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From relapse to survival: real-world clinical impact of a multimodal approach in first-time recurrent glioblastoma : FROST: multimodal treatment for GBM recurrence.

Overview

Authors: Jean-Baptiste Barbe-Richaud1, Hélène Cebula2, Julien Todeschi2, Marie des Neiges Santin2, Seyyid Baloglu3, Roland Schott1, Mathieu Cotton4, Aurélien Blouet5, Maxime Bobin5, Georges Noël6, Laura Somme1
  1. Oncology Department, Institut de Cancérologie Strasbourg Europe,17 Rue Albert Calmette, Strasbourg, 67200 France
  2. Neurosurgery Department, Hôpitaux Universitaires de Strasbourg,1 Avenue Molière, Strasbourg, 67200 France
  3. Neuro-Radiology Department, Hôpitaux Universitaires de Strasbourg,1 Avenue Molière, Strasbourg, 67200 France
  4. Pharmaceutic Department, Institut de Cancérologie Strasbourg Europe,17 Rue Albert Calmette, Strasbourg, 67200 France
  5. Radiotherapy Department, Centre d’Oncologie du Pays Basque, 83 Avenue du 14 Avril 1814, Bayonne, 64100 France
  6. Radiotherapy Department, Institut de Cancérologie Strasbourg Europe,17 Rue Albert Calmette, Strasbourg, 67200 France
Journal: Journal of neuro-oncology, volume 178, issue 3, article 73
Dates: received 20 March 2026; accepted 14 May 2026; published online 23 June 2026; in print 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1007/s11060-026-05635-y · PMID 42334687 · PMCID PMC13290778 · OpenAlex W7165535027
Open access: hybrid, a free copy (OpenAlex)
Status: code on request
Categories: human (organism), other condition (population), clinical / translational (subfield)
Methods: Statistics
Keywords: Glioblastoma, Recurrence, Chemotherapy, Radiotherapy, Surgery, Multimodal
MeSH: Brain Neoplasms*, Glioblastoma*, Neoplasm Recurrence, Local*, Adult, Aged, Antineoplastic Agents, Alkylating, Chemoradiotherapy, Combined Modality Therapy, Female, Follow-Up Studies, Humans, Male, Middle Aged, Retrospective Studies, Temozolomide (* major topic)
Topic: Glioma Diagnosis and Treatment (Genetics, Medicine), according to OpenAlex
Citations: not cited yet (Europe PMC); 49 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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The paper's code and data availability statement is in the Data section.

Tracing map

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Data

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Code and data availability statement

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  • it says that the data are available on request
  • it says that the code is available on request

Read it in the paper: doi.org/10.1007/s11060-026-05635-y.

Versions

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Version 2, 28 September 2026

  • Publisher: n/a → Springer Science+Business Media

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 11 authors, 6 keywords, 15 MeSH terms, 49 references.

Cite

This paper

Barbe-Richaud, J.-B., Cebula, H., Todeschi, J., Santin, M. d. N., Baloglu, S., Schott, R., Cotton, M., Blouet, A., Bobin, M., Noël, G., & Somme, L. (2026). From relapse to survival: real-world clinical impact of a multimodal approach in first-time recurrent glioblastoma : FROST: multimodal treatment for GBM recurrence. Journal of neuro-oncology, 178(3), 73. https://doi.org/10.1007/s11060-026-05635-y

BibTeX

@article{barberichaud2026relapse,
author = {Barbe-Richaud, Jean-Baptiste and Cebula, Hélène and Todeschi, Julien and Santin, Marie des Neiges and Baloglu, Seyyid and Schott, Roland and Cotton, Mathieu and Blouet, Aurélien and Bobin, Maxime and Noël, Georges and Somme, Laura},
title = {{From relapse to survival: real-world clinical impact of a multimodal approach in first-time recurrent glioblastoma : FROST: multimodal treatment for GBM recurrence}},
journal = {Journal of neuro-oncology},
year = {2026},
month = jun,
volume = {178},
number = {3},
pages = {73},
publisher = {Springer Science+Business Media},
issn = {0167-594X},
doi = {10.1007/s11060-026-05635-y},
url = {https://doi.org/10.1007/s11060-026-05635-y},
pmid = {42334687},
pmcid = {PMC13290778}
}

RIS

TY - JOUR
AU - Barbe-Richaud, Jean-Baptiste
AU - Cebula, Hélène
AU - Todeschi, Julien
AU - Santin, Marie des Neiges
AU - Baloglu, Seyyid
AU - Schott, Roland
AU - Cotton, Mathieu
AU - Blouet, Aurélien
AU - Bobin, Maxime
AU - Noël, Georges
AU - Somme, Laura
TI - From relapse to survival: real-world clinical impact of a multimodal approach in first-time recurrent glioblastoma : FROST: multimodal treatment for GBM recurrence
T2 - Journal of neuro-oncology
J2 - J Neurooncol
PY - 2026
DA - 2026/06/23
VL - 178
IS - 3
SP - 73
SN - 0167-594X
PB - Springer Science+Business Media
DO - 10.1007/s11060-026-05635-y
UR - https://doi.org/10.1007/s11060-026-05635-y
LA - en
ER -

CSL-JSON

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"container-title": "Journal of neuro-oncology",
"author": [
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"family": "Barbe-Richaud",
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"container-title-short": "J Neurooncol",
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