OSCR

Integrative bioinformatics analysis unveils neuro-cancer crosstalk-related genes and establishes prognostic risk model in Glioblastoma.

Overview

Authors: Lin Zeng1, Dingjun Li1, Mengyu Du1, Tao Wu1, Yun Liao1, Yuxing Huang1, Xingyu Liao1
  1. Department of Neurosurgery, Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu, 610075 Sichuan China
Journal: Scientific reports, volume 16, issue 1, article 21699
Dates: received 23 November 2025; accepted 29 April 2026; published online 12 May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41598-026-51730-5 · PMID 42120472 · PMCID PMC13357736 · OpenAlex W7160933645
Open access: gold, a free copy (OpenAlex)
Status: data only
Categories: genetics / omics (modality), human (organism), other condition (population)
Methods: Statistics, Smoothing, state filtering, decompositions, Machine learning, Connectivity
Keywords: Glioblastoma, Neuro-cancer crosstalk, Single-cell RNA sequencing, Prognostic model, NGFR, L1CAM, Immune infiltration, Cancer, Computational biology and bioinformatics, Oncology
MeSH: Brain Neoplasms*, Computational Biology*, Glioblastoma*, Biomarkers, Tumor, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Gene Regulatory Networks, Humans, Molecular Docking Simulation, Neural Cell Adhesion Molecule L1, Prognosis, Single-Cell Analysis, Transcriptome (* major topic)
Topic: Glioma Diagnosis and Treatment (Genetics, Medicine), according to OpenAlex
Citations: not cited yet (Europe PMC); 39 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it points to a dataset: NCBI

Read it in the paper: doi.org/10.1038/s41598-026-51730-5.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 7 authors, 10 keywords, 13 MeSH terms, 39 references.

Cite

This paper

Zeng, L., Li, D., Du, M., Wu, T., Liao, Y., Huang, Y., & Liao, X. (2026). Integrative bioinformatics analysis unveils neuro-cancer crosstalk-related genes and establishes prognostic risk model in Glioblastoma. Scientific reports, 16(1), 21699. https://doi.org/10.1038/s41598-026-51730-5

BibTeX

@article{zeng2026integrative,
author = {Zeng, Lin and Li, Dingjun and Du, Mengyu and Wu, Tao and Liao, Yun and Huang, Yuxing and Liao, Xingyu},
title = {{Integrative bioinformatics analysis unveils neuro-cancer crosstalk-related genes and establishes prognostic risk model in Glioblastoma}},
journal = {Scientific reports},
year = {2026},
month = may,
volume = {16},
number = {1},
pages = {21699},
publisher = {Nature Publishing Group},
issn = {2045-2322},
doi = {10.1038/s41598-026-51730-5},
url = {https://doi.org/10.1038/s41598-026-51730-5},
pmid = {42120472},
pmcid = {PMC13357736}
}

RIS

TY - JOUR
AU - Zeng, Lin
AU - Li, Dingjun
AU - Du, Mengyu
AU - Wu, Tao
AU - Liao, Yun
AU - Huang, Yuxing
AU - Liao, Xingyu
TI - Integrative bioinformatics analysis unveils neuro-cancer crosstalk-related genes and establishes prognostic risk model in Glioblastoma
T2 - Scientific reports
J2 - Sci Rep
PY - 2026
DA - 2026/05/12
VL - 16
IS - 1
SP - 21699
SN - 2045-2322
PB - Nature Publishing Group
DO - 10.1038/s41598-026-51730-5
UR - https://doi.org/10.1038/s41598-026-51730-5
LA - en
ER -

CSL-JSON

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"ISSN": "2045-2322",
"publisher": "Nature Publishing Group",
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"language": "en",
"issued": {
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}

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