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FLP-15 functions through the GPCR NPR-3 to regulate local and global search behaviours in Caenorhabditis elegans.

Overview

Authors: Umer Saleem Bhat1,2, Siju Surendran1,3, Sharanya H1, Jun Liu4, Yun Xu4, Namra Tasnim1,3, Mohd Faraz Abbas1, Ashwani Bhardwaj2,5, Monika Scholz4, Kavita Babu1
ORCID iDs: Umer Saleem Bhat, Sharanya H, Jun Liu, Monika Scholz, Kavita Babu
  1. Centre for Neuroscience, Indian Institute of Science (IISc),Bangalore, India
  2. Department of Biological Sciences, Indian Institute of Science Education and Research (IISER),Mohali, India
  3. Université de Fribourg,Fribourg, Switzerland
  4. Max Planck Research Group Neural Information Flow, Max Planck Institute for Neurobiology of Behavior – Caesar,Bonn, Germany
  5. Regional Forensic Science Laboratory, Dharamshala, India
Institutions: Indian Institute of Science Bangalore (India); Indian Institute of Science Education and Research Mohali (India); University of Fribourg (Switzerland); Max Planck Institute for Neurobiology of Behavior – caesar (Germany)
Journal: Communications biology, volume 9, issue 1, article 923
Dates: received 22 September 2025; accepted 23 April 2026; published online 5 May 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s42003-026-10188-x · PMID 42082704 · PMCID PMC13346541 · OpenAlex W4410202958
Open access: gold, a free copy (OpenAlex)
Preprint: doi:10.1101/2025.05.02.651881
Status: data only
Categories: C. elegans (organism), cellular / molecular (subfield)
Methods: Statistics, Evoked potentials
Keywords: Molecular neuroscience, Neurophysiology
MeSH: Behavior, Animal*, Caenorhabditis elegans*, Caenorhabditis elegans Proteins*, Neuropeptides*, Receptors, G-Protein-Coupled*, Receptors, Neuropeptide Y*, Animals, Dopamine, Feeding Behavior, Mutation (* major topic)
Topic: Genetics, Aging, and Longevity in Model Organisms (Aging, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Funding: Department of Biotechnology, Ministry of Science and Technology (DBT) (BT/PR24038/BRB/10/1693/2018, BT/HRD-NBA-NWB/38/2019-20); wellcome trust dbt india alliance (IA/S/19/2/504649); DST | Science and Engineering Research Board (SERB) (CRG/2023/001950, SPG/2022/000182)
Citations: cited by 2 papers (Europe PMC); 60 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it points to a dataset: OSF kbavs
  • it says that the data are available on request

Read it in the paper: doi.org/10.1038/s42003-026-10188-x.

Versions

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Version 1, 28 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 10 authors, 2 keywords, 10 MeSH terms, 3 funders, 60 references.

Cite

This paper

Bhat, U. S., Surendran, S., H, S., Liu, J., Xu, Y., Tasnim, N., Abbas, M. F., Bhardwaj, A., Scholz, M., & Babu, K. (2026). FLP-15 functions through the GPCR NPR-3 to regulate local and global search behaviours in Caenorhabditis elegans. Communications biology, 9(1), 923. https://doi.org/10.1038/s42003-026-10188-x

BibTeX

@article{bhat2026flp,
author = {Bhat, Umer Saleem and Surendran, Siju and H, Sharanya and Liu, Jun and Xu, Yun and Tasnim, Namra and Abbas, Mohd Faraz and Bhardwaj, Ashwani and Scholz, Monika and Babu, Kavita},
title = {{FLP-15 functions through the GPCR NPR-3 to regulate local and global search behaviours in Caenorhabditis elegans}},
journal = {Communications biology},
year = {2026},
month = may,
volume = {9},
number = {1},
pages = {923},
publisher = {Nature Publishing Group},
issn = {2399-3642},
doi = {10.1038/s42003-026-10188-x},
url = {https://doi.org/10.1038/s42003-026-10188-x},
pmid = {42082704},
pmcid = {PMC13346541}
}

RIS

TY - JOUR
AU - Bhat, Umer Saleem
AU - Surendran, Siju
AU - H, Sharanya
AU - Liu, Jun
AU - Xu, Yun
AU - Tasnim, Namra
AU - Abbas, Mohd Faraz
AU - Bhardwaj, Ashwani
AU - Scholz, Monika
AU - Babu, Kavita
TI - FLP-15 functions through the GPCR NPR-3 to regulate local and global search behaviours in Caenorhabditis elegans
T2 - Communications biology
J2 - Commun Biol
PY - 2026
DA - 2026/05/05
VL - 9
IS - 1
SP - 923
SN - 2399-3642
PB - Nature Publishing Group
DO - 10.1038/s42003-026-10188-x
UR - https://doi.org/10.1038/s42003-026-10188-x
LA - en
ER -

CSL-JSON

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