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Use of the dTAG system in vivo to degrade CDK2 and CDK5 in adult mice and explore potential safety liabilities.

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Overview

Authors: Paul Yenerall, Tae Sung, Kiran Palyada, Jessie Qian, Seda Arat, Steven W Kumpf, Shih-Wen Wang, Kathleen Biddle, Carlos Esparza, Stephanie Chang, Wesley Scott, Walter Collette, Taylor-Symon Winrow, Tim Affolter, Norimitsu Shirai, Stephane Thibault, Julia Wang, Ling Liu, Mary Bauchmann, Jessica Frey
and 9 other authorsStefanus Steyn, Aida Sacaan, Allison Vitsky, Youngwook Ahn, Tom Paul, Lawrence Lum, Jon Oyer, Amy Yang, Wenyue Hu
Published: 1 June 2023
Type: Research article
License: CC BY-NC-ND

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