OSCR

Lewy pathology largely absent in prefrontal cortices of Parkinson's disease patients undergoing deep brain stimulation.

Overview

Authors: Ariela S. Buxbaum Grice1,2,3,4,5, Brian H. Kopell2,6,7,8,9, Klaudia F. Laborc2,4,5,10,11,12, Anina N. Lund1,2,3,4,5, Renata Gonzalez Chong3,4,5, Meredith Spadaccia6,7,8, Gerard Ona3, Girish Nadkarni5,13, John F. Crary2,4,5,10,11,12, Alexander W. Charney2,3,4,5, Noam D. Beckmann2,3,4,5,14
ORCID iDs: Renata Gonzalez Chong
14 affiliations
  1. Icahn School of Medicine at Mount Sinai,New York, NY USA
  2. Department of Neuroscience, Icahn School of Medicine at Mount Sinai,New York, NY USA
  3. Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai,New York, NY USA
  4. Friedman Brain Institute, Icahn School of Medicine at Mount Sinai,New York, NY USA
  5. Windreich Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai,New York, NY USA
  6. Center for Neuromodulation, Icahn School of Medicine at Mount Sinai,New York, NY USA
  7. Department of Neurosurgery, Icahn School of Medicine at Mount Sinai,New York, NY USA
  8. Department of Neurology, Icahn School of Medicine at Mount Sinai,New York, NY USA
  9. Department of Psychiatry, Icahn School of Medicine at Mount Sinai,New York, NY USA
  10. Department of Pathology, Molecular and Cell-based Medicine, Icahn School of Medicine at Mount Sinai,New York, NY USA
  11. Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai,New York, NY USA
  12. Ronald M. Loeb Center for Alzheimer’s Disease, Icahn School of Medicine at Mount Sinai,New York, NY USA
  13. The Hasso Plattner Institute for Digital Health at Mount Sinai,New York, NY USA
  14. Department of Medicine, Division of Data Driven and Digital Medicine (D3M), Icahn School of Medicine at Mount Sinai,New York, NY USA
Institutions: Icahn School of Medicine at Mount Sinai (United States); Mount Sinai Hospital (United States)
Journal: NPJ Parkinson's disease, volume 12, issue 1, article 152
Dates: received 22 September 2025; accepted 26 May 2026; published online 1 July 2026
Type: Brief report · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41531-026-01422-8 · PMID 42386762 · PMCID PMC13324718 · OpenAlex W7166879790
Open access: gold, a free copy (OpenAlex)
Status: code found, not verified yet
Categories: human (organism), Parkinson's (population), clinical / translational (subfield)
Methods: Connectivity, fMRI & imaging
Keywords: Diseases, Neurology, Neuroscience
Topic: Neurological disorders and treatments (Neurology, Medicine), according to OpenAlex
Funding: National Institute of Aging (R01AG069976); Michael J. Fox Foundation for Parkinson’s Research (Grant 18232)
Citations: not cited yet (Europe PMC); 24 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

No file of the authors' code could be read here: it is described below, and read at its source.

github.mountsinai.org/beckmann-lab/lbp_neuropath

License: none: the authors keep all their rights
State: unreachable at the last attempt, verified on 29 September 2026
Evidence: found in the paper
Software Heritage: not checked
Found in: “Code availability”
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 5 checks, the latest on 29 September 2026: unreachable at the last attempt
  • 29 September 2026: unreachable at the last attempt
  • 28 September 2026: unreachable at the last attempt
  • 28 September 2026: unreachable at the last attempt
  • 27 September 2026: unreachable at the last attempt
  • 27 September 2026: unreachable at the last attempt
At the source: github.mountsinai.org/Beckmann-Lab/LBP_Neuropath

Code availability statement

The paper has a code availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

Read it in the paper: doi.org/10.1038/s41531-026-01422-8.

Tracing map

Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.

What the map holds:

  • 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
  • 0 scripts, each with its path and the digest of its content;
  • no match between paragraphs and code yet;
  • neither the text of the paper nor the code itself.

Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

No dataset and no data link were found in the paper.

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the data are available on request

Read it in the paper: doi.org/10.1038/s41531-026-01422-8.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 11 authors, 3 keywords, 2 funders, 23 references.

Cite

This paper

Buxbaum Grice, A. S., Kopell, B. H., Laborc, K. F., Lund, A. N., Gonzalez Chong, R., Spadaccia, M., Ona, G., Nadkarni, G., Crary, J. F., Charney, A. W., & Beckmann, N. D. (2026). Lewy pathology largely absent in prefrontal cortices of Parkinson's disease patients undergoing deep brain stimulation. NPJ Parkinson's disease, 12(1), 152. https://doi.org/10.1038/s41531-026-01422-8

BibTeX

@article{buxbaumgrice2026lewy,
author = {Buxbaum Grice, Ariela S. and Kopell, Brian H. and Laborc, Klaudia F. and Lund, Anina N. and Gonzalez Chong, Renata and Spadaccia, Meredith and Ona, Gerard and Nadkarni, Girish and Crary, John F. and Charney, Alexander W. and Beckmann, Noam D.},
title = {{Lewy pathology largely absent in prefrontal cortices of Parkinson's disease patients undergoing deep brain stimulation}},
journal = {NPJ Parkinson's disease},
year = {2026},
month = jul,
volume = {12},
number = {1},
pages = {152},
publisher = {Nature Publishing Group},
issn = {2373-8057},
doi = {10.1038/s41531-026-01422-8},
url = {https://doi.org/10.1038/s41531-026-01422-8},
pmid = {42386762},
pmcid = {PMC13324718}
}

RIS

TY - JOUR
AU - Buxbaum Grice, Ariela S.
AU - Kopell, Brian H.
AU - Laborc, Klaudia F.
AU - Lund, Anina N.
AU - Gonzalez Chong, Renata
AU - Spadaccia, Meredith
AU - Ona, Gerard
AU - Nadkarni, Girish
AU - Crary, John F.
AU - Charney, Alexander W.
AU - Beckmann, Noam D.
TI - Lewy pathology largely absent in prefrontal cortices of Parkinson's disease patients undergoing deep brain stimulation
T2 - NPJ Parkinson's disease
J2 - NPJ Parkinsons Dis
PY - 2026
DA - 2026/07/01
VL - 12
IS - 1
SP - 152
SN - 2373-8057
PB - Nature Publishing Group
DO - 10.1038/s41531-026-01422-8
UR - https://doi.org/10.1038/s41531-026-01422-8
LA - en
ER -

CSL-JSON

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