Multi-metric evaluations of acute psychedelic effects on fMRI brain entropy.
The 17 matches · 1 of them tie a paragraph to a whole file, not to given lines: a weak match, whose lines are not tinted
- [1] § Methods › Entropy of dynamic connectivity › LEiDA-state Markov-rate ↔ copbet_py/functions/CopBET_LEiDA_transition_entropy.py, lines 1–33 · score 0.88 · phase coherence matrices, instantaneous phases, Hilbert transform, Leading Eigenvector, LEiDA, transition
- [2] § Methods › Entropy of dynamic connectivity › Integration/Segregation-state distribution ↔ copbet_py/functions/CopBET_temporal_entropy.py, lines 1–34 · score 0.84 · cartographic profile, sliding window, module degree, participation coefficient, Louvain, score
- [3] § Methods › Entropy of dynamic connectivity › Motif-connectivity distribution ↔ copbet_py/functions/CopBET_motif_connectivity_entropy.py, lines 1–44 · score 0.83 · overlapping sliding window, possible graph, partial correlation, window lengths, Shannon entropy, Motif
- [4] § Methods › Entropy of dynamic connectivity › Dynamic conditional correlation distribution ↔ CopBET_main_CH2016data.m, lines 128–160 · score 0.82 · medial frontal, subcortical cerebellar, ROI DCC, Shen, motor, edges
- [5] § Methods › Entropy of dynamic connectivity › Integration/Segregation-state distribution ↔ functions/CopBET_temporal_entropy.m, lines 87–181 · score 0.76 · cartographic profile, module degree, sliding, Louvain, modularity, dimensional
- [6] § Results › Motif-connectivity distribution entropy ↔ copbet_py/functions/CopBET_motif_connectivity_entropy.py, lines 52–107 · score 0.76 · 15–150 s, motif connectivity, window length, 15 s, ROI
- [7] § Methods › Entropy of dynamic connectivity › Meta-state complexity ↔ copbet_py/functions/CopBET_metastate_series_complexity.py, lines 1–37 · score 0.71 · LZ76 exhaustive, Lempel Ziv complexity, correlation distance, binary, sequence, clustered
- [8] § Methods › Entropy of dynamic connectivity › Meta-state complexity ↔ copbet_py/functions/helper_functions/lempel_ziv.py, lines 13–134 · score 0.70 · LZ76 exhaustive, Lempel Ziv complexity, binary sequence
- [9] § Methods › Entropy of regional dynamics › BOLD complexity ↔ copbet_py/functions/CopBET_time_series_complexity.py, lines 1–37 · score 0.67 · Hilbert transformed, Lempel Ziv complexity, amplitude, LZ78, space, temporal
- [10] § Methods › Entropy of static connectivity › Normalised Global Spatial Complexity ↔ copbet_py/functions/CopBET_von_Neumann_entropy.py, lines 31–69 · score 0.66 · Von Neumann entropy, zero eigenvalues, log, mask, sum, matrix
- [11] § Methods › Entropy of static connectivity › Von Neumann entropy ↔ copbet_py/functions/CopBET_von_Neumann_entropy.py, lines 31–69 · score 0.60 · von Neumann entropy, correlation matrix, log, eigenvalues
- [12] § Methods › Entropy of static connectivity › Out-network connectivity distribution entropy ↔ copbet_py/functions/CopBET_diversity_coefficient.py, lines 1–31 · score 0.60 · diversity coefficient, network Connectivity, modularity, ROI, matrix, Brain
- [13] § Methods › Entropy of static connectivity › Out-network connectivity distribution entropy ↔ functions/CopBET_diversity_coefficient.m, lines 49–87 · score 0.60 · diversity coefficient, connectivity matrix, Louvain, modularity, algorithm, scan
- [14] § Methods › Statistical model ↔ statistics/permlme.R, the whole file · a weak match · score 0.57 · nlme, Wald, model, covariates, residuals, regressed
- [15] § Methods › Correlation between metrics ↔ copbet_py/functions/CopBET_motif_connectivity_entropy.py, lines 1–44 · score 0.52 · motif connectivity, Pearson correlation, brain entropy, graph, windows
- [16] § Methods › Entropy of static connectivity › Degree distribution entropy ↔ copbet_py/functions/CopBET_degree_distribution_entropy.py, lines 34–73 · score 0.52 · Pearson correlation, distribution entropy, Shannon entropy, absolute, zero, thresholded
- [17] § Results › Von Neumann entropy ↔ copbet_py/functions/CopBET_von_Neumann_entropy.py, lines 1–28 · score 0.51 · Von Neumann entropy, correlation matrices, rho, Pearson
Paper
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The authors' code
Python · 231 lines · 7.1 KB · no license · 3 matches
- """
- CopBET_motif_connectivity_entropy
- ===================================
- Copenhagen Brain Entropy Toolbox: Motif-connectivity entropy.
- Evaluates motif-connectivity entropy as in Tagliazucchi et al., 2014.
- Non-overlapping sliding windows of varying lengths are slid across the
- data. In each window, the partial correlation between the 4 ROIs
- (conditioned on the remaining ROIs and a motion confound) is binarized
- by p-value. The resulting 6-bit connectivity pattern is matched to one
- of 64 possible graphs. Shannon entropy of the graph distribution is
- returned per window length. The mean across window lengths is also returned.
- NOTE: This function requires exactly 4 ROIs. If more are provided, the
- first 4 are used unless roi_indices is specified.
- Input
- -----
- sessions : list of np.ndarray, each shape (T, N) with N >= 4
- ROI mean time series per session (demeaned, standardized recommended).
- motion : list of np.ndarray or None
- Motion confound time series, each shape (T, n_confounds).
- If None, partial correlations are replaced by Pearson correlations.
- TR : float
- Repetition time in seconds (default 2.0).
- roi_indices : list of int or None
- Indices of the 4 ROIs to use. Default: [0, 1, 2, 3].
- Returns
- -------
- entropy : list of dict with keys:
- 'per_window_length' : np.ndarray, shape (n_wl,) — entropy per window length
- 'mean' : float — mean entropy across window lengths
- Reference
- ---------
- Tagliazucchi et al., 2014.
- Please cite McCulloch, Olsen et al., 2023 if you use CopBET.
- """
- import numpy as np
- from scipy import stats
- from itertools import product
- # All 64 possible binary graphs on 6 edges
- _POSSIBLE_GRAPHS = np.array(list(product([0, 1], repeat=6)), dtype=float).T # (6, 64)
- _ROI_PAIRS = [(0, 1), (0, 2), (0, 3), (1, 2), (1, 3), (2, 3)]
- def CopBET_motif_connectivity_entropy(sessions, motion=None, TR=2.0,
- roi_indices=None,
- window_lengths_sec=None):
- """
- Compute motif-connectivity Shannon entropy.
- Parameters
- ----------
- sessions : list of np.ndarray, each shape (T, N), N >= 4
- motion : list of np.ndarray or None
- Motion confound series per session, shape (T, n_confounds).
- TR : float
- roi_indices : list of int or None
- Indices for the 4 ROIs. Default [0, 1, 2, 3].
- window_lengths_sec : array-like or None
- Window lengths in seconds. Default: 15 to 150 seconds step 1.
- Returns
- -------
- entropy : list of dict
- """
- if roi_indices is None:
- roi_indices = [0, 1, 2, 3]
- if window_lengths_sec is None:
- window_lengths_sec = np.arange(15, 151)
- if motion is None:
- motion = [None] * len(sessions)
- entropy = []
- for ses, ts in enumerate(sessions):
- ts = np.asarray(ts, dtype=float)
- # Extract 4 ROIs, demean, standardize
- data4 = ts[:, roi_indices] # (T, 4)
- data4 = (data4 - data4.mean(axis=0)) / (data4.std(axis=0) + 1e-10)
- data4 = data4.T # (4, T)
- rp = motion[ses]
- if rp is not None:
- rp = np.asarray(rp, dtype=float)
- rp = _fwd_calc(rp)[:, np.newaxis] # (T, 1)
- else:
- rp = np.zeros((ts.shape[0], 1))
- word_counts = _state_distribution(data4, rp, TR, window_lengths_sec)
- ent = _shannon_entropy(word_counts)
- entropy.append({
- 'per_window_length': ent,
- 'mean': float(np.nanmean(ent)),
- 'window_lengths_sec': window_lengths_sec,
- })
- return entropy
- def _fwd_calc(rp):
- """
- Compute framewise displacement from 6 motion parameters (3 trans, 3 rot).
- Rotation parameters are converted from radians to mm (r=50 mm).
- """
- radius = 50.0
- ts = rp.copy()
- ts[:, 3:6] = (2 * radius * np.pi / 360) * ts[:, 3:6] * (180 / np.pi)
- dts = np.diff(ts, axis=0)
- fwd = np.concatenate([[0], np.sum(np.abs(dts), axis=1)])
- fwd = (fwd - fwd.mean()) / (fwd.std() + 1e-10)
- return fwd
- def _state_distribution(data, rp, TR, window_lengths_sec):
- """
- For each window length, count occurrences of each 64-bit graph pattern.
- Parameters
- ----------
- data : np.ndarray, shape (4, T)
- rp : np.ndarray, shape (T, n_confounds)
- TR : float
- window_lengths_sec : array-like
- Returns
- -------
- word_counts : np.ndarray, shape (n_wl, 64)
- """
- T = data.shape[1]
- eff_wl = np.round(np.asarray(window_lengths_sec) / TR).astype(int)
- eff_wl = np.maximum(eff_wl, 5) # minimum window of 5 TRs
- word_counts = np.zeros((len(window_lengths_sec), 64), dtype=int)
- for wl_idx, wl in enumerate(eff_wl):
- if wl_idx > 0 and eff_wl[wl_idx] == eff_wl[wl_idx - 1]:
- word_counts[wl_idx] = word_counts[wl_idx - 1]
- continue
- # Non-overlapping windows
- window_starts = np.arange(0, T - wl + 1, wl)
- for ws in window_starts:
- data_win = data[:, ws:ws + wl] # (4, wl)
- rp_win = np.abs(rp[ws:ws + wl]) # (wl, n_confounds)
- graph_bits = np.zeros(6, dtype=int)
- for pair_idx, (i, j) in enumerate(_ROI_PAIRS):
- # Confound: all other ROIs + motion
- other_rois = [k for k in range(4) if k != i and k != j]
- confounds = np.hstack([
- data_win[other_rois, :].T, # (wl, 2)
- rp_win # (wl, n_confounds)
- ]) # (wl, n_confounds+2)
- xi = data_win[i, :]
- xj = data_win[j, :]
- try:
- r, p = _partial_corr(xi, xj, confounds)
- graph_bits[pair_idx] = int(p < 0.05 / 6) # Bonferroni
- except Exception:
- graph_bits[pair_idx] = 0
- # Find matching graph pattern
- diff = np.sum(np.abs(_POSSIBLE_GRAPHS - graph_bits[:, np.newaxis]), axis=0)
- word_idx = np.argmin(diff)
- word_counts[wl_idx, word_idx] += 1
- return word_counts
- def _partial_corr(x, y, z):
- """
- Compute partial correlation of x and y controlling for z.
- Parameters
- ----------
- x, y : np.ndarray, shape (T,)
- z : np.ndarray, shape (T, k)
- Returns
- -------
- r : float, p : float
- """
- T = len(x)
- if z.shape[1] == 0:
- return stats.pearsonr(x, y)
- # Residualize x and y on z
- z_with_intercept = np.column_stack([np.ones(T), z])
- px = np.linalg.lstsq(z_with_intercept, x, rcond=None)[0]
- py = np.linalg.lstsq(z_with_intercept, y, rcond=None)[0]
- res_x = x - z_with_intercept @ px
- res_y = y - z_with_intercept @ py
- return stats.pearsonr(res_x, res_y)
- def _shannon_entropy(word_counts):
- """
- Compute Shannon entropy of graph distribution for each window length.
- Parameters
- ----------
- word_counts : np.ndarray, shape (n_wl, 64)
- Returns
- -------
- ent : np.ndarray, shape (n_wl,)
- """
- ent = np.zeros(word_counts.shape[0])
- for wl in range(word_counts.shape[0]):
- total = word_counts[wl].sum()
- if total == 0:
- ent[wl] = np.nan
- continue
- prob = word_counts[wl] / total
- mask = prob > 0
- ent[wl] = np.sum(prob[mask] * np.log2(1.0 / prob[mask]))
- return ent
CopBET_motif_connectivity_entropy.py at commit eb4e455, no license · at the source
Overview
- Neurobiology Research Unit, Copenhagen University Hospital, Rigshospitalet,Copenhagen, Denmark
- Faculty of Health and Medical Sciences, University of Copenhagen,Copenhagen, Denmark
- Department of Applied Mathematics and Computer Science, Technical University of Denmark,Kgs. Lyngby, Denmark
- Section of Biostatistics, Department of Public Health, University of Copenhagen,Copenhagen, Denmark
- Department of Psychology, University of Copenhagen,Copenhagen, Denmark
- Department of Psychiatry Odense-Svendborg, University Hospital of Southern Denmark,Svendborg, Denmark
- Department of Clinical Medicine, University of Copenhagen,Copenhagen, Denmark
- Department of Drug Design and Pharmacology, University of Copenhagen,Copenhagen, Denmark
Abstract
A prominent theory of psychedelics is that they increase brain entropy. Thirteen studies have evaluated psychedelic effects on fMRI brain entropy, each applying a distinct measure. Here we evaluated these metrics in an independent 28-participant healthy cohort with 121 pre- and post-psilocybin fMRI scans. We assessed relations between brain entropy and objective and subjective psychedelic drug effects using linear mixed-effects models. All metrics were evaluated using two parcellation strategies and 7 denoising pipelines. We observed consistent significant positive associations for Shannon entropy of the spatial eigendistribution of the time by voxel matrix, path-length, instantaneous correlations, brain-state switching, and sample entropy at short time-scales. We consistently did not observe significant effects for 8 of 14 entropy metrics and observe inconsistent positive effects for Lempel-Ziv complexity of the BOLD signal. Brain entropy quantifications showed limited inter-measure correlations. Our observations support a nuanced acute psychedelic effect on brain entropy, empirically demonstrating that these metrics do not reflect a singular construct.
Reproduced under the paper's license (CC BY), from the paper cited above.
Repositories
Its files are read in the Code ↔ Paper reader above, with 17 matches between paragraphs and lines of code.
anders-s-olsen/CopBET
eb4e4559bd9cdcc7b70bfd6c8b6a428044e98380, 13 August 2026Availability: 1 check, the latest on 27 September 2026: the link answers
- 27 September 2026: the link answers
454 files
- CopBET_CarhartHarris_201
6_data.m , MATLAB, 105 lines - CopBET_main_CH2016data.m
, MATLAB, 303 lines, 1 match - LSDdata/
LSDdata_ROI.m , MATLAB, 94 lines - copbet_py/
example_script.py , Python, 99 lines - copbet_py/
functions/ , Python, 87 linesCopBET_DCC_entropy.py - copbet_py/
functions/ , Python, 175 lines, 1 matchCopBET_LEiDA_transition_ entropy.py - copbet_py/
functions/ , Python, 130 linesCopBET_NGSC.py - copbet_py/
functions/ , Python, 137 lines, 1 matchCopBET_degree_distributi on_entropy.py - copbet_py/
functions/ , Python, 95 lines, 1 matchCopBET_diversity_coeffic ient.py - copbet_py/
functions/ , Python, 120 linesCopBET_geodesic_entropy. py - copbet_py/
functions/ , Python, 94 linesCopBET_intranetwork_sync hrony.py - copbet_py/
functions/ , Python, 162 lines, 1 matchCopBET_metastate_series_ complexity.py - copbet_py/
functions/ , Python, 231 lines, 3 matchesCopBET_motif_connectivit y_entropy.py - copbet_py/
functions/ , Python, 71 linesCopBET_sample_entropy.py - copbet_py/
functions/ , Python, 182 lines, 1 matchCopBET_temporal_entropy. py - copbet_py/
functions/ , Python, 114 lines, 1 matchCopBET_time_series_compl exity.py - copbet_py/
functions/ , Python, 69 lines, 3 matchesCopBET_von_Neumann_entro py.py - copbet_py/
functions/ , Python, 13 lines__init__.py - copbet_py/
functions/ , Python, 2 lineshelper_functions/ __init__.py - copbet_py/
functions/ , Python, 170 lines, 1 matchhelper_functions/ lempel_ziv.py - copbet_py/
functions/ , Python, 119 lineshelper_functions/ sample_entropy_core.py - copbet_py/
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BCT/ , MATLAB, 45 lines2013_12_25 BCT/ transitivity_wd.m - external/
BCT/ , MATLAB, 21 lines2013_12_25 BCT/ transitivity_wu.m - external/
BCT/ , MATLAB, 49 lines2013_12_25 BCT/ weight_conversion.m - external/
BCT/ , MATLAB, 41 lines2013_12_25 BCT/ writetoPAJ.m - external/
BCT/ , MATLAB, 53 lines2019_03_03_BCT/ adjacency_plot_und.m - external/
BCT/ , MATLAB, 60 lines2019_03_03_BCT/ agreement.m - external/
BCT/ , MATLAB, 28 lines2019_03_03_BCT/ agreement_weighted.m - external/
BCT/ , MATLAB, 135 lines2019_03_03_BCT/ align_matrices.m - external/
BCT/ , MATLAB, 64 lines2019_03_03_BCT/ assortativity_bin.m - external/
BCT/ , MATLAB, 62 lines2019_03_03_BCT/ assortativity_wei.m - external/
BCT/ , MATLAB, 64 lines2019_03_03_BCT/ backbone_wu.m - external/
BCT/ , MATLAB, 53 lines2019_03_03_BCT/ betweenness_bin.m - external/
BCT/ , MATLAB, 76 lines2019_03_03_BCT/ betweenness_wei.m - external/
BCT/ , MATLAB, 62 lines2019_03_03_BCT/ breadth.m - external/
BCT/ , MATLAB, 39 lines2019_03_03_BCT/ breadthdist.m - external/
BCT/ , MATLAB, 79 lines2019_03_03_BCT/ charpath.m - external/
BCT/ , MATLAB, 102 lines2019_03_03_BCT/ clique_communities.m - external/
BCT/ , MATLAB, 35 lines2019_03_03_BCT/ clustering_coef_bd.m - external/
BCT/ , MATLAB, 28 lines2019_03_03_BCT/ clustering_coef_bu.m - external/
BCT/ , MATLAB, 42 lines2019_03_03_BCT/ clustering_coef_wd.m - external/
BCT/ , MATLAB, 30 lines2019_03_03_BCT/ clustering_coef_wu.m - external/
BCT/ , MATLAB, 136 lines2019_03_03_BCT/ clustering_coef_wu_sign. m - external/
BCT/ , MATLAB, 198 lines2019_03_03_BCT/ community_louvain.m - external/
BCT/ , MATLAB, 96 lines2019_03_03_BCT/ consensus_und.m - external/
BCT/ , MATLAB, 88 lines2019_03_03_BCT/ core_periphery_dir.m - external/
BCT/ , MATLAB, 45 lines2019_03_03_BCT/ cycprob.m - external/
BCT/ , MATLAB, 116 lines2019_03_03_BCT/ data_and_demos/ demo_efficiency_measures .m - external/
BCT/ , MATLAB, 52 lines2019_03_03_BCT/ data_and_demos/ demo_generative_models_g eometric.m - external/
BCT/ , MATLAB, 52 lines2019_03_03_BCT/ data_and_demos/ demo_generative_models_n eighbors.m - external/
BCT/ , MATLAB, 31 lines2019_03_03_BCT/ degrees_dir.m - external/
BCT/ , MATLAB, 22 lines2019_03_03_BCT/ degrees_und.m - external/
BCT/ , MATLAB, 24 lines2019_03_03_BCT/ density_dir.m - external/
BCT/ , MATLAB, 28 lines2019_03_03_BCT/ density_und.m - external/
BCT/ , MATLAB, 33 lines2019_03_03_BCT/ diffusion_efficiency.m - external/
BCT/ , MATLAB, 45 lines2019_03_03_BCT/ distance_bin.m - external/
BCT/ , MATLAB, 71 lines2019_03_03_BCT/ distance_wei.m - external/
BCT/ , MATLAB, 121 lines2019_03_03_BCT/ distance_wei_floyd.m - external/
BCT/ , MATLAB, 46 lines2019_03_03_BCT/ diversity_coef_sign.m - external/
BCT/ , MATLAB, 68 lines2019_03_03_BCT/ edge_betweenness_bin.m - external/
BCT/ , MATLAB, 82 lines2019_03_03_BCT/ edge_betweenness_wei.m - external/
BCT/ , MATLAB, 48 lines2019_03_03_BCT/ edge_nei_overlap_bd.m - external/
BCT/ , MATLAB, 45 lines2019_03_03_BCT/ edge_nei_overlap_bu.m - external/
BCT/ , MATLAB, 76 lines2019_03_03_BCT/ efficiency_bin.m - external/
BCT/ , MATLAB, 136 lines2019_03_03_BCT/ efficiency_wei.m - external/
BCT/ , MATLAB, 37 lines2019_03_03_BCT/ eigenvector_centrality_u nd.m - external/
BCT/ , MATLAB, 45 lines2019_03_03_BCT/ erange.m - external/
BCT/ , MATLAB, 100 lines2019_03_03_BCT/ evaluate_generative_mode l.m - external/
BCT/ , MATLAB, 50 lines2019_03_03_BCT/ find_motif34.m - external/
BCT/ , MATLAB, 158 lines2019_03_03_BCT/ findpaths.m - external/
BCT/ , MATLAB, 41 lines2019_03_03_BCT/ findwalks.m - external/
BCT/ , MATLAB, 51 lines2019_03_03_BCT/ flow_coef_bd.m - external/
BCT/ , MATLAB, 83 lines2019_03_03_BCT/ gateway_coef_sign.m - external/
BCT/ , MATLAB, 241 lines2019_03_03_BCT/ generate_fc.m - external/
BCT/ , MATLAB, 897 lines2019_03_03_BCT/ generative_model.m - external/
BCT/ , MATLAB, 57 lines2019_03_03_BCT/ get_components.m - external/
BCT/ , MATLAB, 46 lines2019_03_03_BCT/ grid_communities.m - external/
BCT/ , MATLAB, 81 lines2019_03_03_BCT/ gtom.m - external/
BCT/ , MATLAB, 48 lines2019_03_03_BCT/ jdegree.m - external/
BCT/ , MATLAB, 59 lines2019_03_03_BCT/ kcore_bd.m - external/
BCT/ , MATLAB, 58 lines2019_03_03_BCT/ kcore_bu.m - external/
BCT/ , MATLAB, 27 lines2019_03_03_BCT/ kcoreness_centrality_bd. m - external/
BCT/ , MATLAB, 34 lines2019_03_03_BCT/ kcoreness_centrality_bu. m - external/
BCT/ , MATLAB, 91 lines2019_03_03_BCT/ latmio_dir.m - external/
BCT/ , MATLAB, 119 lines2019_03_03_BCT/ latmio_dir_connected.m - external/
BCT/ , MATLAB, 109 lines2019_03_03_BCT/ latmio_und.m - external/
BCT/ , MATLAB, 136 lines2019_03_03_BCT/ latmio_und_connected.m - external/
BCT/ , MATLAB, 150 lines2019_03_03_BCT/ link_communities.m - external/
BCT/ , MATLAB, 44 lines2019_03_03_BCT/ local_assortativity_wu_s ign.m - external/
BCT/ , MATLAB, 90 lines2019_03_03_BCT/ make_motif34lib.m - external/
BCT/ , MATLAB, 75 lines2019_03_03_BCT/ makeevenCIJ.m - external/
BCT/ , MATLAB, 49 lines2019_03_03_BCT/ makefractalCIJ.m - external/
BCT/ , MATLAB, 45 lines2019_03_03_BCT/ makelatticeCIJ.m - external/
BCT/ , MATLAB, 24 lines2019_03_03_BCT/ makerandCIJ_dir.m - external/
BCT/ , MATLAB, 25 lines2019_03_03_BCT/ makerandCIJ_und.m - external/
BCT/ , MATLAB, 81 lines2019_03_03_BCT/ makerandCIJdegreesfixed. m - external/
BCT/ , MATLAB, 47 lines2019_03_03_BCT/ makeringlatticeCIJ.m - external/
BCT/ , MATLAB, 29 lines2019_03_03_BCT/ maketoeplitzCIJ.m - external/
BCT/ , MATLAB, 80 lines2019_03_03_BCT/ matching_ind.m - external/
BCT/ , MATLAB, 39 lines2019_03_03_BCT/ matching_ind_und.m - external/
BCT/ , MATLAB, 45 lines2019_03_03_BCT/ mean_first_passage_time. m - external/
BCT/ , MATLAB, 284 lines2019_03_03_BCT/ mleme_constraint_model.m - external/
BCT/ , MATLAB, 124 lines2019_03_03_BCT/ modularity_dir.m - external/
BCT/ , MATLAB, 122 lines2019_03_03_BCT/ modularity_und.m - external/
BCT/ , MATLAB, 41 lines2019_03_03_BCT/ module_degree_zscore.m - external/
BCT/ , MATLAB, 78 lines2019_03_03_BCT/ motif3funct_bin.m - external/
BCT/ , MATLAB, 101 lines2019_03_03_BCT/ motif3funct_wei.m - external/
BCT/ , MATLAB, 56 lines2019_03_03_BCT/ motif3struct_bin.m - external/
BCT/ , MATLAB, 80 lines2019_03_03_BCT/ motif3struct_wei.m - external/
BCT/ , MATLAB, 88 lines2019_03_03_BCT/ motif4funct_bin.m - external/
BCT/ , MATLAB, 111 lines2019_03_03_BCT/ motif4funct_wei.m - external/
BCT/ , MATLAB, 65 lines2019_03_03_BCT/ motif4struct_bin.m - external/
BCT/ , MATLAB, 91 lines2019_03_03_BCT/ motif4struct_wei.m - external/
BCT/ , MATLAB, 112 lines2019_03_03_BCT/ navigation_wu.m - external/
BCT/ , MATLAB, 188 lines2019_03_03_BCT/ null_model_dir_sign.m - external/
BCT/ , MATLAB, 181 lines2019_03_03_BCT/ null_model_und_sign.m - external/
BCT/ , MATLAB, 57 lines2019_03_03_BCT/ pagerank_centrality.m - external/
BCT/ , MATLAB, 49 lines2019_03_03_BCT/ participation_coef.m - external/
BCT/ , MATLAB, 47 lines2019_03_03_BCT/ participation_coef_sign. m - external/
BCT/ , MATLAB, 97 lines2019_03_03_BCT/ partition_distance.m - external/
BCT/ , MATLAB, 84 lines2019_03_03_BCT/ path_transitivity.m - external/
BCT/ , MATLAB, 228 lines2019_03_03_BCT/ predict_fc.m - external/
BCT/ , MATLAB, 110 lines2019_03_03_BCT/ quasi_idempotence.m - external/
BCT/ , MATLAB, 70 lines2019_03_03_BCT/ randmio_dir.m - external/
BCT/ , MATLAB, 98 lines2019_03_03_BCT/ randmio_dir_connected.m - external/
BCT/ , MATLAB, 80 lines2019_03_03_BCT/ randmio_dir_signed.m - external/
BCT/ , MATLAB, 80 lines2019_03_03_BCT/ randmio_und.m - external/
BCT/ , MATLAB, 107 lines2019_03_03_BCT/ randmio_und_connected.m - external/
BCT/ , MATLAB, 80 lines2019_03_03_BCT/ randmio_und_signed.m - external/
BCT/ , MATLAB, 53 lines2019_03_03_BCT/ randomize_graph_partial_ und.m - external/
BCT/ , MATLAB, 140 lines2019_03_03_BCT/ randomizer_bin_und.m - external/
BCT/ , MATLAB, 68 lines2019_03_03_BCT/ reachdist.m - external/
BCT/ , MATLAB, 197 lines2019_03_03_BCT/ rentian_scaling_2d.m - external/
BCT/ , MATLAB, 209 lines2019_03_03_BCT/ rentian_scaling_3d.m - external/
BCT/ , MATLAB, 64 lines2019_03_03_BCT/ reorderMAT.m - external/
BCT/ , MATLAB, 105 lines2019_03_03_BCT/ reorder_matrix.m - external/
BCT/ , MATLAB, 107 lines2019_03_03_BCT/ reorder_mod.m - external/
BCT/ , MATLAB, 140 lines2019_03_03_BCT/ resource_efficiency_bin. m - external/
BCT/ , MATLAB, 37 lines2019_03_03_BCT/ retrieve_shortest_path.m - external/
BCT/ , MATLAB, 53 lines2019_03_03_BCT/ rich_club_bd.m - external/
BCT/ , MATLAB, 49 lines2019_03_03_BCT/ rich_club_bu.m - external/
BCT/ , MATLAB, 75 lines2019_03_03_BCT/ rich_club_wd.m - external/
BCT/ , MATLAB, 72 lines2019_03_03_BCT/ rich_club_wu.m - external/
BCT/ , MATLAB, 87 lines2019_03_03_BCT/ rout_efficiency.m - external/
BCT/ , MATLAB, 40 lines2019_03_03_BCT/ score_wu.m - external/
BCT/ , MATLAB, 117 lines2019_03_03_BCT/ search_information.m - external/
BCT/ , MATLAB, 27 lines2019_03_03_BCT/ strengths_dir.m - external/
BCT/ , MATLAB, 18 lines2019_03_03_BCT/ strengths_und.m - external/
BCT/ , MATLAB, 30 lines2019_03_03_BCT/ strengths_und_sign.m - external/
BCT/ , MATLAB, 24 lines2019_03_03_BCT/ subgraph_centrality.m - external/
BCT/ , MATLAB, 19 lines2019_03_03_BCT/ threshold_absolute.m - external/
BCT/ , MATLAB, 45 lines2019_03_03_BCT/ threshold_proportional.m - external/
BCT/ , MATLAB, 41 lines2019_03_03_BCT/ transitivity_bd.m - external/
BCT/ , MATLAB, 20 lines2019_03_03_BCT/ transitivity_bu.m - external/
BCT/ , MATLAB, 47 lines2019_03_03_BCT/ transitivity_wd.m - external/
BCT/ , MATLAB, 29 lines2019_03_03_BCT/ transitivity_wu.m - external/
BCT/ , MATLAB, 88 lines2019_03_03_BCT/ weight_conversion.m - external/
BCT/ , MATLAB, 41 lines2019_03_03_BCT/ writetoPAJ.m - external/
BCT/ , MATLAB, 137 linesrelease_notes.m - external/
Complexity Toolbox (LOFT)/ , MATLAB, not shown here__MACOSX/ complexity_GUI/ ._calcCrossApEn_noFilt.m - external/
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Complexity Toolbox (LOFT)/ , MATLAB, not shown here__MACOSX/ complexity_GUI/ ._complexity_MSE.m - external/
Complexity Toolbox (LOFT)/ , MATLAB, not shown here__MACOSX/ complexity_GUI/ ._complexity_cApEn.m - external/
Complexity Toolbox (LOFT)/ , MATLAB, not shown here__MACOSX/ complexity_GUI/ ._complexity_sampEn.m - external/
Complexity Toolbox (LOFT)/ , MATLAB, not shown here__MACOSX/ complexity_GUI/ ._displayImage.m - external/
Complexity Toolbox (LOFT)/ , MATLAB, not shown here__MACOSX/ complexity_GUI/ ._sample_entropy.m - external/
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Complexity Toolbox (LOFT)/ , MATLAB, 284 linescomplexity_GUI/ complexity_sampEn.m - external/
Complexity Toolbox (LOFT)/ , MATLAB, 95 linescomplexity_GUI/ cross_approx_entropy.m - external/
Complexity Toolbox (LOFT)/ , MATLAB, 197 linescomplexity_GUI/ dispTimeSeries.m - external/
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Complexity Toolbox (LOFT)/ , MATLAB, 268 linescomplexity_GUI/ preProcessing.m - external/
Complexity Toolbox (LOFT)/ , MATLAB, 38 linescomplexity_GUI/ readImages4D.m - external/
Complexity Toolbox (LOFT)/ , MATLAB, 57 linescomplexity_GUI/ sample_entropy.m - external/
Complexity Toolbox (LOFT)/ , MATLAB, 10 linescomplexity_GUI/ setbgcolor.m - external/
Complexity Toolbox (LOFT)/ , MATLAB, 146 linescomplexity_GUI/ verifyImgOri.m - external/
DCC_toolbox/ , MATLAB, 103 linesDCC2/ F.m - external/
DCC_toolbox/ , MATLAB, 103 linesDCC2/ G.m - external/
DCC_toolbox/ , MATLAB, 46 linesDCC2/ GarchDCC_X_example_2.m - external/
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DCC_toolbox/ , JavaScript, 888 linesDCC2/ codegen/ mex/ F/ html/ resources/ jQuery/ jquery.tablesorter.mod.j s - external/
DCC_toolbox/ , JavaScript, 488 linesDCC2/ codegen/ mex/ F/ html/ resources/ js/ coder_app.js - external/
DCC_toolbox/ , JavaScript, 150 linesDCC2/ codegen/ mex/ F/ html/ resources/ rtwannotate.js - external/
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DCC_toolbox/ , JavaScript, 888 linesDCC2/ codegen/ mex/ G/ html/ resources/ jQuery/ jquery.tablesorter.mod.j s - external/
DCC_toolbox/ , JavaScript, 488 linesDCC2/ codegen/ mex/ G/ html/ resources/ js/ coder_app.js - external/
DCC_toolbox/ , JavaScript, 150 linesDCC2/ codegen/ mex/ G/ html/ resources/ rtwannotate.js - external/
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DCC_toolbox/ , JavaScript, 559 linesDCC2/ codegen/ mex/ G/ html/ resources/ search.js - external/
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DCC_toolbox/ , MATLAB, 32 linesDCC2/ epsilonToY.m - external/
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binary_seq_to_string.m , MATLAB, 36 lines - external/
calc_lz_complexity.m , MATLAB, 400 lines - functions/
CopBET_DCC_entropy.m , MATLAB, 115 lines - functions/
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CopBET_temporal_entropy. , MATLAB, 277 lines, 1 matchm - functions/
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helper_functions/ , MATLAB, 78 linesCopBET_function_init.m - functions/
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permlme.R , R, 162 lines, 1 match - README.md, Text, 117 lines
Zenodo 19914432
Availability: 1 check, the latest on 27 September 2026: the link answers (HTTP 200)
- 27 September 2026: the link answers (HTTP 200)
Code availability
We shared relevant analysis scripts with original authors, hoping to ensure as much as possible that our computations aligned with original reports; we are thankful for the feedback we received. All functions used to derive entropy estimates from pre-processed data have been compiled into the Copenhagen Brain Entropy Toolbox (CopBET), a Matlab-based toolbox that can be found here: https://
Reproduced under the paper's license (CC BY), from the paper cited above.
Tracing map
Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.
What the map holds:
- 2 repositories of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
- 453 scripts, each with its path and the digest of its content;
- 17 matches between paragraphs of the paper and lines of the code (method lexical-v1);
- neither the text of the paper nor the code itself.
Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.
Data
No dataset and no data link were found in the paper.
Data availability
The data that support the findings of this study are available from the corresponding author upon request to the CIMBI database95. The raw neuroimaging data generated in this study have been deposited in the Cimbi database, https://
Reproduced under the paper's license (CC BY), from the paper cited above.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 1, 27 September 2026: the first record
Recorded: type, language, journal, volume, issue, pages, dates, 9 authors, 3 keywords, 11 MeSH terms, 5 funders, 93 references.
Cite
This paper
McCulloch, D. E.-W., Olsen, A. S., Ozenne, B., Larsen, K., Stenbæk, D. S., Armand, S., Madsen, M. K., Knudsen, G. M., & Fisher, P. M. (2026). Multi-metric evaluations of acute psychedelic effects on fMRI brain entropy. Nature communications, 17(1), 7940. https://
BibTeX
@article{mcculloch2026mu
author = {McCulloch, Drummond E-Wen and Olsen, Anders Stevnhoved and Ozenne, Brice and Larsen, Kristian and Stenbæk, Dea Siggaard and Armand, Sophia and Madsen, Martin Korsbak and Knudsen, Gitte Moos and Fisher, Patrick MacDonald},
title = {{Multi-metric evaluations of acute psychedelic effects on fMRI brain entropy}},
journal = {Nature communications},
year = {2026},
month = jun,
volume = {17},
number = {1},
pages = {7940},
publisher = {Nature Publishing Group},
issn = {2041-1723},
doi = {10.1038/
url = {https://
pmid = {42343098},
pmcid = {PMC13448839}
}
RIS
TY - JOUR
AU - McCulloch, Drummond E-Wen
AU - Olsen, Anders Stevnhoved
AU - Ozenne, Brice
AU - Larsen, Kristian
AU - Stenbæk, Dea Siggaard
AU - Armand, Sophia
AU - Madsen, Martin Korsbak
AU - Knudsen, Gitte Moos
AU - Fisher, Patrick MacDonald
TI - Multi-metric evaluations of acute psychedelic effects on fMRI brain entropy
T2 - Nature communications
J2 - Nat Commun
PY - 2026
DA - 2026/
VL - 17
IS - 1
SP - 7940
SN - 2041-1723
PB - Nature Publishing Group
DO - 10.1038/
UR - https://
LA - en
ER -
CSL-JSON
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