OSCR

Focused ultrasound-induced cavitation in a human brain microphysiological system produces injury signaling biomarkers consistent with blast trauma.

Overview

Authors: Peter Hsi1,2,3, Tyler Gerhardson1, Jennifer L Walker1, Ernest Kim1, Olivia T Spagnola1, Brett Isenberg1, Anthony Quinnert1, David L Kaplan3, Vishal Tandon1
  1. Bioengineering Division, The Charles Stark Draper Laboratory Inc., Cambridge, MA USA
  2. Draper Scholar, The Charles Stark Draper Laboratory Inc., Cambridge, MA USA
  3. Tufts University, Medford, MA USA
Institutions: Tufts University (United States); Draper Laboratory (United States)
Journal: npj biomedical innovations, volume 3, issue 1, article 36
Dates: received 10 March 2026; accepted 30 April 2026; published online 11 June 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1038/s44385-026-00090-w · PMID 42277372 · PMCID PMC13260352 · OpenAlex W7164405219
Open access: gold, a free copy (OpenAlex)
Status: code on request
Categories: other (modality), human (organism)
Methods: Statistics, Preprocessing, Evoked potentials, fMRI & imaging, Single-unit activity, calcium imaging, Machine learning
Keywords: Biological techniques, Cell biology, Engineering, Neurology, Neuroscience
Topic: Ultrasound and Hyperthermia Applications (Biomedical Engineering, Engineering), according to OpenAlex
Funding: U. S. Department of Defense (W911NF-23-1-0276); NIH HHS (P41EB027062)
Citations: not cited yet (Europe PMC); 86 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

The paper says that its authors' code is available on request: it was not published with the paper, so there is nothing to verify.

Code availability statement

The paper has a code availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

  • it says that the code is available on request

Read it in the paper: doi.org/10.1038/s44385-026-00090-w.

Tracing map

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Data

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Data availability statement

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  • it says that the data are available on request

Read it in the paper: doi.org/10.1038/s44385-026-00090-w.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 9 authors, 5 keywords, 2 funders, 82 references.

Cite

This paper

Hsi, P., Gerhardson, T., Walker, J. L., Kim, E., Spagnola, O. T., Isenberg, B., Quinnert, A., Kaplan, D. L., & Tandon, V. (2026). Focused ultrasound-induced cavitation in a human brain microphysiological system produces injury signaling biomarkers consistent with blast trauma. npj biomedical innovations, 3(1), 36. https://doi.org/10.1038/s44385-026-00090-w

BibTeX

@article{hsi2026focused,
author = {Hsi, Peter and Gerhardson, Tyler and Walker, Jennifer L and Kim, Ernest and Spagnola, Olivia T and Isenberg, Brett and Quinnert, Anthony and Kaplan, David L and Tandon, Vishal},
title = {{Focused ultrasound-induced cavitation in a human brain microphysiological system produces injury signaling biomarkers consistent with blast trauma}},
journal = {npj biomedical innovations},
year = {2026},
month = jun,
volume = {3},
number = {1},
pages = {36},
publisher = {Nature Publishing Group},
issn = {3005-1444},
doi = {10.1038/s44385-026-00090-w},
url = {https://doi.org/10.1038/s44385-026-00090-w},
pmid = {42277372},
pmcid = {PMC13260352}
}

RIS

TY - JOUR
AU - Hsi, Peter
AU - Gerhardson, Tyler
AU - Walker, Jennifer L
AU - Kim, Ernest
AU - Spagnola, Olivia T
AU - Isenberg, Brett
AU - Quinnert, Anthony
AU - Kaplan, David L
AU - Tandon, Vishal
TI - Focused ultrasound-induced cavitation in a human brain microphysiological system produces injury signaling biomarkers consistent with blast trauma
T2 - npj biomedical innovations
J2 - NPJ Biomed Innov
PY - 2026
DA - 2026/06/11
VL - 3
IS - 1
SP - 36
SN - 3005-1444
PB - Nature Publishing Group
DO - 10.1038/s44385-026-00090-w
UR - https://doi.org/10.1038/s44385-026-00090-w
LA - en
ER -

CSL-JSON

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"author": [
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"container-title-short": "NPJ Biomed Innov",
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"PMID": "42277372",
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"ISSN": "3005-1444",
"publisher": "Nature Publishing Group",
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"language": "en",
"issued": {
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}

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