Non-severe burn injury leads to sustained molecular changes in the brain in a murine model.

Overview

Authors: Amira Allahham^1,2, Nutan Chaudhari³, Sarah Walsh⁴, Blair Z. Johnson^1,2, Samantha Lodge⁵, Drew Hall⁵, Zhenjun Deng⁶, Rongchang Yang⁵, Monique J. Ryan⁵, Phillip E. Melton^7,8, Jennifer Rodger^9,10, Fiona M. Wood^1,2,11, Luke Whiley^5,12, Mark W. Fear^1,2, Andrew W. Stevenson^1,2

ORCID iDs: Amira Allahham, Sarah Walsh, Samantha Lodge, Monique J. Ryan, Jennifer Rodger, Luke Whiley, Mark W. Fear, Andrew W. Stevenson

Institutions: The University of Western Australia (Australia); Fiona Wood Foundation; Murdoch University (Australia); King Edward Memorial Hospital (Australia); Southern University of Science and Technology (China); University of Tasmania (Australia); Perron Institute for Neurological and Translational Science (Australia); Curtin University (Australia)

Journal: Scientific reports, volume 16, issue 1, article 17989

Dates: received 17 November 2025; accepted 23 February 2026; published online 18 April 2026

Type: Research article · Language: English

License: CC BY-NC-ND

Identifiers: DOI 10.1038/s41598-026-41942-0 · PMID 42000783 · PMCID PMC13249875 · OpenAlex W7154839343

Open access: gold, a free copy (OpenAlex)

Status: data only

Categories: genetics / omics (modality), human (organism), mouse (organism), other condition (population), depression (population)

Methods: Statistics, Smoothing, state filtering, decompositions

Keywords: Burn injury, Non-severe burn injury, Mental health, Neurodegeneration, Inflammation, Biomarkers, Diseases, Medical research, Neuroscience

MeSH: Brain*, Burns*, Animals, Anxiety, Behavior, Animal, Depression, Disease Models, Animal, Hippocampus, Male, Mice, Mice, Inbred C57BL, Transcriptome (* major topic)

Topic: Burn Injury Management and Outcomes (Epidemiology, Medicine), according to OpenAlex

Funding: B.S

Citations: not cited yet (Europe PMC); 60 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper links to its data, not to its authors' code: see the Data section.

Tracing map

A tracing map links a paper to the code its authors published: this paper has none, so it has no map.

Data

Data links

ncbi.nlm.nih.gov/geo/query, NCBI; found in “Data availability”

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

it points to a dataset: NCBI

Read it in the paper: doi.org/10.1038/s41598-026-41942-0.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 29 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 15 authors, 9 keywords, 12 MeSH terms, 1 funder, 57 references.

Cite

This paper

Allahham, A., Chaudhari, N., Walsh, S., Johnson, B. Z., Lodge, S., Hall, D., Deng, Z., Yang, R., Ryan, M. J., Melton, P. E., Rodger, J., Wood, F. M., Whiley, L., Fear, M. W., & Stevenson, A. W. (2026). Non-severe burn injury leads to sustained molecular changes in the brain in a murine model. Scientific reports, 16(1), 17989. https://doi.org/10.1038/s41598-026-41942-0

BibTeX

@article{allahham2026non, author = {Allahham, Amira and Chaudhari, Nutan and Walsh, Sarah and Johnson, Blair Z. and Lodge, Samantha and Hall, Drew and Deng, Zhenjun and Yang, Rongchang and Ryan, Monique J. and Melton, Phillip E. and Rodger, Jennifer and Wood, Fiona M. and Whiley, Luke and Fear, Mark W. and Stevenson, Andrew W.}, title = {{Non-severe burn injury leads to sustained molecular changes in the brain in a murine model}}, journal = {Scientific reports}, year = {2026}, month = apr, volume = {16}, number = {1}, pages = {17989}, publisher = {Nature Publishing Group}, issn = {2045-2322}, doi = {10.1038/s41598-026-41942-0}, url = {https://doi.org/10.1038/s41598-026-41942-0}, pmid = {42000783}, pmcid = {PMC13249875} }

RIS

TY - JOUR AU - Allahham, Amira AU - Chaudhari, Nutan AU - Walsh, Sarah AU - Johnson, Blair Z. AU - Lodge, Samantha AU - Hall, Drew AU - Deng, Zhenjun AU - Yang, Rongchang AU - Ryan, Monique J. AU - Melton, Phillip E. AU - Rodger, Jennifer AU - Wood, Fiona M. AU - Whiley, Luke AU - Fear, Mark W. AU - Stevenson, Andrew W. TI - Non-severe burn injury leads to sustained molecular changes in the brain in a murine model T2 - Scientific reports J2 - Sci Rep PY - 2026 DA - 2026/04/18 VL - 16 IS - 1 SP - 17989 SN - 2045-2322 PB - Nature Publishing Group DO - 10.1038/s41598-026-41942-0 UR - https://doi.org/10.1038/s41598-026-41942-0 LA - en ER -

CSL-JSON

{ "id": "10.1038/s41598-026-41942-0", "type": "article-journal", "title": "Non-severe burn injury leads to sustained molecular changes in the brain in a murine model", "container-title": "Scientific reports", "author": [ { "family": "Allahham", "given": "Amira" }, { "family": "Chaudhari", "given": "Nutan" }, { "family": "Walsh", "given": "Sarah" }, { "family": "Johnson", "given": "Blair Z." }, { "family": "Lodge", "given": "Samantha" }, { "family": "Hall", "given": "Drew" }, { "family": "Deng", "given": "Zhenjun" }, { "family": "Yang", "given": "Rongchang" }, { "family": "Ryan", "given": "Monique J." }, { "family": "Melton", "given": "Phillip E." }, { "family": "Rodger", "given": "Jennifer" }, { "family": "Wood", "given": "Fiona M." }, { "family": "Whiley", "given": "Luke" }, { "family": "Fear", "given": "Mark W." }, { "family": "Stevenson", "given": "Andrew W." } ], "container-title-short": "Sci Rep", "volume": "16", "issue": "1", "page": "17989", "DOI": "10.1038/s41598-026-41942-0", "PMID": "42000783", "PMCID": "PMC13249875", "ISSN": "2045-2322", "publisher": "Nature Publishing Group", "URL": "https://doi.org/10.1038/s41598-026-41942-0", "language": "en", "issued": { "date-parts": [ [ 2026, 4, 18 ] ] } }

Contribute

The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.

Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.

Request its removal

To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).

Discussion, reproductions, activity

Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.

Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.

Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.