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Distinct manifestations of excitatory-inhibitory imbalance associated with amyloid-β and tau in patients with Alzheimer’s disease

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Paper

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The authors' code

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  1. # megabtaufdg

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Overview

Authors: Kamalini G Ranasinghe1, Kiwamu Kudo2, Faatimah Syed1, Claire Yballa1, Joel H Kramer1, Bruce L Miller1, Katherine P Rankin1, Paul A Garcia3, Heidi E Kirsch3, Keith Vossel1,4, William Jagust5, Gil D Rabinovici1,2, Srikantan S Nagarajan2
ORCID iDs: Kamalini G Ranasinghe, Kiwamu Kudo, Katherine P Rankin, Heidi E Kirsch, William Jagust, Gil D Rabinovici
  1. Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, CA USA
  2. Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA USA
  3. Epilepsy Center, Department of Neurology, University of California San Francisco, San Francisco, CA USA
  4. Mary S. Easton Center for Alzheimer’s Disease Research, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA USA
  5. Department of Neuroscience, UC Berkeley, Berkeley, CA USA
Institutions: University of California, San Francisco (United States); University of California, Los Angeles (United States); University of California, Berkeley (United States)
Journal: n/a, volume 16, issue 1, article 7957
Dates: received 17 March 2025; accepted 30 July 2025; published online 26 August 2025
Type: Research article · Language: English
License: none stated
Identifiers: DOI 10.1038/s41467-025-62798-4 · PMCID PMC12381375 · OpenAlex W4413684641
Open access: gold, a free copy (OpenAlex)
Status: empty repository
Categories: MEG (modality), human (organism), Alzheimer's / dementia (population), epilepsy (population)
Methods: Statistics, Preprocessing, Spectral & time-frequency, Physiology & signal measures
Keywords: Alzheimer's disease
MeSH: Alzheimer Disease*, Amyloid beta-Peptides*, tau Proteins*, Aged, Aged, 80 and over, Brain, Epilepsy, Female, Humans, Magnetoencephalography, Male, Middle Aged (* major topic)
Topic: Epilepsy research and treatment (Psychiatry and Mental health, Medicine), according to OpenAlex
Funding: Alzheimer's Association (AARG-21-849773); NIA NIH HHS (K08 AG058749, R21 AG077498, R01 AG062542, R01 AG034570, RF1 AG062196, K23 AG038357, P30 AG062422, R01 AG045611, R01 AG088398); Larry L. Hillblom Foundation (2019-A-013-SUP); Alzheimer’s Association (AARG-21-849773); NIDCD NIH HHS (R01 DC021711, R01 DC017091, P50 DC019900, R21 DC021557); NIMH NIH HHS (R24 MH120037); NINDS NIH HHS (R01 NS100440, RF1 NS100440)
Citations: cited by 6 papers (Europe PMC); 74 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (none stated) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Repository

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kamalinigr/megabtaufdg

License: none: the authors keep all their rights
State: the link answers, verified on 26 September 2026
Evidence: files inventoried
Commit: f2af4246768443c717c69b5538a2207e87b2ad86, 16 July 2025
Size: 2 files, 0 scripts
Software Heritage: not archived
Found in: “Code availability”
Holds: README
Not found: license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 26 September 2026: the link answers
  • 26 September 2026: the link answers
1 file
At the source: github.com/kamalinigr/megabtaufdg

Code availability statement

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Read it in the paper: doi.org/10.1038/s41467-025-62798-4.

Tracing map

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Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

Datasets cited

Data availability statement

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Read it in the paper: doi.org/10.1038/s41467-025-62798-4.

Versions

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Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 13 authors, 1 keyword, 12 MeSH terms, 7 funders, 72 references.

Cite

This paper

Ranasinghe, K. G., Kudo, K., Syed, F., Yballa, C., Kramer, J. H., Miller, B. L., Rankin, K. P., Garcia, P. A., Kirsch, H. E., Vossel, K., Jagust, W., Rabinovici, G. D., & Nagarajan, S. S. (2025). Distinct manifestations of excitatory-inhibitory imbalance associated with amyloid-β and tau in patients with Alzheimer’s disease. Nature Communications, 16(1), 7957. https://doi.org/10.1038/s41467-025-62798-4

BibTeX

@article{ranasinghe2025distinct,
author = {Ranasinghe, Kamalini G and Kudo, Kiwamu and Syed, Faatimah and Yballa, Claire and Kramer, Joel H and Miller, Bruce L and Rankin, Katherine P and Garcia, Paul A and Kirsch, Heidi E and Vossel, Keith and Jagust, William and Rabinovici, Gil D and Nagarajan, Srikantan S},
title = {{Distinct manifestations of excitatory-inhibitory imbalance associated with amyloid-β and tau in patients with Alzheimer’s disease}},
journal = {Nature Communications},
year = {2025},
volume = {16},
number = {1},
pages = {7957},
publisher = {Nature Publishing Group},
issn = {2041-1723},
doi = {10.1038/s41467-025-62798-4},
url = {https://doi.org/10.1038/s41467-025-62798-4},
pmcid = {PMC12381375}
}

RIS

TY - JOUR
AU - Ranasinghe, Kamalini G
AU - Kudo, Kiwamu
AU - Syed, Faatimah
AU - Yballa, Claire
AU - Kramer, Joel H
AU - Miller, Bruce L
AU - Rankin, Katherine P
AU - Garcia, Paul A
AU - Kirsch, Heidi E
AU - Vossel, Keith
AU - Jagust, William
AU - Rabinovici, Gil D
AU - Nagarajan, Srikantan S
TI - Distinct manifestations of excitatory-inhibitory imbalance associated with amyloid-β and tau in patients with Alzheimer’s disease
T2 - Nature Communications
J2 - Nat Commun
PY - 2025
DA - 2025
VL - 16
IS - 1
SP - 7957
SN - 2041-1723
PB - Nature Publishing Group
DO - 10.1038/s41467-025-62798-4
UR - https://doi.org/10.1038/s41467-025-62798-4
LA - en
ER -

CSL-JSON

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