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Early life chronic stress-disrupted activity of the dorsal raphe nucleus selectively drives behavioral impairments.

Overview

Authors: Zoltan K Varga1, Archana Golla2, Florence Kermen1,2
ORCID iDs: Zoltan K Varga, Florence Kermen
  1. Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
  2. Department of Biology, Faculty of Natural Sciences, Norwegian University of Science and Technology, Trondheim, Norway
Institutions: University of Copenhagen (Denmark); Norwegian University of Science and Technology (Norway)
Journal: Communications biology, volume 9, issue 1, article 642
Dates: received 1 October 2025; accepted 2 March 2026; published online 20 March 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s42003-026-09855-w · PMID 41862617 · PMCID PMC13168280 · OpenAlex W7139013415
Open access: gold, a free copy (OpenAlex)
Status: data only (how the code is found and verified)
Categories: zebrafish (organism), developmental (subfield)
Methods: Spectral & time-frequency, Statistics, Connectivity, Single-unit activity, calcium imaging
Keywords: Stress and resilience, Emotion
MeSH: Behavior, Animal*, Dorsal Raphe Nucleus*, Stress, Physiological*, Stress, Psychological*, Animals, Reflex, Startle, Serotonergic Neurons, Serotonin, Zebrafish (* major topic)
Topic: Stress Responses and Cortisol (Behavioral Neuroscience, Neuroscience), according to OpenAlex
Citations: cited by 3 papers (Europe PMC); 89 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper links to its data and to no code of its authors: see the Data section.

Tracing map

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Data

Datasets cited

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it points to a dataset: Zenodo 18657361
  • it says that the data are available on request

Read it in the paper: doi.org/10.1038/s42003-026-09855-w.

Versions

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Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 3 authors, 2 keywords, 9 MeSH terms, 86 references.

Cite

This paper

Varga, Z. K., Golla, A., & Kermen, F. (2026). Early life chronic stress-disrupted activity of the dorsal raphe nucleus selectively drives behavioral impairments. Communications biology, 9(1), 642. https://doi.org/10.1038/s42003-026-09855-w

BibTeX

@article{varga2026early,
author = {Varga, Zoltan K and Golla, Archana and Kermen, Florence},
title = {{Early life chronic stress-disrupted activity of the dorsal raphe nucleus selectively drives behavioral impairments}},
journal = {Communications biology},
year = {2026},
month = mar,
volume = {9},
number = {1},
pages = {642},
publisher = {Nature Publishing Group},
issn = {2399-3642},
doi = {10.1038/s42003-026-09855-w},
url = {https://doi.org/10.1038/s42003-026-09855-w},
pmid = {41862617},
pmcid = {PMC13168280}
}

RIS

TY - JOUR
AU - Varga, Zoltan K
AU - Golla, Archana
AU - Kermen, Florence
TI - Early life chronic stress-disrupted activity of the dorsal raphe nucleus selectively drives behavioral impairments
T2 - Communications biology
J2 - Commun Biol
PY - 2026
DA - 2026/03/20
VL - 9
IS - 1
SP - 642
SN - 2399-3642
PB - Nature Publishing Group
DO - 10.1038/s42003-026-09855-w
UR - https://doi.org/10.1038/s42003-026-09855-w
LA - en
ER -

CSL-JSON

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