OSCR

Swine reporter model for preclinical evaluation and characterization of gene delivery vectors.

Overview

Authors: Jarryd M. Campbell1, Derek M. Korpela1, Hesong Han2,3, Sheng Zhao2,3, Dennis A. Webster1, Yen Anh H. Nguyen4, Nicholas Koes1, Robyn O. Aune1, Hinsoukpo Dagan1, Rebecca Milliken1, Jonathan K. Watts4,5, Niren Murthy2,3, Daniel F. Carlson1
ORCID iDs: Jarryd M. Campbell
  1. Recombinetics, New Brighton, MN 55112, USA
  2. Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA
  3. Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA
  4. RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA
  5. Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Medical School, Worcester, MA 01605, USA
Institutions: Recombinetics (United States) (United States); Innovative Genomics Institute (United States); University of California, Berkeley (United States); University of Massachusetts Chan Medical School (United States)
Journal: Molecular therapy. Advances, volume 34, issue 2, article 201729
Dates: received 8 April 2025; accepted 31 March 2026; published online 3 April 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.omta.2026.201729 · PMID 42137606 · PMCID PMC13148913 · OpenAlex W7148746065
Open access: hybrid, a free copy (OpenAlex)
Status: code on request
Categories: cellular / molecular (subfield)
Methods: Evoked potentials, Physiology & signal measures
Keywords: animal models, AAV vectors, non-viral gene delivery, CRISPR-Cas9, gene therapy, routes of administration, swine, biodistribution, reporter, mRNA delivery
Topic: Virus-based gene therapy research (Genetics, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Funding: Somatic Cell Genome Engineering Consortium; National Institutes of Health; Office Of The Director (U24OD026641)
Citations: not cited yet (Europe PMC); 55 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper says that its authors' code is available on request: it was not published with the paper, so there is nothing to verify.

The paper's code and data availability statement is in the Data section.

Tracing map

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Data

No dataset and no data link were found in the paper.

Code and data availability statement

The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the data are available on request
  • it says that the code is available on request

Read it in the paper: doi.org/10.1016/j.omta.2026.201729.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 2, 28 September 2026

  • Authors: added Jarryd M. Campbell (0009-0006-5591-2260); removed Jarryd M. Campbell

Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 13 authors, 10 keywords, 3 funders, 54 references.

Cite

This paper

Campbell, J. M., Korpela, D. M., Han, H., Zhao, S., Webster, D. A., Nguyen, Y. A. H., Koes, N., Aune, R. O., Dagan, H., Milliken, R., Watts, J. K., Murthy, N., & Carlson, D. F. (2026). Swine reporter model for preclinical evaluation and characterization of gene delivery vectors. Molecular therapy. Advances, 34(2), 201729. https://doi.org/10.1016/j.omta.2026.201729

BibTeX

@article{campbell2026swine,
author = {Campbell, Jarryd M. and Korpela, Derek M. and Han, Hesong and Zhao, Sheng and Webster, Dennis A. and Nguyen, Yen Anh H. and Koes, Nicholas and Aune, Robyn O. and Dagan, Hinsoukpo and Milliken, Rebecca and Watts, Jonathan K. and Murthy, Niren and Carlson, Daniel F.},
title = {{Swine reporter model for preclinical evaluation and characterization of gene delivery vectors}},
journal = {Molecular therapy. Advances},
year = {2026},
month = apr,
volume = {34},
number = {2},
pages = {201729},
publisher = {American Society of Gene \& Cell Therapy},
issn = {3117-387X},
doi = {10.1016/j.omta.2026.201729},
url = {https://doi.org/10.1016/j.omta.2026.201729},
pmid = {42137606},
pmcid = {PMC13148913}
}

RIS

TY - JOUR
AU - Campbell, Jarryd M.
AU - Korpela, Derek M.
AU - Han, Hesong
AU - Zhao, Sheng
AU - Webster, Dennis A.
AU - Nguyen, Yen Anh H.
AU - Koes, Nicholas
AU - Aune, Robyn O.
AU - Dagan, Hinsoukpo
AU - Milliken, Rebecca
AU - Watts, Jonathan K.
AU - Murthy, Niren
AU - Carlson, Daniel F.
TI - Swine reporter model for preclinical evaluation and characterization of gene delivery vectors
T2 - Molecular therapy. Advances
J2 - Mol Ther Adv
PY - 2026
DA - 2026/04/03
VL - 34
IS - 2
SP - 201729
SN - 3117-387X
PB - American Society of Gene & Cell Therapy
DO - 10.1016/j.omta.2026.201729
UR - https://doi.org/10.1016/j.omta.2026.201729
LA - en
ER -

CSL-JSON

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