OSCR

Boosting CAR T cell functionality with oncolytic viruses for the treatment of pediatric diffuse midline gliomas.

Overview

Authors: Konstantinos Vazaios1, Antonio C Tallon-Cobos1, Louisa PJ van Oosterhout1, Piotr Waranecki1, Annelisa M Cornel1,2, Noël MM Dautzenberg1,2, Marliek van Hoesel1, Caitlyn Forbes1, Stefan Nierkens1,2, Vera Kemp3, Rob C Hoeben3, Jasper van der Lugt1, Friso G Calkoen1, Esther Hulleman1
ORCID iDs: Konstantinos Vazaios, Louisa PJ van Oosterhout, Piotr Waranecki
  1. Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, the Netherlands
  2. Center for Translational Immunology, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands
  3. Department of Cell and Chemical Biology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, the Netherlands
Institutions: Princess Máxima Center (Netherlands); University Medical Center Utrecht (Netherlands); Leiden University Medical Center (Netherlands)
Journal: Molecular therapy. Oncology, volume 34, issue 2, article 201191
Dates: received 23 June 2025; accepted 26 March 2026; published online 30 March 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.omton.2026.201191 · PMID 42100144 · PMCID PMC13145386 · OpenAlex W7143988247
Open access: gold, a free copy (OpenAlex)
Status: code on request (how the code is found and verified)
Categories: other condition (population)
Methods: Statistics, Smoothing, state filtering, decompositions, Preprocessing
Keywords: MT: Special Issue - Advancements in pediatric cancer therapy, pediatric, diffuse midline glioma, oncolytic viral therapy, immune-oncology, immunotherapy, CAR T-cell therapy, Goravir, R124, B7H3, GD2
Topic: CAR-T cell therapy research (Oncology, Medicine), according to OpenAlex
Funding: Prinses Máxima Centrum Foundation
Citations: cited by 2 papers (Europe PMC); 62 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper says that its authors' code is available on request: it was not published with the paper, so there is nothing to verify.

The paper's code and data availability statement is in the Data section.

Tracing map

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Data

Datasets cited

Code and data availability statement

The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it points to a dataset: NCBI GEO GSE300244
  • it says that the data are available on request
  • it says that the code is available on request

Read it in the paper: doi.org/10.1016/j.omton.2026.201191.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 14 authors, 11 keywords, 1 funder, 61 references.

Cite

This paper

Vazaios, K., Tallon-Cobos, A. C., van Oosterhout, L. P., Waranecki, P., Cornel, A. M., Dautzenberg, N. M., van Hoesel, M., Forbes, C., Nierkens, S., Kemp, V., Hoeben, R. C., van der Lugt, J., Calkoen, F. G., & Hulleman, E. (2026). Boosting CAR T cell functionality with oncolytic viruses for the treatment of pediatric diffuse midline gliomas. Molecular therapy. Oncology, 34(2), 201191. https://doi.org/10.1016/j.omton.2026.201191

BibTeX

@article{vazaios2026boosting,
author = {Vazaios, Konstantinos and Tallon-Cobos, Antonio C and van Oosterhout, Louisa PJ and Waranecki, Piotr and Cornel, Annelisa M and Dautzenberg, Noël MM and van Hoesel, Marliek and Forbes, Caitlyn and Nierkens, Stefan and Kemp, Vera and Hoeben, Rob C and van der Lugt, Jasper and Calkoen, Friso G and Hulleman, Esther},
title = {{Boosting CAR T cell functionality with oncolytic viruses for the treatment of pediatric diffuse midline gliomas}},
journal = {Molecular therapy. Oncology},
year = {2026},
month = mar,
volume = {34},
number = {2},
pages = {201191},
publisher = {American Society of Gene \& Cell Therapy},
issn = {2950-3299},
doi = {10.1016/j.omton.2026.201191},
url = {https://doi.org/10.1016/j.omton.2026.201191},
pmid = {42100144},
pmcid = {PMC13145386}
}

RIS

TY - JOUR
AU - Vazaios, Konstantinos
AU - Tallon-Cobos, Antonio C
AU - van Oosterhout, Louisa PJ
AU - Waranecki, Piotr
AU - Cornel, Annelisa M
AU - Dautzenberg, Noël MM
AU - van Hoesel, Marliek
AU - Forbes, Caitlyn
AU - Nierkens, Stefan
AU - Kemp, Vera
AU - Hoeben, Rob C
AU - van der Lugt, Jasper
AU - Calkoen, Friso G
AU - Hulleman, Esther
TI - Boosting CAR T cell functionality with oncolytic viruses for the treatment of pediatric diffuse midline gliomas
T2 - Molecular therapy. Oncology
J2 - Mol Ther Oncol
PY - 2026
DA - 2026/03/30
VL - 34
IS - 2
SP - 201191
SN - 2950-3299
PB - American Society of Gene & Cell Therapy
DO - 10.1016/j.omton.2026.201191
UR - https://doi.org/10.1016/j.omton.2026.201191
LA - en
ER -

CSL-JSON

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