Cdk7 promotes neuritogenesis in cortical neurons and contributes to social behavior in mice.

OverviewAuthors: Sébastien Verteneuil1,2, Laura Van Hees3, Jean-Marc Lassance4, Camille Lejon1,2, Tine D’aes1, Quentin Marlier1, Pascale Quatresooz2, Laurence Delacroix1, Laurent Nguyen3, Brigitte Malgrange1, Renaud Vandenbosch1,2
ORCID iDs: Brigitte Malgrange, Renaud Vandenbosch
Laboratory of Developmental Neurobiology, GIGA Institute, University of Liège, Liège, 4000 Belgium
Division of Histology, Department of Biomedical and Preclinical Sciences, University of Liège, Liège, 4000 Belgium
Laboratory of Molecular Regulation of Neurogenesis, GIGA Institute, University of Liège, Liège, 4000 Belgium
Laboratory of Evolutionary Neuroethology, GIGA Institute, University of Liège, Liège, 4000 Belgium
Institutions: University of Liège (Belgium)
Journal: Cellular and molecular life sciences : CMLS, volume 83, issue 1, article 274
Dates: received 9 May 2025; accepted 1 January 2026; published online 19 May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1007/s00018-026-06139-8 · PMID 42154236 · PMCID PMC13350628 · OpenAlex W7161632870
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: mouse (organism), cellular / molecular (subfield)
Methods: Spectral & time-frequency, Statistics, Preprocessing, Evoked potentials, Connectivity, Complexity, fMRI & imaging
Keywords: Cortical Neurons, Cdks, Neuronal morphology
MeSH: Cerebral Cortex*, Cyclin-Dependent Kinases*, Neurites*, Neurogenesis*, Neurons*, Social Behavior*, Animals, Cells, Cultured, Cyclin-Dependent Kinase-Activating Kinase, Mice, Mice, Knockout, Neurodevelopment, Wnt-5a Protein (* major topic)
Topic: Cancer-related Molecular Pathways (Oncology, Medicine), according to OpenAlex
Funding: Fonds Léon Fredericq (FLF005); Fonds De La Recherche Scientifique - FNRS (R.FNRS.4347, R.FNRS.4918); Fonds pour la Formation à la Recherche dans l’Industrie et dans l’Agriculture (ASP-001)
Citations: not cited yet (Europe PMC); 82 references in the paper
Research resources: rabbit anti-NeuN 1:500 RRID:AB_10807945, 555 donkey anti-rabbit RRID:AB_162543, rat anti-Ctip2 1:500 RRID:AB_2064130, goat anti-Cux1 1:100 RRID:AB_2087003, rabbit anti-cyclin H 1:500 RRID:AB_2244347, 488 donkey anti-chicken RRID:AB_2340375, 647 donkey anti-rat RRID:AB_2340694, 488 donkey anti-rabbit RRID:AB_2535792, 555 donkey anti-goat RRID:AB_2535853, 555 donkey anti-mouse RRID:AB_2536180, 647 donkey anti-rabbit RRID:AB_2536183, RRID:AB_2536527, anti-rabbit 1:5000 RRID:AB_2536530, RRID:AB_262011, chicken anti-GFP 1:1000 RRID:AB_300798, mouse anti-Cdk7 1:500 RRID:AB_627243
AbstractThe abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

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Data

Datasets cited

geo:GSE314177, at NCBI GEO; found in the text, “RNA sequencing”

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Read it in the paper: doi.org/10.1007/s00018-026-06139-8.

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Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 11 authors, 3 keywords, 13 MeSH terms, 3 funders, 81 references, 16 RRIDs.

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This paper

Verteneuil, S., Van Hees, L., Lassance, J.-M., Lejon, C., D’aes, T., Marlier, Q., Quatresooz, P., Delacroix, L., Nguyen, L., Malgrange, B., & Vandenbosch, R. (2026). Cdk7 promotes neuritogenesis in cortical neurons and contributes to social behavior in mice. Cellular and molecular life sciences : CMLS, 83(1), 274. https://doi.org/10.1007/s00018-026-06139-8

BibTeX

@article{verteneuil2026cdk7, author = {Verteneuil, Sébastien and Van Hees, Laura and Lassance, Jean-Marc and Lejon, Camille and D’aes, Tine and Marlier, Quentin and Quatresooz, Pascale and Delacroix, Laurence and Nguyen, Laurent and Malgrange, Brigitte and Vandenbosch, Renaud}, title = {{Cdk7 promotes neuritogenesis in cortical neurons and contributes to social behavior in mice}}, journal = {Cellular and molecular life sciences : CMLS}, year = {2026}, month = may, volume = {83}, number = {1}, pages = {274}, publisher = {Springer}, issn = {1420-682X}, doi = {10.1007/s00018-026-06139-8}, url = {https://doi.org/10.1007/s00018-026-06139-8}, pmid = {42154236}, pmcid = {PMC13350628} }

RIS

TY - JOUR AU - Verteneuil, Sébastien AU - Van Hees, Laura AU - Lassance, Jean-Marc AU - Lejon, Camille AU - D’aes, Tine AU - Marlier, Quentin AU - Quatresooz, Pascale AU - Delacroix, Laurence AU - Nguyen, Laurent AU - Malgrange, Brigitte AU - Vandenbosch, Renaud TI - Cdk7 promotes neuritogenesis in cortical neurons and contributes to social behavior in mice T2 - Cellular and molecular life sciences : CMLS J2 - Cell Mol Life Sci PY - 2026 DA - 2026/05/19 VL - 83 IS - 1 SP - 274 SN - 1420-682X PB - Springer DO - 10.1007/s00018-026-06139-8 UR - https://doi.org/10.1007/s00018-026-06139-8 LA - en ER -

CSL-JSON

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