OSCR

Uncoupling neocortical neuron fate and migration via a Let-7-RBX2 axis.

Overview

Authors: Steven C Decker1, Keiko Hino1, Anna La Torre1, Sergi Simó1
ORCID iDs: Steven C Decker, Anna La Torre, Sergi Simó
  1. Department of Cell Biology and Human Anatomy, University of California Davis, Davis, CA 95616
Institutions: University of California, Davis (United States)
Journal: Proceedings of the National Academy of Sciences of the United States of America, volume 123, issue 17, article e2528396123
Dates: received 8 October 2025; accepted 25 March 2026; published online 21 April 2026; in print 28 April 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1073/pnas.2528396123 · PMID 42012943 · PMCID PMC13123820 · OpenAlex W4414304786
Open access: hybrid, a free copy (OpenAlex)
Preprint: doi:10.1101/2025.09.11.675676
Status: data only
Categories: mouse (organism), developmental (subfield)
Methods: Evoked potentials, Smoothing, state filtering, decompositions
Keywords: cortical development, neurogenesis, cell fate, let-7, RBX2
MeSH: Cell Movement*, MicroRNAs*, Neocortex*, Neurons*, Ubiquitin-Protein Ligases*, 3' Untranslated Regions, Animals, Cell Differentiation, Mice, Nerve Tissue Proteins, Neurogenesis, Reelin Protein, Signal Transduction (* major topic)
Topic: Neurogenesis and neuroplasticity mechanisms (Developmental Neuroscience, Neuroscience), according to OpenAlex
Funding: NINDS NIH HHS (R01 NS131375, R01 NS109176, R21 NS133564); HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) (R01 NS43205, R01 NS109176, R21 NS133564, R01 NS131375)
Citations: cited by 2 papers (Europe PMC); 62 references in the paper
Research resources: Switzerland RRID:Addgene_117055

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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The paper's code and data availability statement is in the Data section.

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Data

Datasets cited

Code and data availability statement

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Read it in the paper: doi.org/10.1073/pnas.2528396123.

Versions

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Version 1, 29 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 4 authors, 5 keywords, 13 MeSH terms, 2 funders, 62 references, 1 RRID.

Cite

This paper

Decker, S. C., Hino, K., La Torre, A., & Simó, S. (2026). Uncoupling neocortical neuron fate and migration via a Let-7-RBX2 axis. Proceedings of the National Academy of Sciences of the United States of America, 123(17), e2528396123. https://doi.org/10.1073/pnas.2528396123

BibTeX

@article{decker2026uncoupling,
author = {Decker, Steven C and Hino, Keiko and La Torre, Anna and Simó, Sergi},
title = {{Uncoupling neocortical neuron fate and migration via a Let-7-RBX2 axis}},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
year = {2026},
month = apr,
volume = {123},
number = {17},
pages = {e2528396123},
publisher = {National Academy of Sciences},
issn = {0027-8424},
doi = {10.1073/pnas.2528396123},
url = {https://doi.org/10.1073/pnas.2528396123},
pmid = {42012943},
pmcid = {PMC13123820}
}

RIS

TY - JOUR
AU - Decker, Steven C
AU - Hino, Keiko
AU - La Torre, Anna
AU - Simó, Sergi
TI - Uncoupling neocortical neuron fate and migration via a Let-7-RBX2 axis
T2 - Proceedings of the National Academy of Sciences of the United States of America
J2 - Proc Natl Acad Sci U S A
PY - 2026
DA - 2026/04/21
VL - 123
IS - 17
SP - e2528396123
SN - 0027-8424
PB - National Academy of Sciences
DO - 10.1073/pnas.2528396123
UR - https://doi.org/10.1073/pnas.2528396123
LA - en
ER -

CSL-JSON

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"PMID": "42012943",
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