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Elovanoid neuroprotection targets cell transcriptomics and proteomics to sustain synaptic integrity after brain injury.

Overview

Authors: Brian L Giles1, Surjyadipta Bhattacharjee1, Jeff X Ji1, Pranab K Mukherjee1, Ludmila Belayev1, Carlos M Vieira1, Nicolas G Bazan1
  1. Neuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA USA
Journal: Communications biology, volume 9, issue 1, article 948
Dates: received 11 November 2025; accepted 16 March 2026; published online 10 April 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s42003-026-09931-1 · PMID 41963623 · PMCID PMC13365245 · OpenAlex W7152975298
Open access: gold, a free copy (OpenAlex)
Status: code on request
Categories: genetics / omics (modality), mouse (organism), cellular / molecular (subfield)
Methods: Statistics, Smoothing, state filtering, decompositions, Machine learning
Keywords: Neuroscience, Diseases of the nervous system
MeSH: Brain Injuries*, Brain Injuries, Traumatic*, Neuroprotection*, Neuroprotective Agents*, Proteomics*, Synapses*, Transcriptome*, Animals, Gene Expression Profiling, Mice, Mitochondria, Neurons (* major topic)
Topic: Neuroinflammation and Neurodegeneration Mechanisms (Neurology, Neuroscience), according to OpenAlex
Funding: U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) (R01NS138259); U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (R01NS138259); NIGMS NIH HHS (P20 GM121288); NINDS NIH HHS (R01 NS138259); Eye, Ear, Nose & Throat (EENT) Foundation of New Orleans
Citations: cited by 1 paper (Europe PMC); 113 references in the paper
Research resources: RRID:SCR_024440

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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  • it says that the code is available on request

Read it in the paper: doi.org/10.1038/s42003-026-09931-1.

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Data

Datasets cited

Data availability statement

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Read it in the paper: doi.org/10.1038/s42003-026-09931-1.

Versions

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Version 1, 29 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 7 authors, 2 keywords, 12 MeSH terms, 5 funders, 113 references, 1 RRID.

Cite

This paper

Giles, B. L., Bhattacharjee, S., Ji, J. X., Mukherjee, P. K., Belayev, L., Vieira, C. M., & Bazan, N. G. (2026). Elovanoid neuroprotection targets cell transcriptomics and proteomics to sustain synaptic integrity after brain injury. Communications biology, 9(1), 948. https://doi.org/10.1038/s42003-026-09931-1

BibTeX

@article{giles2026elovanoid,
author = {Giles, Brian L and Bhattacharjee, Surjyadipta and Ji, Jeff X and Mukherjee, Pranab K and Belayev, Ludmila and Vieira, Carlos M and Bazan, Nicolas G},
title = {{Elovanoid neuroprotection targets cell transcriptomics and proteomics to sustain synaptic integrity after brain injury}},
journal = {Communications biology},
year = {2026},
month = apr,
volume = {9},
number = {1},
pages = {948},
publisher = {Nature Publishing Group},
issn = {2399-3642},
doi = {10.1038/s42003-026-09931-1},
url = {https://doi.org/10.1038/s42003-026-09931-1},
pmid = {41963623},
pmcid = {PMC13365245}
}

RIS

TY - JOUR
AU - Giles, Brian L
AU - Bhattacharjee, Surjyadipta
AU - Ji, Jeff X
AU - Mukherjee, Pranab K
AU - Belayev, Ludmila
AU - Vieira, Carlos M
AU - Bazan, Nicolas G
TI - Elovanoid neuroprotection targets cell transcriptomics and proteomics to sustain synaptic integrity after brain injury
T2 - Communications biology
J2 - Commun Biol
PY - 2026
DA - 2026/04/10
VL - 9
IS - 1
SP - 948
SN - 2399-3642
PB - Nature Publishing Group
DO - 10.1038/s42003-026-09931-1
UR - https://doi.org/10.1038/s42003-026-09931-1
LA - en
ER -

CSL-JSON

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}

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