Successful MRgFUS VIM Thalamotomy for Essential Tremor Nearby Cavernous Malformation: Image Case Report.
Overview
- Division of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
- Harquail Centre for Neuromodulation, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
- LC Campbell Cognitive Neurology Research Unit, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
- Imaging Research, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
- Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Abstract
Introduction: Essential tremor (ET) is the most common movement disorder, severe and refractory cases of which may benefit from neurosurgical interventions such as magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy. Cerebrovascular diseases are generally considered a contraindication for MRgFUS due to concerns of intracerebral hemorrhage; however, they are a heterogenous group of lesions, with distinct clinical behaviors. We present the first reported case of successful MRgFUS-thalamotomy for ET in a patient with a contralateral thalamic cerebral cavernous malformation (CCM).
Case Presentation: A 78-year-old male with refractory bilateral upper limb postural/
Discussion: The distinct histopathological features of CCMs, including slow flow and the absence of arterial feeders, produce a more favorable profile compared to other cerebrovascular lesions. Avoidance of direct ultrasound trajectories through the malformation, the use of conservative temperatures, and continuous clinical monitoring were critical to ensuring procedural safety and efficacy. This case demonstrates the feasibility of MRgFUS-thalamotomy in carefully selected patients with coexisting CCMs.
Reproduced under the paper's license (CC BY-NC), from the paper cited above.
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Data
Datasets cited
- figshare:32780262, at figshare; found in DataCite
Data Availability Statement
The data supporting the findings of this study are not publicly accessible due to confidentiality constraints associated with patient images, which are considered protected health information. However, these data can be obtained from the corresponding author N.L. upon direct request.
Reproduced under the paper's license (CC BY-NC), from the paper cited above.
Versions
The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.
Version 2, 28 September 2026
- Publisher: n/a → Karger Publishers
Version 1, 27 September 2026: the first record
Recorded: type, language, journal, pages, dates, 7 authors, 4 keywords, 9 references.
Cite
This paper
Favi Bocca, L., Davidson, B., Lam, B., Endre, R., Huang, Y., Hamani, C., & Lipsman, N. (2026). Successful MRgFUS VIM Thalamotomy for Essential Tremor Nearby Cavernous Malformation: Image Case Report. Stereotactic and functional neurosurgery, 1-4. https://
BibTeX
@article{favibocca2026su
author = {Favi Bocca, Leonardo and Davidson, Benjamin and Lam, Benjamin and Endre, Ruby and Huang, Yuexi and Hamani, Clement and Lipsman, Nir},
title = {{Successful MRgFUS VIM Thalamotomy for Essential Tremor Nearby Cavernous Malformation: Image Case Report}},
journal = {Stereotactic and functional neurosurgery},
year = {2026},
month = jun,
pages = {1--4},
publisher = {Karger Publishers},
issn = {1011-6125},
doi = {10.1159/
url = {https://
pmid = {42348493},
pmcid = {PMC13450976}
}
RIS
TY - JOUR
AU - Favi Bocca, Leonardo
AU - Davidson, Benjamin
AU - Lam, Benjamin
AU - Endre, Ruby
AU - Huang, Yuexi
AU - Hamani, Clement
AU - Lipsman, Nir
TI - Successful MRgFUS VIM Thalamotomy for Essential Tremor Nearby Cavernous Malformation: Image Case Report
T2 - Stereotactic and functional neurosurgery
J2 - Stereotact Funct Neurosurg
PY - 2026
DA - 2026/
SP - 1
EP - 4
SN - 1011-6125
PB - Karger Publishers
DO - 10.1159/
UR - https://
LA - en
ER -
CSL-JSON
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"language": "en",
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