Regional tissue oxygenation during high-intensity exercise following voluntary isocapnic hyperpnea versus inspiratory threshold loading in endurance-trained individuals: a randomized controlled trial.

Overview

Authors: Daniel Ramos–López¹, Raúl Caulier–Cisterna², Andrés Vega–Moraga², Fúlvia B Manchado–Gobatto^3,4, Luigi Gabrielli–Nervi^5,6, Hugo E Verdejo^5,6, Vitor A Lira⁷, Maximiliano Espinosa–Ramírez⁷, Karol Ramírez–Parada⁸, Matías Crisosto–Ramos¹, Antonio Escobar–Neicun¹, Amalia Matus–Santa Cruz¹, Savka Miranda–Osorio¹, Kevin Parra–Huenchuleo¹, Aracelly Pérez–Caro¹, Sebastián Podestá–Oyarzun¹, Oscar F Araneda⁹, Felipe Contreras–Briceño¹⁰

Institutions: Pontificia Universidad Católica de Chile (Chile); Metropolitan University of Technology (Chile); Universidade Estadual de Campinas (UNICAMP) (Brazil); Hospital Clínico de la Universidad Católica (Chile); Advanced Center for Chronic Diseases (Chile); University of Iowa (United States); Universidad Andrés Bello (Chile); Universidad de Los Andes, Chile (Chile); University of O'Higgins (Chile)

Journal: Scientific reports, volume 16, issue 1, article 10732

Dates: received 20 December 2025; accepted 24 March 2026; published online 28 March 2026

Type: Research article · Language: English

License: CC BY-NC-ND

Identifiers: DOI 10.1038/s41598-026-46153-1 · PMID 41904324 · PMCID PMC13039917 · OpenAlex W7142244516

Open access: gold, a free copy (OpenAlex)

Status: code on request (how the code is found and verified)

Categories: fNIRS (modality), human (organism)

Methods: Spectral & time-frequency, Statistics, fMRI & imaging, Physiology & signal measures

Keywords: Health care, Medical research, Physiology

MeSH: Endurance Training*, Exercise*, Oxygen*, Oxygen Consumption*, Physical Endurance*, Adult, Female, Humans, Male, Prefrontal Cortex, Respiratory Muscles, Spectroscopy, Near-Infrared, Young Adult (* major topic)

Topic: Respiratory Support and Mechanisms (Pulmonary and Respiratory Medicine, Medicine), according to OpenAlex

Funding: Agencia Nacional de Investigación y Desarrollo (11250867)

Citations: not cited yet (Europe PMC); 46 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Code and data availability statement

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it says that the data are available on request
it says that the code is available on request

Read it in the paper: doi.org/10.1038/s41598-026-46153-1.

Versions

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Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 18 authors, 3 keywords, 13 MeSH terms, 1 funder, 45 references.

Cite

This paper

Ramos–López, D., Caulier–Cisterna, R., Vega–Moraga, A., Manchado–Gobatto, F. B., Gabrielli–Nervi, L., Verdejo, H. E., Lira, V. A., Espinosa–Ramírez, M., Ramírez–Parada, K., Crisosto–Ramos, M., Escobar–Neicun, A., Matus–Santa Cruz, A., Miranda–Osorio, S., Parra–Huenchuleo, K., Pérez–Caro, A., Podestá–Oyarzun, S., Araneda, O. F., & Contreras–Briceño, F. (2026). Regional tissue oxygenation during high-intensity exercise following voluntary isocapnic hyperpnea versus inspiratory threshold loading in endurance-trained individuals: a randomized controlled trial. Scientific reports, 16(1), 10732. https://doi.org/10.1038/s41598-026-46153-1

BibTeX

@article{ramoslopez2026regional, author = {Ramos–López, Daniel and Caulier–Cisterna, Raúl and Vega–Moraga, Andrés and Manchado–Gobatto, Fúlvia B and Gabrielli–Nervi, Luigi and Verdejo, Hugo E and Lira, Vitor A and Espinosa–Ramírez, Maximiliano and Ramírez–Parada, Karol and Crisosto–Ramos, Matías and Escobar–Neicun, Antonio and Matus–Santa Cruz, Amalia and Miranda–Osorio, Savka and Parra–Huenchuleo, Kevin and Pérez–Caro, Aracelly and Podestá–Oyarzun, Sebastián and Araneda, Oscar F and Contreras–Briceño, Felipe}, title = {{Regional tissue oxygenation during high-intensity exercise following voluntary isocapnic hyperpnea versus inspiratory threshold loading in endurance-trained individuals: a randomized controlled trial}}, journal = {Scientific reports}, year = {2026}, month = mar, volume = {16}, number = {1}, pages = {10732}, publisher = {Nature Publishing Group}, issn = {2045-2322}, doi = {10.1038/s41598-026-46153-1}, url = {https://doi.org/10.1038/s41598-026-46153-1}, pmid = {41904324}, pmcid = {PMC13039917} }

RIS

TY - JOUR AU - Ramos–López, Daniel AU - Caulier–Cisterna, Raúl AU - Vega–Moraga, Andrés AU - Manchado–Gobatto, Fúlvia B AU - Gabrielli–Nervi, Luigi AU - Verdejo, Hugo E AU - Lira, Vitor A AU - Espinosa–Ramírez, Maximiliano AU - Ramírez–Parada, Karol AU - Crisosto–Ramos, Matías AU - Escobar–Neicun, Antonio AU - Matus–Santa Cruz, Amalia AU - Miranda–Osorio, Savka AU - Parra–Huenchuleo, Kevin AU - Pérez–Caro, Aracelly AU - Podestá–Oyarzun, Sebastián AU - Araneda, Oscar F AU - Contreras–Briceño, Felipe TI - Regional tissue oxygenation during high-intensity exercise following voluntary isocapnic hyperpnea versus inspiratory threshold loading in endurance-trained individuals: a randomized controlled trial T2 - Scientific reports J2 - Sci Rep PY - 2026 DA - 2026/03/28 VL - 16 IS - 1 SP - 10732 SN - 2045-2322 PB - Nature Publishing Group DO - 10.1038/s41598-026-46153-1 UR - https://doi.org/10.1038/s41598-026-46153-1 LA - en ER -

CSL-JSON

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