A single-echo/multi-echo BOLD fMRI test-retest dataset.
Overview
- Penn Lifespan Informatics and Neuroimaging Center, Richards Research Labs, 5th Floor, 3700 Hamilton Walk, University of Pennsylvania, Philadelphia, PA, 19104, USA
- Department of Psychiatry, Perelman School of Medicine, 3535 Market Street, University of Pennsylvania, PA, 19104, USA
- Penn-CHOP Lifespan Brain Institute, Perelman School of Medicine, 3400 Spruce St., Gates Pavilion, 10th Floor, Neurodevelopment and Psychosis Section, Children’s Hospital of Philadelphia, PA, 19104, USA
- Department of Child and Adolescent Psychiatry and Behavioral Science, 3401 Civic Center Boulevard, Children’s Hospital of Philadelphia, Philadelphia, PA, 19104, USA
- Department of Radiology, Perelman School of Medicine, 3400 Spruce Street, University of Pennsylvania, Philadelphia, PA, 19104, USA
Abstract
Functional MRI (fMRI) remains one of the primary tools for non-invasive studies of brain activity and organization in humans. Recently, multi-echo imaging has generated interest due to the improved signal-to-noise and potential for superior denoising. In parallel, developments in MRI processing techniques, such as the use of phase data and advanced denoising methods, have continued to advance the field. An important step towards adopting these methodologies is directly comparing them to existing techniques using real-world data. We present a neuroimaging dataset that allows for within-subject comparison of single-echo vs multi-echo imaging with cutting-edge imaging acquisition parameters such as magnitude and phase reconstruction and no-excitation (noise only) volumes. The sample includes test-retest data from eight young adults. Each session includes a T1-weighted anatomical scan, four resting-state functional MRI scans (two each for single-echo and complex multi-echo), and a multi-echo task-based functional MRI scan from a fractal n-back working memory task. Raw imaging files are released, as well as derivatives from our open-source processing pipelines. These rich data provide opportunities for direct comparison of single-echo and multi-echo methodologies. Moving forward, the data facilitate studies of evaluating how advanced image acquisition and processing impact test-retest reliability.
Reproduced under the paper's license (CC BY-NC), from the paper cited above.
Code
The paper links to its data, not to its authors' code: see the Data section.
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Data
Datasets cited
- doi:10.18112/
openneuro.ds007637.v1.0. , at OpenNeuro; found in the references0 - neurovault.org/
collections/ , at neurovault.org; found in “Data availability”23719 - openneuro:ds007637, at OpenNeuro; found in the text
Data availability
OpenNeuroSingle-echo/
Reproduced under the paper's license (CC BY-NC), from the paper cited above.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 2, 28 September 2026
- Authors: added Manuel Taso (0000-0003-2405-9165); M. Dylan Tisdall (0000-0002-0454-3112); David R. Roalf (0000-0002-1728-9782); Theodore D. Satterthwaite (0000-0001-7072-9399); removed Manuel Taso; M. Dylan Tisdall; David R. Roalf; Theodore D. Satterthwaite
Version 1, 27 September 2026: the first record
Recorded: type, language, journal, volume, pages, dates, 12 authors, 6 keywords, 2 funders, 20 references.
Cite
This paper
Salo, T., Singleton, S. P., Horien, C., Cieslak, M., Flook, E. A., Rush, S., Sevchik, B. L., Tong, T. T., Taso, M., Tisdall, M. D., Roalf, D. R., & Satterthwaite, T. D. (2026). A single-echo/
BibTeX
@article{salo2026single,
author = {Salo, Taylor and Singleton, S. Parker and Horien, Corey and Cieslak, Matthew and Flook, Elizabeth A. and Rush, Sage and Sevchik, Brooke L. and Tong, Tien T. and Taso, Manuel and Tisdall, M. Dylan and Roalf, David R. and Satterthwaite, Theodore D.},
title = {{A single-echo/
journal = {Data in brief},
year = {2026},
month = jul,
volume = {67},
pages = {113056},
publisher = {Elsevier},
issn = {2352-3409},
doi = {10.1016/
url = {https://
pmid = {42434500},
pmcid = {PMC13351147}
}
RIS
TY - JOUR
AU - Salo, Taylor
AU - Singleton, S. Parker
AU - Horien, Corey
AU - Cieslak, Matthew
AU - Flook, Elizabeth A.
AU - Rush, Sage
AU - Sevchik, Brooke L.
AU - Tong, Tien T.
AU - Taso, Manuel
AU - Tisdall, M. Dylan
AU - Roalf, David R.
AU - Satterthwaite, Theodore D.
TI - A single-echo/
T2 - Data in brief
J2 - Data Brief
PY - 2026
DA - 2026/
VL - 67
SP - 113056
SN - 2352-3409
PB - Elsevier
DO - 10.1016/
UR - https://
LA - en
ER -
CSL-JSON
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