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Enhanced reward coding and condition-independent dynamics in optogenetically identified corticostriatal neurons in monkeys.

Overview

Authors: Adi Hovav-Lixenberg1, Yirat Henshke1, Tirzah Kreisel1, Eran Lottem1, Mati Joshua1
ORCID iDs: Adi Hovav-Lixenberg, Yirat Henshke, Eran Lottem, Mati Joshua
  1. Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem,Jerusalem, 91904 Israel
Institutions: Hebrew University of Jerusalem (Israel)
Journal: Nature communications, volume 17, issue 1, article 4760
Dates: received 23 April 2025; accepted 9 March 2026; published online 3 April 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41467-026-71046-2 · PMID 41927562 · PMCID PMC13216256 · OpenAlex W7148337973
Open access: gold, a free copy (OpenAlex)
Status: code on request
Categories: non-human primate (organism), systems (subfield)
Methods: Statistics, Evoked potentials, Single-unit activity, calcium imaging, Physiology & signal measures
Keywords: Reward
MeSH: Basal Ganglia*, Dopaminergic Neurons*, Neurons*, Reward*, Animals, Macaca mulatta, Male, Optogenetics (* major topic)
Topic: Neural dynamics and brain function (Cognitive Neuroscience, Neuroscience), according to OpenAlex
Funding: EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) (755745)
Citations: not cited yet (Europe PMC); 55 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Code availability statement

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  • it says that the code is available on request

Read it in the paper: doi.org/10.1038/s41467-026-71046-2.

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Data

Datasets cited

Data availability statement

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  • it points to a dataset: Zenodo 18467078
  • it says that the data are available on request

Read it in the paper: doi.org/10.1038/s41467-026-71046-2.

Versions

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Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 5 authors, 1 keyword, 8 MeSH terms, 1 funder, 53 references.

Cite

This paper

Hovav-Lixenberg, A., Henshke, Y., Kreisel, T., Lottem, E., & Joshua, M. (2026). Enhanced reward coding and condition-independent dynamics in optogenetically identified corticostriatal neurons in monkeys. Nature communications, 17(1), 4760. https://doi.org/10.1038/s41467-026-71046-2

BibTeX

@article{hovavlixenberg2026enhanced,
author = {Hovav-Lixenberg, Adi and Henshke, Yirat and Kreisel, Tirzah and Lottem, Eran and Joshua, Mati},
title = {{Enhanced reward coding and condition-independent dynamics in optogenetically identified corticostriatal neurons in monkeys}},
journal = {Nature communications},
year = {2026},
month = apr,
volume = {17},
number = {1},
pages = {4760},
publisher = {Nature Publishing Group},
issn = {2041-1723},
doi = {10.1038/s41467-026-71046-2},
url = {https://doi.org/10.1038/s41467-026-71046-2},
pmid = {41927562},
pmcid = {PMC13216256}
}

RIS

TY - JOUR
AU - Hovav-Lixenberg, Adi
AU - Henshke, Yirat
AU - Kreisel, Tirzah
AU - Lottem, Eran
AU - Joshua, Mati
TI - Enhanced reward coding and condition-independent dynamics in optogenetically identified corticostriatal neurons in monkeys
T2 - Nature communications
J2 - Nat Commun
PY - 2026
DA - 2026/04/03
VL - 17
IS - 1
SP - 4760
SN - 2041-1723
PB - Nature Publishing Group
DO - 10.1038/s41467-026-71046-2
UR - https://doi.org/10.1038/s41467-026-71046-2
LA - en
ER -

CSL-JSON

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"language": "en",
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