OSCR

The m⁶A reader YTHDF2 regulates mRNA transport and axon outgrowth in developing neurons.

Overview

Authors: Bonsang Koo1, Ajeet Kumar1, Huiseon Hwang1, Minyeong Park1, Sung-Min Lee1, Sung Ho Boo2, Ki-Heon Lee1, Ji-Hoon Moon1, Jaewon Yang1, Chan-Woo Park1, Saebom Lee1, Hee-Jung Jo3, Woo-il Kim3, Eunji Cho4, Hagyeong Lee4, Chang-Won Lee5, Jae-Sung Woo6, Jong Hyuk Yoon4, Yoon Ki Kim1,2,7, Ki-Jun Yoon1,7,8
ORCID iDs: Bonsang Koo, Huiseon Hwang, Sung-Min Lee, Jaewon Yang, Hee-Jung Jo, Eunji Cho, Chang-Won Lee, Jae-Sung Woo, Jong Hyuk Yoon, Yoon Ki Kim, Ki-Jun Yoon
  1. Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea
  2. KAIST InnoCORE AI-CRED Institute, KAIST, Daejeon, Republic of Korea
  3. CTX Co., Ltd., Seoul, Republic of Korea
  4. Neurodegenerative Diseases Research Group, Korea Brain Research Institute, Daegu, Republic of Korea
  5. Department of Life Sciences, Korea University, Seoul, Republic of Korea
  6. Center for Biomolecular and Cellular Structure, Institute for Basic Science, Daejeon, Republic of Korea
  7. Graduate School of Stem Cell and Regeneration Biology, KAIST, Daejeon, Republic of Korea
  8. KAIST Stem Cell Center, KAIST, Daejeon, Republic of Korea
Institutions: Korea Advanced Institute of Science and Technology (South Korea); Korea Brain Research Institute (South Korea); Korea University (South Korea); Institute for Basic Science (South Korea)
Journal: Nature communications, volume 17, issue 1, article 9255
Dates: received 24 September 2024; accepted 22 July 2026; published online 30 July 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41467-026-76161-8 · PMID 42669734 · PMCID PMC13526771 · OpenAlex W7171815941
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: mouse (organism)
Methods: Statistics, Evoked potentials, fMRI & imaging
Keywords: RNA modification, Neuronal development, Developmental neurogenesis
MeSH: Axons*, Nerve Tissue Proteins*, Neuronal Outgrowth*, Neurons*, RNA, Messenger*, RNA-Binding Proteins*, Adenosine, Animals, Epitranscriptome, Methyltransferases, Mice, Neurodevelopment, Neurogenesis, RNA Methylation, RNA Transport (* major topic)
Topic: RNA modifications and cancer (Molecular Biology, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Funding: National Research Foundation of Korea (NRF) (2020M3A9E403967022, RS-2024-00440778, RS-2024-00332454)
Citations: not cited yet (Europe PMC); 56 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Code and data availability statement

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Read it in the paper: doi.org/10.1038/s41467-026-76161-8.

Versions

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Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 20 authors, 3 keywords, 15 MeSH terms, 1 funder, 56 references.

Cite

This paper

Koo, B., Kumar, A., Hwang, H., Park, M., Lee, S.-M., Boo, S. H., Lee, K.-H., Moon, J.-H., Yang, J., Park, C.-W., Lee, S., Jo, H.-J., Kim, W.-i., Cho, E., Lee, H., Lee, C.-W., Woo, J.-S., Yoon, J. H., Kim, Y. K., & Yoon, K.-J. (2026). The m⁶A reader YTHDF2 regulates mRNA transport and axon outgrowth in developing neurons. Nature communications, 17(1), 9255. https://doi.org/10.1038/s41467-026-76161-8

BibTeX

@article{koo2026m6a,
author = {Koo, Bonsang and Kumar, Ajeet and Hwang, Huiseon and Park, Minyeong and Lee, Sung-Min and Boo, Sung Ho and Lee, Ki-Heon and Moon, Ji-Hoon and Yang, Jaewon and Park, Chan-Woo and Lee, Saebom and Jo, Hee-Jung and Kim, Woo-il and Cho, Eunji and Lee, Hagyeong and Lee, Chang-Won and Woo, Jae-Sung and Yoon, Jong Hyuk and Kim, Yoon Ki and Yoon, Ki-Jun},
title = {{The m⁶A reader YTHDF2 regulates mRNA transport and axon outgrowth in developing neurons}},
journal = {Nature communications},
year = {2026},
month = jul,
volume = {17},
number = {1},
pages = {9255},
publisher = {Nature Publishing Group},
issn = {2041-1723},
doi = {10.1038/s41467-026-76161-8},
url = {https://doi.org/10.1038/s41467-026-76161-8},
pmid = {42669734},
pmcid = {PMC13526771}
}

RIS

TY - JOUR
AU - Koo, Bonsang
AU - Kumar, Ajeet
AU - Hwang, Huiseon
AU - Park, Minyeong
AU - Lee, Sung-Min
AU - Boo, Sung Ho
AU - Lee, Ki-Heon
AU - Moon, Ji-Hoon
AU - Yang, Jaewon
AU - Park, Chan-Woo
AU - Lee, Saebom
AU - Jo, Hee-Jung
AU - Kim, Woo-il
AU - Cho, Eunji
AU - Lee, Hagyeong
AU - Lee, Chang-Won
AU - Woo, Jae-Sung
AU - Yoon, Jong Hyuk
AU - Kim, Yoon Ki
AU - Yoon, Ki-Jun
TI - The m⁶A reader YTHDF2 regulates mRNA transport and axon outgrowth in developing neurons
T2 - Nature communications
J2 - Nat Commun
PY - 2026
DA - 2026/07/30
VL - 17
IS - 1
SP - 9255
SN - 2041-1723
PB - Nature Publishing Group
DO - 10.1038/s41467-026-76161-8
UR - https://doi.org/10.1038/s41467-026-76161-8
LA - en
ER -

CSL-JSON

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