OSCR

USP11 drives stress-induced synaptic structural deficits and depression-like behaviors through GSK3β/mTOR signaling.

Overview

Authors: Ningyuan Li1, Yuqi Feng1, Qian Gong1, Hao Duan1, Hanchun Yan1, Honghan Zhang1, Chao Wang1, Zhongchun Liu1,2,3
  1. Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China
  2. Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China
  3. State Key Laboratory of Metabolism and Regulation in Complex Organisms, Wuhan University, Wuhan, China
Institutions: Renmin Hospital of Wuhan University (China); Wuhan University (China)
Journal: Neurobiology of stress, volume 42, article 100791
Dates: received 15 November 2025; accepted 2 March 2026; published online 9 March 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1016/j.ynstr.2026.100791 · PMID 41889422 · PMCID PMC13014669 · OpenAlex W7134262947
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: mouse (organism), depression (population), cellular / molecular (subfield)
Methods: Statistics, Spectral & time-frequency
Keywords: Depression, GSK3β, USP11, Synaptic remodeling, Chronic stress
Topic: Ubiquitin and proteasome pathways (Molecular Biology, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Funding: National Natural Science Foundation of China (U21A20364, 82501827)
Citations: not cited yet (Europe PMC); 46 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Data availability statement

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  • it says that the data are available on request

Read it in the paper: doi.org/10.1016/j.ynstr.2026.100791.

Versions

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Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, pages, dates, 8 authors, 5 keywords, 1 funder, 46 references.

Cite

This paper

Li, N., Feng, Y., Gong, Q., Duan, H., Yan, H., Zhang, H., Wang, C., & Liu, Z. (2026). USP11 drives stress-induced synaptic structural deficits and depression-like behaviors through GSK3β/mTOR signaling. Neurobiology of stress, 42, 100791. https://doi.org/10.1016/j.ynstr.2026.100791

BibTeX

@article{li2026usp11,
author = {Li, Ningyuan and Feng, Yuqi and Gong, Qian and Duan, Hao and Yan, Hanchun and Zhang, Honghan and Wang, Chao and Liu, Zhongchun},
title = {{USP11 drives stress-induced synaptic structural deficits and depression-like behaviors through GSK3β/mTOR signaling}},
journal = {Neurobiology of stress},
year = {2026},
month = mar,
volume = {42},
pages = {100791},
publisher = {Elsevier},
issn = {2352-2895},
doi = {10.1016/j.ynstr.2026.100791},
url = {https://doi.org/10.1016/j.ynstr.2026.100791},
pmid = {41889422},
pmcid = {PMC13014669}
}

RIS

TY - JOUR
AU - Li, Ningyuan
AU - Feng, Yuqi
AU - Gong, Qian
AU - Duan, Hao
AU - Yan, Hanchun
AU - Zhang, Honghan
AU - Wang, Chao
AU - Liu, Zhongchun
TI - USP11 drives stress-induced synaptic structural deficits and depression-like behaviors through GSK3β/mTOR signaling
T2 - Neurobiology of stress
J2 - Neurobiol Stress
PY - 2026
DA - 2026/03/09
VL - 42
SP - 100791
SN - 2352-2895
PB - Elsevier
DO - 10.1016/j.ynstr.2026.100791
UR - https://doi.org/10.1016/j.ynstr.2026.100791
LA - en
ER -

CSL-JSON

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"language": "en",
"issued": {
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