OSCR

CB1 receptor signaling at the cingulate-striatal circuit is anxiogenic.

Overview

Authors: Thomas J. Kelly1, Xiaojie Liu1, Yao Huang1, Ying Hu1, Vladislav Friedman1, Cecilia J. Hillard1, Qing-song Liu1
ORCID iDs: Thomas J. Kelly, Xiaojie Liu, Yao Huang, Vladislav Friedman, Cecilia J. Hillard, Qing-song Liu
  1. Department of Pharmacology and Toxicology, Medical College of Wisconsin,Milwaukee, WI USA
Institutions: Medical College of Wisconsin (United States)
Journal: Nature communications, volume 17, issue 1, article 4975
Dates: received 27 January 2025; accepted 23 March 2026; published online 8 April 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41467-026-71574-x · PMID 41951611 · PMCID PMC13237297 · OpenAlex W7152006786
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: mouse (organism), other condition (population)
Methods: Statistics, Preprocessing, Single-unit activity, calcium imaging
Keywords: Neural circuits, Stress and resilience
MeSH: Anxiety*, Corpus Striatum*, Gyrus Cinguli*, Receptor, Cannabinoid, CB1*, Animals, Behavior, Animal, Dronabinol, Endocannabinoids, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Neurons, Signal Transduction (* major topic)
Topic: Cannabis and Cannabinoid Research (Pharmacology, Medicine), according to OpenAlex
Funding: National Institute of Mental Health (R01MH121454, R01MH140483); National Institute on Drug Abuse (R01DA035217)
Citations: not cited yet (Europe PMC); 70 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Data availability statement

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  • no repository, dataset or request procedure was recognized in it

Read it in the paper: doi.org/10.1038/s41467-026-71574-x.

Versions

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Version 1, 29 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 7 authors, 2 keywords, 14 MeSH terms, 2 funders, 69 references.

Cite

This paper

Kelly, T. J., Liu, X., Huang, Y., Hu, Y., Friedman, V., Hillard, C. J., & Liu, Q.-s. (2026). CB1 receptor signaling at the cingulate-striatal circuit is anxiogenic. Nature communications, 17(1), 4975. https://doi.org/10.1038/s41467-026-71574-x

BibTeX

@article{kelly2026cb1,
author = {Kelly, Thomas J. and Liu, Xiaojie and Huang, Yao and Hu, Ying and Friedman, Vladislav and Hillard, Cecilia J. and Liu, Qing-song},
title = {{CB1 receptor signaling at the cingulate-striatal circuit is anxiogenic}},
journal = {Nature communications},
year = {2026},
month = apr,
volume = {17},
number = {1},
pages = {4975},
publisher = {Nature Publishing Group},
issn = {2041-1723},
doi = {10.1038/s41467-026-71574-x},
url = {https://doi.org/10.1038/s41467-026-71574-x},
pmid = {41951611},
pmcid = {PMC13237297}
}

RIS

TY - JOUR
AU - Kelly, Thomas J.
AU - Liu, Xiaojie
AU - Huang, Yao
AU - Hu, Ying
AU - Friedman, Vladislav
AU - Hillard, Cecilia J.
AU - Liu, Qing-song
TI - CB1 receptor signaling at the cingulate-striatal circuit is anxiogenic
T2 - Nature communications
J2 - Nat Commun
PY - 2026
DA - 2026/04/08
VL - 17
IS - 1
SP - 4975
SN - 2041-1723
PB - Nature Publishing Group
DO - 10.1038/s41467-026-71574-x
UR - https://doi.org/10.1038/s41467-026-71574-x
LA - en
ER -

CSL-JSON

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"container-title": "Nature communications",
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"ISSN": "2041-1723",
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"language": "en",
"issued": {
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}

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