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A neuropeptide regulates cell non-autonomous protein homeostasis.

Overview

Authors: Carrie A. Sheeler1, Jacqueline Y. Lo2, Areebah Rahman1, Saebom Kwon1, Daviana Menendez Escalera1, Emmett Griffin-Baldwin1, Karmen Mah1, Adam Roszczyk1, Jennifer L. Garrison2, Ashley E. Frakes1,3,4
  1. Genetics and Biochemistry Branch, NIDDK, National Institutes of Health, Bethesda, MD 20814, USA
  2. Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, CA 94945, USA
  3. National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD, USA
  4. Lead contact
Journal: Cell reports, volume 45, issue 4, article 117207
Dates: published online 30 March 2026; in print March 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.celrep.2026.117207 · PMID 41915471 · PMCID PMC13220339 · OpenAlex W7143405243
Open access: gold, a free copy (OpenAlex)
Status: code on request (how the code is found and verified)
Categories: C. elegans (organism), cellular / molecular (subfield)
Methods: Statistics, Evoked potentials, fMRI & imaging
Keywords: Neurons, Neuropeptides, Endoplasmic reticulum, Unfolded protein response, ER stress, Glia, C. Elegans, Protein Homeostasis, Cellular Stress Responses, Cp: Cell Biology, Cell Non-autonomous Cellular Signaling
Topic: Neuropeptides and Animal Physiology (Cellular and Molecular Neuroscience, Neuroscience), according to OpenAlex
Funding: National Heart, Lung, and Blood Institute; National Institute of Diabetes and Digestive and Kidney Diseases (1ZIADK075172, R35 GM145305, T32 AG000266); NIGMS NIH HHS (R35 GM145305); National Institutes of Health; NIA NIH HHS (T32 AG000266); Glenn Foundation for Medical Research; U.S. Department of Health and Human Services; Intramural NIH HHS (Z99 DK999999, ZIA DK075172)
Citations: not cited yet (Europe PMC); 48 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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The paper's code and data availability statement is in the Data section.

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Data

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Code and data availability statement

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  • it says that the data are available on request
  • it says that the code is available on request

Read it in the paper: doi.org/10.1016/j.celrep.2026.117207.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 10 authors, 11 keywords, 8 funders, 47 references.

Cite

This paper

Sheeler, C. A., Lo, J. Y., Rahman, A., Kwon, S., Escalera, D. M., Griffin-Baldwin, E., Mah, K., Roszczyk, A., Garrison, J. L., & Frakes, A. E. (2026). A neuropeptide regulates cell non-autonomous protein homeostasis. Cell reports, 45(4), 117207. https://doi.org/10.1016/j.celrep.2026.117207

BibTeX

@article{sheeler2026neuropeptide,
author = {Sheeler, Carrie A. and Lo, Jacqueline Y. and Rahman, Areebah and Kwon, Saebom and Escalera, Daviana Menendez and Griffin-Baldwin, Emmett and Mah, Karmen and Roszczyk, Adam and Garrison, Jennifer L. and Frakes, Ashley E.},
title = {{A neuropeptide regulates cell non-autonomous protein homeostasis}},
journal = {Cell reports},
year = {2026},
month = mar,
volume = {45},
number = {4},
pages = {117207},
publisher = {Cell Press},
issn = {2211-1247},
doi = {10.1016/j.celrep.2026.117207},
url = {https://doi.org/10.1016/j.celrep.2026.117207},
pmid = {41915471},
pmcid = {PMC13220339}
}

RIS

TY - JOUR
AU - Sheeler, Carrie A.
AU - Lo, Jacqueline Y.
AU - Rahman, Areebah
AU - Kwon, Saebom
AU - Escalera, Daviana Menendez
AU - Griffin-Baldwin, Emmett
AU - Mah, Karmen
AU - Roszczyk, Adam
AU - Garrison, Jennifer L.
AU - Frakes, Ashley E.
TI - A neuropeptide regulates cell non-autonomous protein homeostasis
T2 - Cell reports
J2 - Cell Rep
PY - 2026
DA - 2026/03/30
VL - 45
IS - 4
SP - 117207
SN - 2211-1247
PB - Cell Press
DO - 10.1016/j.celrep.2026.117207
UR - https://doi.org/10.1016/j.celrep.2026.117207
LA - en
ER -

CSL-JSON

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"ISSN": "2211-1247",
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"language": "en",
"issued": {
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