OSCR

Biologically grounded on-chip model identifies selective topographic reorganization within hyperexcitable corticostriatal networks.

Overview

Authors: Maxime Poinsot1, Marine Dos Santos1, Baptiste Marthy1,2, Ana Borges-Correia1, Eduardo Gascon1, Benoit Charlot3, Maxime Cazorla1
  1. Aix Marseille Université, CNRS, Institut de Neurosciences de la Timone, Marseille FR-13005, France
  2. Aix Marseille Université, Centrale Med, CNRS, Institut Fresnel, Marseille FR-13013, France
  3. Université Montpellier, CNRS, Institut d’Electronique et des Systèmes, Montpellier FR-34000, France
Dates: received 27 May 2025; accepted 11 February 2026; published online 24 March 2026; in print 31 March 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1073/pnas.2513459123 · PMID 41875163 · PMCID PMC13038058 · OpenAlex W7140236720
Open access: hybrid, a free copy (OpenAlex)
Categories: mouse (organism), systems (subfield)
Methods: Statistics, Connectivity, Evoked potentials
Keywords: corticostriatal pathways, neuronal connectivity, in vitro platforms, brain-on-chip, axon growth
MeSH: Cerebral Cortex*, Corpus Striatum*, Models, Neurological*, Nerve Net*, Animals, Axons, Mice, Neural Pathways, Neurodevelopment, Neurons (* major topic)
Journal subjects: Biological Sciences, Neuroscience, Physical Sciences, Engineering
Topic: Neural dynamics and brain function (Cognitive Neuroscience, Neuroscience), according to OpenAlex
Funding: Agence Nationale de la Recherche (ANR-19-CE16-0027, ANR-22-CE17-0034, AMX-19-IET-004, ANR-17-EURE-0029); Association Nationale de la Recherche et de la Technologie (ANRT-CIFRE-2021/1043); Association France Alzheimer (2021-6239)
Citations: not cited yet (Europe PMC); 53 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Code and data availability statement

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Read it in the paper: doi.org/10.1073/pnas.2513459123.

Versions

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Version 1, 30 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 7 authors, 5 keywords, 10 MeSH terms, 3 funders, 51 references.

Cite

This paper

Poinsot, M., Dos Santos, M., Marthy, B., Borges-Correia, A., Gascon, E., Charlot, B., & Cazorla, M. (2026). Biologically grounded on-chip model identifies selective topographic reorganization within hyperexcitable corticostriatal networks. Proceedings of the National Academy of Sciences of the United States of America, 123(13), e2513459123. https://doi.org/10.1073/pnas.2513459123

BibTeX

@article{poinsot2026biologically,
author = {Poinsot, Maxime and Dos Santos, Marine and Marthy, Baptiste and Borges-Correia, Ana and Gascon, Eduardo and Charlot, Benoit and Cazorla, Maxime},
title = {{Biologically grounded on-chip model identifies selective topographic reorganization within hyperexcitable corticostriatal networks}},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
year = {2026},
month = mar,
volume = {123},
number = {13},
pages = {e2513459123},
publisher = {National Academy of Sciences},
issn = {0027-8424},
doi = {10.1073/pnas.2513459123},
url = {https://doi.org/10.1073/pnas.2513459123},
pmid = {41875163},
pmcid = {PMC13038058}
}

RIS

TY - JOUR
AU - Poinsot, Maxime
AU - Dos Santos, Marine
AU - Marthy, Baptiste
AU - Borges-Correia, Ana
AU - Gascon, Eduardo
AU - Charlot, Benoit
AU - Cazorla, Maxime
TI - Biologically grounded on-chip model identifies selective topographic reorganization within hyperexcitable corticostriatal networks
T2 - Proceedings of the National Academy of Sciences of the United States of America
J2 - Proc Natl Acad Sci U S A
PY - 2026
DA - 2026/03/24
VL - 123
IS - 13
SP - e2513459123
SN - 0027-8424
PB - National Academy of Sciences
DO - 10.1073/pnas.2513459123
UR - https://doi.org/10.1073/pnas.2513459123
LA - en
ER -

CSL-JSON

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