical and cognitive foundations of macaque social tolerance grades
T2 - eLife
J2 - Elife
PY - 2026
DA - 2026/
VL - 14
SP - RP106424
SN - 2050-084X
PB - eLife Sciences Publications, Ltd
DO - 10.7554/
UR - https://
LA - en
ER -
CSL-JSON
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