OSCR

Generation and Validation of an Acan-Cre Mouse Line to Selectively Label Class-B Excitatory Neurons of the Cerebellar Nuclei.

Overview

Authors: Julian Cheron1, Maggie Lowman1, Manjari M-G Anant2,3,4, Max Siauw1, Justus M Kebschull1,2,3,5
  1. Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205 USA
  2. Department of Neuroscience, Johns Hopkins University, Baltimore, MD 21205 USA
  3. Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD 21205 USA
  4. Center for Computational Biology, Johns Hopkins University, Baltimore, MD 21205 USA
  5. Center for Functional Anatomy and Evolution, Johns Hopkins University, Baltimore, MD 21205 USA
Institutions: Johns Hopkins University (United States)
Journal: Cerebellum (London, England), volume 25, issue 5, article 125
Dates: received 21 May 2026; accepted 6 August 2026; published online 12 August 2026; in print 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1007/s12311-026-02068-1 · PMID 42584780 · PMCID PMC13469396 · OpenAlex W7162215198
Open access: hybrid, a free copy (OpenAlex)
Preprint: doi:10.64898/2026.05.21.726923
Status: dead link
Categories: mouse (organism), cellular / molecular (subfield)
Methods: Evoked potentials
Keywords: Cerebellar nuclei, Class-B cells, Acan, Cell types
MeSH: Cerebellar Nuclei*, Neurons*, Animals, Integrases, Mice, Mice, Inbred C57BL, Mice, Transgenic (* major topic)
Topic: Vestibular and auditory disorders (Neurology, Neuroscience), according to OpenAlex
Funding: Friedreich's Ataxia Research Alliance
Citations: not cited yet (Europe PMC); 25 references in the paper
Research resources: RRID:AB_142924, RRID:AB_2534023, We purchased C57Bl6/J RRID:IMSR_JAX:000664, Slc17a6-Cre RRID:IMSR_JAX:016963

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

No file of the authors' code could be read here: it is described below, and read at its source.

kebschulllab/Acan-Cre-cerebellar-nucleiBARseq3

License: none: the authors keep all their rights
State: the link is dead, verified on 27 September 2026
Evidence: found in the paper
Software Heritage: not archived
Found in: “Data Availability”
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 27 September 2026: the link is dead
  • 27 September 2026: the link is dead
At the source: github.com/kebschulllab/Acan-Cre-cerebellar-nucleiBARseq3

The paper's code and data availability statement is in the Data section.

Tracing map

Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.

What the map holds:

  • 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
  • 0 scripts, each with its path and the digest of its content;
  • no match between paragraphs and code yet;
  • neither the text of the paper nor the code itself.

Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

Datasets cited

Code and data availability statement

The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

Read it in the paper: doi.org/10.1007/s12311-026-02068-1.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 3, 28 September 2026

  • Publisher: n/a → Springer Science+Business Media
  • Funding: added Friedreich's Ataxia Research Alliance

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 5 authors, 4 keywords, 7 MeSH terms, 25 references, 4 RRIDs.

Cite

This paper

Cheron, J., Lowman, M., M-G Anant, M., Siauw, M., & Kebschull, J. M. (2026). Generation and Validation of an Acan-Cre Mouse Line to Selectively Label Class-B Excitatory Neurons of the Cerebellar Nuclei. Cerebellum (London, England), 25(5), 125. https://doi.org/10.1007/s12311-026-02068-1

BibTeX

@article{cheron2026generation,
author = {Cheron, Julian and Lowman, Maggie and M-G Anant, Manjari and Siauw, Max and Kebschull, Justus M},
title = {{Generation and Validation of an Acan-Cre Mouse Line to Selectively Label Class-B Excitatory Neurons of the Cerebellar Nuclei}},
journal = {Cerebellum (London, England)},
year = {2026},
month = aug,
volume = {25},
number = {5},
pages = {125},
publisher = {Springer Science+Business Media},
issn = {1473-4222},
doi = {10.1007/s12311-026-02068-1},
url = {https://doi.org/10.1007/s12311-026-02068-1},
pmid = {42584780},
pmcid = {PMC13469396}
}

RIS

TY - JOUR
AU - Cheron, Julian
AU - Lowman, Maggie
AU - M-G Anant, Manjari
AU - Siauw, Max
AU - Kebschull, Justus M
TI - Generation and Validation of an Acan-Cre Mouse Line to Selectively Label Class-B Excitatory Neurons of the Cerebellar Nuclei
T2 - Cerebellum (London, England)
J2 - Cerebellum
PY - 2026
DA - 2026/08/12
VL - 25
IS - 5
SP - 125
SN - 1473-4222
PB - Springer Science+Business Media
DO - 10.1007/s12311-026-02068-1
UR - https://doi.org/10.1007/s12311-026-02068-1
LA - en
ER -

CSL-JSON

{
"id": "10.1007/s12311-026-02068-1",
"type": "article-journal",
"title": "Generation and Validation of an Acan-Cre Mouse Line to Selectively Label Class-B Excitatory Neurons of the Cerebellar Nuclei",
"container-title": "Cerebellum (London, England)",
"author": [
{
"family": "Cheron",
"given": "Julian"
},
{
"family": "Lowman",
"given": "Maggie"
},
{
"family": "M-G Anant",
"given": "Manjari"
},
{
"family": "Siauw",
"given": "Max"
},
{
"family": "Kebschull",
"given": "Justus M"
}
],
"container-title-short": "Cerebellum",
"volume": "25",
"issue": "5",
"page": "125",
"DOI": "10.1007/s12311-026-02068-1",
"PMID": "42584780",
"PMCID": "PMC13469396",
"ISSN": "1473-4222",
"publisher": "Springer Science+Business Media",
"URL": "https://doi.org/10.1007/s12311-026-02068-1",
"language": "en",
"issued": {
"date-parts": [
[
2026,
8,
12
]
]
}
}

The tracing map gets a citation of its own once an author has validated it and it has a DOI.

Similar papers

The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.

[1] doi:10.1038/s42003-026-10034-0 [code]
Region- and cell type-specific changes in gene expression in the cerebellum after classical fear conditioning.
Journal: Communications biology
In common: mouse, cellular / molecular, 4 references
[2] doi:10.1038/s41467-026-75650-0 [code]
Reduced melanocortin tone modulates feeding during pregnancy in mice.
Journal: Nature communications
In common: mouse, 2 references
[3] doi:10.1111/jnc.70503
Astrocytic Regulation of Aberrant Perineuronal Net Formation in Mecp2-Null Neocortex.
Journal: Journal of neurochemistry
In common: mouse, cellular / molecular, 1 reference
[4] doi:10.1038/s41586-026-10512-9 [code]
Astrocyte glucocorticoid receptor signalling restricts neuronal plasticity.
Journal: Nature
In common: mouse, cellular / molecular, 1 reference
[5] doi:10.1016/j.celrep.2026.117298 [code]
Midbrain endocannabinoids actuate dopamine-based action selection.
Journal: Cell reports
In common: mouse, cellular / molecular, 1 reference
[6] doi:10.1038/s41586-026-10629-x [code]
Whole-genome duplication shaped cell-type evolution in the vertebrate brain.
Journal: Nature
In common: mouse, cellular / molecular, 1 reference
[7] doi:10.1038/s41398-026-03952-4 [code]
Perineuronal nets in cerebellar nuclei neurons orchestrate social behaviour via regulation of neuronal activity in circuits innervated by the cerebellum.
Journal: Translational psychiatry
In common: mouse, cellular / molecular, 1 reference
[8] doi:10.1016/j.molmet.2026.102403 [code]
The central amygdala gates exogenous glucagon-like peptide 1 signals.
Journal: Molecular metabolism
In common: mouse, cellular / molecular, 1 reference
[9] doi:10.7554/elife.93664 [code]
Drug-induced changes in connectivity to midbrain dopamine cells revealed by rabies monosynaptic tracing.
Journal: eLife
In common: mouse, cellular / molecular, 1 reference
[10] doi:10.1016/j.celrep.2026.117262 [code]
Cerebellar acceleration of learning in an evidence-accumulation task.
Journal: Cell reports
In common: mouse, 1 reference

Contribute

The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.

Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.

Request its removal

To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).

Discussion, reproductions, activity

Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.

Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.

Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.