OSCR

Decoding unchanged transcriptome of Alzheimer's disease reveals an NCAM1 mRNA switch as a potential biomarker.

Overview

Authors: Haotian Li1, Sai Liu1, Daoxin Miao1, Long Chen1, Yuan Sun1, Guangji Wang1, Zheying Zhu2, Xinuo Li1, Qiulun Lu1
ORCID iDs: Qiulun Lu
  1. State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, China
  2. School of Pharmacy, The University of Nottingham, NG72RD Nottingham, UK
Institutions: China Pharmaceutical University (China); State Key Laboratory of Natural Medicine (China); University of Nottingham (United Kingdom)
Journal: iScience, volume 29, issue 4, article 115456
Dates: received 15 September 2025; accepted 19 March 2026; published online 26 March 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.isci.2026.115456 · PMID 42006342 · PMCID PMC13090632 · OpenAlex W7140679970
Open access: gold, a free copy (OpenAlex)
Status: data only (how the code is found and verified)
Categories: genetics / omics (modality), mouse (organism), Alzheimer's / dementia (population)
Methods: Connectivity, Statistics, Smoothing, state filtering, decompositions
Keywords: Health sciences, Neuroscience, Molecular neuroscience, Clinical neuroscience, Cellular neuroscience
Topic: Alzheimer's disease research and treatments (Cellular and Molecular Neuroscience, Neuroscience), according to OpenAlex
Funding: China Postdoctoral Science Foundation (2024 T171037); National Natural Science Foundation of China (BK20221051); Sanming Project of Medicine in Shenzhen (SZSM201801060); Foundation Research Project of Jiangsu Province
Citations: not cited yet (Europe PMC); 73 references in the paper
Research resources: Rabbit polyclonal anti-NCAM1/CD56 RRID:AB_2149421

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Code and data availability statement

The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the data are available on request

Read it in the paper: doi.org/10.1016/j.isci.2026.115456.

Versions

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Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 9 authors, 5 keywords, 4 funders, 73 references, 1 RRID.

Cite

This paper

Li, H., Liu, S., Miao, D., Chen, L., Sun, Y., Wang, G., Zhu, Z., Li, X., & Lu, Q. (2026). Decoding unchanged transcriptome of Alzheimer's disease reveals an NCAM1 mRNA switch as a potential biomarker. iScience, 29(4), 115456. https://doi.org/10.1016/j.isci.2026.115456

BibTeX

@article{li2026decoding,
author = {Li, Haotian and Liu, Sai and Miao, Daoxin and Chen, Long and Sun, Yuan and Wang, Guangji and Zhu, Zheying and Li, Xinuo and Lu, Qiulun},
title = {{Decoding unchanged transcriptome of Alzheimer's disease reveals an NCAM1 mRNA switch as a potential biomarker}},
journal = {iScience},
year = {2026},
month = mar,
volume = {29},
number = {4},
pages = {115456},
publisher = {Elsevier},
issn = {2589-0042},
doi = {10.1016/j.isci.2026.115456},
url = {https://doi.org/10.1016/j.isci.2026.115456},
pmid = {42006342},
pmcid = {PMC13090632}
}

RIS

TY - JOUR
AU - Li, Haotian
AU - Liu, Sai
AU - Miao, Daoxin
AU - Chen, Long
AU - Sun, Yuan
AU - Wang, Guangji
AU - Zhu, Zheying
AU - Li, Xinuo
AU - Lu, Qiulun
TI - Decoding unchanged transcriptome of Alzheimer's disease reveals an NCAM1 mRNA switch as a potential biomarker
T2 - iScience
J2 - iScience
PY - 2026
DA - 2026/03/26
VL - 29
IS - 4
SP - 115456
SN - 2589-0042
PB - Elsevier
DO - 10.1016/j.isci.2026.115456
UR - https://doi.org/10.1016/j.isci.2026.115456
LA - en
ER -

CSL-JSON

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