OSCR

Aging macaques bridge the translational gap in perivascular space biology.

Overview

Authors: William A Liguore1, Daniel L Schwartz2,3, Juan Piantino4, Avanthika Rajendran5, Greg Jensen5, Joshua A Karpf1,2, Mykyta M Chernov1, Randall L Woltjer2,3, Steven G Kohama1, Lisa C Silbert2,3,6, Alison R Weiss1,2
  1. Oregon National Primate Research Center, Beaverton, OR USA
  2. Oregon Health & Science University, Portland, OR USA
  3. Layton Oregon Alzheimers Disease Research Center, Portland, OR USA
  4. Division of Child Neurology Department of Pediatrics, Oregon Health and Science University, Portland, OR USA
  5. Reed College, Portland, OR USA
  6. Portland Veterans Affairs Health Care System, Portland, OR USA
Institutions: Oregon National Primate Research Center (United States); Oregon Health & Science University (United States); Reed College (United States); VA Portland Health Care System (United States)
Journal: Scientific reports, volume 16, issue 1, article 27346
Dates: received 3 February 2026; accepted 7 May 2026; published online 15 June 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s41598-026-52797-w · PMID 42297855 · PMCID PMC13530188 · OpenAlex W7164846832
Open access: gold, a free copy (OpenAlex)
Status: code verified
Categories: structural MRI / diffusion (modality), human (organism), non-human primate (organism), clinical / translational (subfield)
Methods: Statistics, Connectivity, fMRI & imaging
Keywords: Rhesus macaque, Perivascular space, Aging, Glymphatic, Anatomy, Neuroscience
MeSH: Aging*, Brain*, Glymphatic System*, Animals, Female, Humans, Macaca mulatta, Magnetic Resonance Imaging, Male (* major topic)
Topic: Cerebrospinal fluid and hydrocephalus (Cellular and Molecular Neuroscience, Neuroscience), according to OpenAlex
Funding: National Institutes of Health (AG078407, OD011092, HL173372, AG066518); NHLBI NIH HHS (R01 HL173372); NIH HHS (P51 OD011092, AG078407, AG066518, HL173372, OD011092); NIA NIH HHS (K01 AG078407, P30 AG066518)
Citations: not cited yet (Europe PMC); 48 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

No file of the authors' code could be read here: it is described below, and read at its source.

ohsu.edu/alzheimers-disease-research-center/data-resources

License: none: the authors keep all their rights
State: the link answers, verified on 27 September 2026
Evidence: the link answers
Software Heritage: not checked
Found in: “Data availability”
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Availability: 1 check, the latest on 27 September 2026: the link answers (HTTP 200)
  • 27 September 2026: the link answers (HTTP 200)

The paper's code and data availability statement is in the Data section.

Tracing map

Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.

What the map holds:

  • 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
  • 0 scripts, each with its path and the digest of its content;
  • no match between paragraphs and code yet;
  • neither the text of the paper nor the code itself.

Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

No dataset and no data link were found in the paper.

Code and data availability statement

The paper has a code and data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

Read it in the paper: doi.org/10.1038/s41598-026-52797-w.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 11 authors, 6 keywords, 9 MeSH terms, 4 funders, 48 references.

Cite

This paper

Liguore, W. A., Schwartz, D. L., Piantino, J., Rajendran, A., Jensen, G., Karpf, J. A., Chernov, M. M., Woltjer, R. L., Kohama, S. G., Silbert, L. C., & Weiss, A. R. (2026). Aging macaques bridge the translational gap in perivascular space biology. Scientific reports, 16(1), 27346. https://doi.org/10.1038/s41598-026-52797-w

BibTeX

@article{liguore2026aging,
author = {Liguore, William A and Schwartz, Daniel L and Piantino, Juan and Rajendran, Avanthika and Jensen, Greg and Karpf, Joshua A and Chernov, Mykyta M and Woltjer, Randall L and Kohama, Steven G and Silbert, Lisa C and Weiss, Alison R},
title = {{Aging macaques bridge the translational gap in perivascular space biology}},
journal = {Scientific reports},
year = {2026},
month = jun,
volume = {16},
number = {1},
pages = {27346},
publisher = {Nature Publishing Group},
issn = {2045-2322},
doi = {10.1038/s41598-026-52797-w},
url = {https://doi.org/10.1038/s41598-026-52797-w},
pmid = {42297855},
pmcid = {PMC13530188}
}

RIS

TY - JOUR
AU - Liguore, William A
AU - Schwartz, Daniel L
AU - Piantino, Juan
AU - Rajendran, Avanthika
AU - Jensen, Greg
AU - Karpf, Joshua A
AU - Chernov, Mykyta M
AU - Woltjer, Randall L
AU - Kohama, Steven G
AU - Silbert, Lisa C
AU - Weiss, Alison R
TI - Aging macaques bridge the translational gap in perivascular space biology
T2 - Scientific reports
J2 - Sci Rep
PY - 2026
DA - 2026/06/15
VL - 16
IS - 1
SP - 27346
SN - 2045-2322
PB - Nature Publishing Group
DO - 10.1038/s41598-026-52797-w
UR - https://doi.org/10.1038/s41598-026-52797-w
LA - en
ER -

CSL-JSON

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The tracing map gets a citation of its own once an author has validated it and it has a DOI.

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