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Circulating palmitoleic acid is associated with cerebral glucose metabolism in healthy middle-aged individuals: results from the Progression of Early Subclinical Atherosclerosis prospective cohort study.

Overview

Authors: Aleix Sala-Vila1,2,3, Catarina Tristão-Pereira4,5, Iolanda Lázaro1,3, Mehrnaz Shekari1,6, Alberto Fernández-Pena4, Jennifer Monereo-Sánchez4, Ines Garcia-Lunar4,7,8, Cristina Perez-Herreras9, Maria Angeles Moro4, Ana Garcia-Alvarez4,8,10, Javier Sanchez-Gonzalez11, Juan Domingo Gispert4,6, Borja Ibanez4,8,12, Valentin Fuster4,13, Marta Cortes-Canteli4,14
14 affiliations
  1. Group of Cardiovascular Risk and Nutrition, Hospital del Mar Research Institute, Barcelona, Spain
  2. Fatty Acid Research Institute (FARI), Sioux Falls, SD, USA
  3. Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain
  4. Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain
  5. Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
  6. Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain
  7. Cardiology Department, University Hospital La Moraleja, Madrid, Spain
  8. Centro de Investigación Biomédica en Red de de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III (ISCIII), Madrid, Spain
  9. Santander Bank, Madrid, Spain
  10. Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain
  11. Philips Healthcare Iberia, Madrid, Spain
  12. Health Research Institute, Fundación Jiménez Díaz University Hospital, Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain
  13. Icahn School of Medicine at Mount Sinai, New York, NY, USA
  14. Centro de Neurociencias Cajal-Consejo Superior de Investigaciones Científicas (CNC-CSIC), Madrid, Spain
Journal: The American journal of clinical nutrition, volume 124, issue 2, article 101392
Dates: received 10 March 2026; accepted 5 June 2026; published online 10 June 2026; in print August 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.ajcnut.2026.101392 · PMID 42269969 · PMCID PMC13494094 · OpenAlex W7164190122
Open access: hybrid, a free copy (OpenAlex)
Status: code on request
Categories: PET / SPECT (modality), human (organism), clinical / translational (subfield)
Methods: Statistics, fMRI & imaging
Keywords: diet, brain health, neuroimaging, energy metabolism, biomarkers
MeSH: Atherosclerosis*, Brain*, Fatty Acids, Monounsaturated*, Glucose*, Biomarkers, Cross-Sectional Studies, Female, Humans, Longitudinal Studies, Male, Middle Aged, Positron-Emission Tomography, Prospective Studies (* major topic)
Topic: Diet and metabolism studies (Physiology, Medicine), according to OpenAlex
Funding: Centro Nacional de Investigaciones Cardiovasculares (CNIC); Santander Bank; European Regional Development Fund; European Social Fund
Citations: not cited yet (Europe PMC); 43 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Code and data availability statement

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Read it in the paper: doi.org/10.1016/j.ajcnut.2026.101392.

Versions

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Version 2, 28 September 2026

  • Authors: added Marta Cortes-Canteli (0000-0001-8802-4338); removed Marta Cortes-Canteli

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 15 authors, 5 keywords, 13 MeSH terms, 4 funders, 43 references.

Cite

This paper

Sala-Vila, A., Tristão-Pereira, C., Lázaro, I., Shekari, M., Fernández-Pena, A., Monereo-Sánchez, J., Garcia-Lunar, I., Perez-Herreras, C., Moro, M. A., Garcia-Alvarez, A., Sanchez-Gonzalez, J., Gispert, J. D., Ibanez, B., Fuster, V., & Cortes-Canteli, M. (2026). Circulating palmitoleic acid is associated with cerebral glucose metabolism in healthy middle-aged individuals: results from the Progression of Early Subclinical Atherosclerosis prospective cohort study. The American journal of clinical nutrition, 124(2), 101392. https://doi.org/10.1016/j.ajcnut.2026.101392

BibTeX

@article{salavila2026circulating,
author = {Sala-Vila, Aleix and Tristão-Pereira, Catarina and Lázaro, Iolanda and Shekari, Mehrnaz and Fernández-Pena, Alberto and Monereo-Sánchez, Jennifer and Garcia-Lunar, Ines and Perez-Herreras, Cristina and Moro, Maria Angeles and Garcia-Alvarez, Ana and Sanchez-Gonzalez, Javier and Gispert, Juan Domingo and Ibanez, Borja and Fuster, Valentin and Cortes-Canteli, Marta},
title = {{Circulating palmitoleic acid is associated with cerebral glucose metabolism in healthy middle-aged individuals: results from the Progression of Early Subclinical Atherosclerosis prospective cohort study}},
journal = {The American journal of clinical nutrition},
year = {2026},
month = jun,
volume = {124},
number = {2},
pages = {101392},
publisher = {American Society for Nutrition},
issn = {0002-9165},
doi = {10.1016/j.ajcnut.2026.101392},
url = {https://doi.org/10.1016/j.ajcnut.2026.101392},
pmid = {42269969},
pmcid = {PMC13494094}
}

RIS

TY - JOUR
AU - Sala-Vila, Aleix
AU - Tristão-Pereira, Catarina
AU - Lázaro, Iolanda
AU - Shekari, Mehrnaz
AU - Fernández-Pena, Alberto
AU - Monereo-Sánchez, Jennifer
AU - Garcia-Lunar, Ines
AU - Perez-Herreras, Cristina
AU - Moro, Maria Angeles
AU - Garcia-Alvarez, Ana
AU - Sanchez-Gonzalez, Javier
AU - Gispert, Juan Domingo
AU - Ibanez, Borja
AU - Fuster, Valentin
AU - Cortes-Canteli, Marta
TI - Circulating palmitoleic acid is associated with cerebral glucose metabolism in healthy middle-aged individuals: results from the Progression of Early Subclinical Atherosclerosis prospective cohort study
T2 - The American journal of clinical nutrition
J2 - Am J Clin Nutr
PY - 2026
DA - 2026/06/10
VL - 124
IS - 2
SP - 101392
SN - 0002-9165
PB - American Society for Nutrition
DO - 10.1016/j.ajcnut.2026.101392
UR - https://doi.org/10.1016/j.ajcnut.2026.101392
LA - en
ER -

CSL-JSON

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