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Inhibiting glucocorticoid receptors enhances adult spinal cord neural stem cell activity and improves outcomes in spinal cord injury.

Overview

Authors: Xuefeng Zhang1,2, Siyuan Zhou1, Shengyu Tang1,2, Xiaotong Hou1, Yonghui Cai1, Changlong Hu1,2
  1. School of Life Sciences, Shanghai Xuhui District Central Hospital, Fudan University,Shanghai, P.R. China
  2. International Human Phenome Institute (Shanghai), Shanghai, P.R. China
Institutions: Fudan University (China)
Journal: Communications biology, volume 9, issue 1, article 652
Dates: received 4 September 2025; accepted 9 March 2026; published online 23 March 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s42003-026-09901-7 · PMID 41872297 · PMCID PMC13172350 · OpenAlex W7140140371
Open access: gold, a free copy (OpenAlex)
Categories: mouse (organism), other condition (population)
Methods: Statistics
Keywords: Neural stem cells, Adult neurogenesis
MeSH: Neural Stem Cells*, Receptors, Glucocorticoid*, Spinal Cord*, Spinal Cord Injuries*, Animals, Cell Differentiation, Cell Proliferation, Female, Glucocorticoids, Mice, Mice, Inbred C57BL, Signal Transduction (* major topic)
Topic: Neurogenesis and neuroplasticity mechanisms (Developmental Neuroscience, Neuroscience), according to OpenAlex
Funding: 1. the Science and Technology Innovation 2030 Brain Science and Brain-Inspired Intelligence Project (2021ZD0201301) 2. the National Key Research and Development Program of China (2022YFC3602702)
Citations: not cited yet (Europe PMC); 60 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

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Code and data availability statement

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  • it points to a dataset: NCBI

Read it in the paper: doi.org/10.1038/s42003-026-09901-7.

Versions

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Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 6 authors, 2 keywords, 12 MeSH terms, 1 funder, 60 references.

Cite

This paper

Zhang, X., Zhou, S., Tang, S., Hou, X., Cai, Y., & Hu, C. (2026). Inhibiting glucocorticoid receptors enhances adult spinal cord neural stem cell activity and improves outcomes in spinal cord injury. Communications biology, 9(1), 652. https://doi.org/10.1038/s42003-026-09901-7

BibTeX

@article{zhang2026inhibiting,
author = {Zhang, Xuefeng and Zhou, Siyuan and Tang, Shengyu and Hou, Xiaotong and Cai, Yonghui and Hu, Changlong},
title = {{Inhibiting glucocorticoid receptors enhances adult spinal cord neural stem cell activity and improves outcomes in spinal cord injury}},
journal = {Communications biology},
year = {2026},
month = mar,
volume = {9},
number = {1},
pages = {652},
publisher = {Nature Publishing Group},
issn = {2399-3642},
doi = {10.1038/s42003-026-09901-7},
url = {https://doi.org/10.1038/s42003-026-09901-7},
pmid = {41872297},
pmcid = {PMC13172350}
}

RIS

TY - JOUR
AU - Zhang, Xuefeng
AU - Zhou, Siyuan
AU - Tang, Shengyu
AU - Hou, Xiaotong
AU - Cai, Yonghui
AU - Hu, Changlong
TI - Inhibiting glucocorticoid receptors enhances adult spinal cord neural stem cell activity and improves outcomes in spinal cord injury
T2 - Communications biology
J2 - Commun Biol
PY - 2026
DA - 2026/03/23
VL - 9
IS - 1
SP - 652
SN - 2399-3642
PB - Nature Publishing Group
DO - 10.1038/s42003-026-09901-7
UR - https://doi.org/10.1038/s42003-026-09901-7
LA - en
ER -

CSL-JSON

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