OSCR

Glucocorticoid Receptor Translational Isoforms Generate Unique Glucocorticoid Responses in the Mouse Brain.

Overview

Authors: Robert H Oakley1, Tatsuya Sueyoshi1, Sivapriya Ramamoorthy1, Viktoriya D Nikolova2, David R Goulding3, Jianying Li4, Manas K Ray5, Sheryl S Moy2, John A Cidlowski1
ORCID iDs: Robert H Oakley
  1. Molecular and Cellular Biology Laboratory, NIEHS, NIH, DHHS, Research Triangle Park, North Carolina, USA
  2. Department of Psychiatry and Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
  3. Comparative Medicine Branch, NIEHS, NIH, DHHS, Research Triangle Park, North Carolina, USA
  4. Biostatistics and Computational Biology Branch, NIEHS, NIH, DHHS, Research Triangle Park, North Carolina, USA
  5. Gene Editing and Mouse Model Core, NIEHS, NIH, DHHS, Research Triangle Park, North Carolina, USA
Dates: received 18 March 2026; accepted 3 June 2026; published online 10 June 2026; in print 30 June 2026
Type: Research article · Language: English
License: CC BY-NC-ND
Identifiers: DOI 10.1096/fj.202601316r · PMID 42268251 · PMCID PMC13252007 · OpenAlex W7164127350
Open access: hybrid, a free copy (OpenAlex)
Status: data only
Categories: mouse (organism), cellular / molecular (subfield)
Methods: Statistics
Keywords: behavior, glucocorticoid receptors, glucocorticoids, heterodimers, hippocampus, homodimers, protein isoforms
MeSH: Brain*, Glucocorticoids*, Receptors, Glucocorticoid*, Animals, Dexamethasone, Gene Knock-In Techniques, Hippocampus, Male, Mice, Mice, Inbred C57BL, Protein Isoforms (* major topic)
Topic: Estrogen and related hormone effects (Genetics, Biochemistry, Genetics and Molecular Biology), according to OpenAlex
Funding: Intramural Research Program of the NIH, National Institute of Environmental Health Sciences (NIEHS) (ZIAES090057, ZICES102425); NICHD NIH HHS (P50 HD103573); Eunice Kennedy Shriver National Institute of Child Health and Human Development (P50 HD103573)
Citations: not cited yet (Europe PMC); 42 references in the paper
Research resources: Blots were incubated with anti‐GR RRID:AB_11179215, anti‐actin RRID:AB_2223041, RRID:AB_2535758, goat anti‐mouse IRDye800‐conjugated RRID:AB_621842, Fifty thousand HEK293 cells RRID:CVCL_0045, RRID:IMSR_JAX:000664, RRID:IMSR_TAC:7089, RRID:SCR_002798, RRID:SCR_004463, RRID:SCR_006442, Ingenuity pathway analysis (IPA RRID:SCR_008653, MA) and Statview RRID:SCR_017411

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

Read it in the paper: doi.org/10.1096/fj.202601316r.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 2, 28 September 2026

  • Publisher: n/a → Wiley

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 9 authors, 7 keywords, 11 MeSH terms, 3 funders, 42 references, 12 RRIDs.

Cite

This paper

Oakley, R. H., Sueyoshi, T., Ramamoorthy, S., Nikolova, V. D., Goulding, D. R., Li, J., Ray, M. K., Moy, S. S., & Cidlowski, J. A. (2026). Glucocorticoid Receptor Translational Isoforms Generate Unique Glucocorticoid Responses in the Mouse Brain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 40(12), e72040. https://doi.org/10.1096/fj.202601316r

BibTeX

@article{oakley2026glucocorticoid,
author = {Oakley, Robert H and Sueyoshi, Tatsuya and Ramamoorthy, Sivapriya and Nikolova, Viktoriya D and Goulding, David R and Li, Jianying and Ray, Manas K and Moy, Sheryl S and Cidlowski, John A},
title = {{Glucocorticoid Receptor Translational Isoforms Generate Unique Glucocorticoid Responses in the Mouse Brain}},
journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
year = {2026},
month = jun,
volume = {40},
number = {12},
pages = {e72040},
publisher = {Wiley},
issn = {0892-6638},
doi = {10.1096/fj.202601316r},
url = {https://doi.org/10.1096/fj.202601316r},
pmid = {42268251},
pmcid = {PMC13252007}
}

RIS

TY - JOUR
AU - Oakley, Robert H
AU - Sueyoshi, Tatsuya
AU - Ramamoorthy, Sivapriya
AU - Nikolova, Viktoriya D
AU - Goulding, David R
AU - Li, Jianying
AU - Ray, Manas K
AU - Moy, Sheryl S
AU - Cidlowski, John A
TI - Glucocorticoid Receptor Translational Isoforms Generate Unique Glucocorticoid Responses in the Mouse Brain
T2 - FASEB journal : official publication of the Federation of American Societies for Experimental Biology
J2 - FASEB J
PY - 2026
DA - 2026/06/01
VL - 40
IS - 12
SP - e72040
SN - 0892-6638
PB - Wiley
DO - 10.1096/fj.202601316r
UR - https://doi.org/10.1096/fj.202601316r
LA - en
ER -

CSL-JSON

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