OSCR

Ion transport peptide regulates larval body water balance via a receptor guanylyl cyclase in <i>Drosophila</i>.

Overview

Authors: Akira Watanabe1, Takashi Koyama2, Olga Kubrak2, Michael James Texada2, Megumi Furumitsu3, Eiko Iwakoshi-Ukena3, Roilea Maxson4, Taishi Yoshii5, Shu Kondo6, Naoki Yamanaka4, Kazuyoshi Ukena3, Kim Rewitz2, Ryusuke Niwa7, Naoki Okamoto7,8
ORCID iDs: Takashi Koyama, Taishi Yoshii, Naoki Okamoto
  1. Degree Programs in Life and Earth Sciences, Graduate School of Science and Technology, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki 305-8572, Japan
  2. Department of Biology, Section for Cell and Neurobiology, University of Copenhagen, Universitetsparken 15, Building 3, Copenhagen 2100, Denmark
  3. Graduate School of Integrated Sciences for Life, Hiroshima University, Hiroshima 739-8521, Japan
  4. Department of Entomology, Institute for Integrative Genome Biology, University of California, Riverside, 900 University Ave, Riverside, CA 92521, USA
  5. Graduate School of Environmental, Life, Natural Science and Technology, Okayama University, Okayama 700-8530, Japan
  6. Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan
  7. Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki 305-8577, Japan
  8. Suntory Rising Stars Encouragement Program in Life Sciences (SunRiSE), Suntory Foundation for Life Sciences, Kyoto 619-0284, Japan
Institutions: University of Tsukuba (Japan); University of Copenhagen (Denmark); Hiroshima University (Japan); University of California, Riverside (United States); Institute for Integrative Genome Biology (United States); Okayama University (Japan); Tokyo University of Science (Japan); Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA); Suntory Foundation for Life Sciences (Japan)
Journal: iScience, volume 29, issue 6, article 116252
Dates: received 4 November 2025; accepted 20 May 2026; published online 14 June 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.isci.2026.116252 · PMID 42305610 · PMCID PMC13267572 · OpenAlex W7164754437
Open access: gold, a free copy (OpenAlex)
Status: code on request
Categories: drosophila (organism), cellular / molecular (subfield)
Methods: Statistics, Evoked potentials
Keywords: Animal physiology, Cell biology, Developmental biology
Topic: Neurobiology and Insect Physiology Research (Cellular and Molecular Neuroscience, Neuroscience), according to OpenAlex
Funding: Vienna Drosophila Resource Center; Bloomington Drosophila Stock Center; National Institute of Genetics Fly Stock Center; Kyoto Stock Center; Harvard Medical School; Write Labs; Japan Science and Technology Agency; JST; FOREST Program (JPMJFR224M); Japan Society for the Promotion of Science; JSPS (24KJ0466); KAKENHI; Grant-in-Aid for Scientific Research (B) (25K02307); Suntory Rising Stars Encouragement Program in Life Sciences; Support for Pioneering Research Initiated by the Next Generation (JPMJSP2124); Independent Research Fund Denmark; DFF (4283-00022B)
Citations: not cited yet (Europe PMC); 62 references in the paper
Research resources: RRID:AB_2534117, Goat anti-Mouse IgG, Alexa Fluor 647 RRID:AB_2535804, Goat anti-Chicken IgG, Alexa Fluor 488 RRID:AB_2762843, Chicken polyclonal anti-GFP RRID:AB_300798, RRID:AB_3348520

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper says that its authors' code is available on request: it was not published with the paper, so there is nothing to verify.

The paper's code and data availability statement is in the Data section.

Tracing map

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Data

No dataset and no data link were found in the paper.

Code and data availability statement

The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the data are available on request
  • it says that the code is available on request

Read it in the paper: doi.org/10.1016/j.isci.2026.116252.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 2, 28 September 2026

  • Authors: added Naoki Okamoto (0000-0003-2371-5060); removed Naoki Okamoto

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 14 authors, 3 keywords, 17 funders, 62 references, 5 RRIDs.

Cite

This paper

Watanabe, A., Koyama, T., Kubrak, O., Texada, M. J., Furumitsu, M., Iwakoshi-Ukena, E., Maxson, R., Yoshii, T., Kondo, S., Yamanaka, N., Ukena, K., Rewitz, K., Niwa, R., & Okamoto, N. (2026). Ion transport peptide regulates larval body water balance via a receptor guanylyl cyclase in <i>Drosophila</i>. iScience, 29(6), 116252. https://doi.org/10.1016/j.isci.2026.116252

BibTeX

@article{watanabe2026ion,
author = {Watanabe, Akira and Koyama, Takashi and Kubrak, Olga and Texada, Michael James and Furumitsu, Megumi and Iwakoshi-Ukena, Eiko and Maxson, Roilea and Yoshii, Taishi and Kondo, Shu and Yamanaka, Naoki and Ukena, Kazuyoshi and Rewitz, Kim and Niwa, Ryusuke and Okamoto, Naoki},
title = {{Ion transport peptide regulates larval body water balance via a receptor guanylyl cyclase in \<i\>Drosophila\</i\>}},
journal = {iScience},
year = {2026},
month = jun,
volume = {29},
number = {6},
pages = {116252},
publisher = {Elsevier},
issn = {2589-0042},
doi = {10.1016/j.isci.2026.116252},
url = {https://doi.org/10.1016/j.isci.2026.116252},
pmid = {42305610},
pmcid = {PMC13267572}
}

RIS

TY - JOUR
AU - Watanabe, Akira
AU - Koyama, Takashi
AU - Kubrak, Olga
AU - Texada, Michael James
AU - Furumitsu, Megumi
AU - Iwakoshi-Ukena, Eiko
AU - Maxson, Roilea
AU - Yoshii, Taishi
AU - Kondo, Shu
AU - Yamanaka, Naoki
AU - Ukena, Kazuyoshi
AU - Rewitz, Kim
AU - Niwa, Ryusuke
AU - Okamoto, Naoki
TI - Ion transport peptide regulates larval body water balance via a receptor guanylyl cyclase in <i>Drosophila</i>
T2 - iScience
J2 - iScience
PY - 2026
DA - 2026/06/14
VL - 29
IS - 6
SP - 116252
SN - 2589-0042
PB - Elsevier
DO - 10.1016/j.isci.2026.116252
UR - https://doi.org/10.1016/j.isci.2026.116252
LA - en
ER -

CSL-JSON

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}

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