OSCR

Social approach-avoidance conflict: Behavioural, emotional, and neural correlates along a depression-social anxiety spectrum.

Code ↔ Paper

2 matches between paragraphs of the paper and lines of its authors' code, computed by the harvester (lexical-v1). Click a colored paragraph or line to see its counterpart.

The 2 matches · 1 of them tie a paragraph to a whole file, not to given lines: a weak match, whose lines are not tinted
  1. [1] § Methods › fMRI image acquisition and data analyses ↔ fMRI analysis/Preprocessing/PREPROCESAMIENTO_job.m, the whole file · a weak match · score 0.69 · realigned image, preprocessing, FWHM, MNI, SPM12, smoothed
  2. [2] § Methods › Emotional response questionnaires ↔ Behavioral analysis/figuras_emocionales_notas.R, lines 22–94 · score 0.51 · 1–2, 3–4, discrete, grade, feedback, emotions

Paper

Loaded from Europe PMC by your browser, not stored by OSCR: doi.org · Europe PMC

The paper is loaded when this pane is shown.

The authors' code

MATLAB · 99 lines · 7.5 KB · no license · 1 match

This file is not shown here: its repository has no license, so its authors keep all their rights to it. Your browser cannot show it from its source either: OSF does not let the page of another site read its files.

It can be read at the source: fMRI analysis/Preprocessing/PREPROCESAMIENTO_job.m.

Overview

Authors: Francisco Cervantes Constantino1, Alejo Acuña1,2, Catalina Fernandez1, Michelle Guillen1, Laura Mendaro1, Antonella Brandani1, Sebastián Morales1,3, Alfonso Pérez1, Javier Mattos4, Enrique Cuña4, Margarita García-Fontes4, Álvaro Cabana1,3,5, Jorge L. Armony6, Michael Gaebler7, Victoria B. Gradin1,3
ORCID iDs: Enrique Cuña, Victoria B. Gradin
  1. Center for Basic Research in Psychology (CIBPsi), Facultad de Psicología, Universidad de la República, Montevideo, Uruguay
  2. Sección Neurociencias, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay
  3. Instituto de Fundamentos y Métodos en Psicología, Facultad de Psicología, Universidad de la República, Montevideo, Uruguay
  4. Centro Uruguayo de Imagenología Molecular (CUDIM), Montevideo, Uruguay
  5. Centro Interdisciplinario de Ciencia de Datos y Aprendizaje Automático (CICADA), Universidad de la República, Montevideo, Uruguay
  6. Department of Psychology, McGill University, Montreal, Canada
  7. Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
Institutions: Universidad de la República de Uruguay (Uruguay); Centro Uruguayo de Imagenología Molecular (Uruguay); McGill University (Canada); Max Planck Institute for Human Cognitive and Brain Sciences (Germany)
Journal: Imaging neuroscience (Cambridge, Mass.), volume 4, article IMAG.a.1363
Dates: received 19 February 2026; accepted 11 August 2026; published online 10 September 2026
Type: Research article · Language: English
License: CC BY
Identifiers: DOI 10.1162/imag.a.1363 · PMID 42729754 · PMCID PMC13563531 · OpenAlex W7203833449
Open access: diamond, a free copy (OpenAlex)
Status: code verified
Categories: fMRI (modality), human (organism), other condition (population), depression (population), cognitive (subfield)
Methods: Connectivity, Statistics, Smoothing, state filtering, decompositions, Preprocessing, Machine learning, fMRI & imaging
Keywords: approach-avoidance conflict, social interactions, depression, social anxiety, event-related fMRI
MeSH: Anxiety*, Avoidance Learning*, Brain*, Conflict, Psychological*, Depression*, Emotions*, Phobia, Social*, Social Behavior*, Adult, Brain Mapping, Female, Humans, Magnetic Resonance Imaging, Male, Reward, Young Adult (* major topic)
Topic: Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes (Experimental and Cognitive Psychology, Psychology), according to OpenAlex
Funding: Universidad de la República; Agencia Nacional de Investigación e Innovación; Programa de Desarrollo de las Ciencias Básicas (PEDECIBA)
Citations: not cited yet (Europe PMC); 93 references in the paper

Abstract

Approach-avoidance conflict, in which the same option entails both rewarding and aversive consequences, has been proposed as a key process in internalizing disorders such as depression and social anxiety. Yet, human paradigms that model approach-avoidance conflict and link it to brain function remain scarce. In particular, it has been emphasized the need for studying this conflict in social contexts. We developed a Social Approach-Avoidance Conflict (SAAC) task that involved a social evaluative demand manipulation, and combined it with functional magnetic resonance imaging (fMRI) in 135 young adults. On each trial, participants decided whether to accept a variable reward at the cost of increasing the presence of more or less demanding judges in a future public speaking evaluation, or to avoid and receive a minimal default reward. Depression and social anxiety (D-SA) symptoms were summarized into a single continuous dimension derived from principal component analysis of psychological questionnaires. Behaviourally, higher payments increased approach, whereas higher judge ranks increased negative affect and avoidance. Higher D-SA scores were associated with reduced positive and heightened negative emotional responses to higher-rank judges, stronger preferences for low-rank judges, and greater avoidance of high-rank judges. Neurally, increasing judge rank recruited the dmPFC/dACC during approach decisions, and higher D-SA symptoms were associated with stronger responses in these regions. Increasing payment during approach engaged dmPFC/vmPFC, PCC, and posterior insula, and these reward-related responses were attenuated at higher D-SA levels. In conclusion, internalizing symptoms of depression and social anxiety are associated with a bias in emotional and behavioural responses when a reward competes with a social evaluative threat. At the neural level, internalizing symptoms were associated with an enhanced aversive/conflict signalling in the dmPFC/dACC, and with reduced reward-related activity. Findings shed light on the mechanisms underlying costly social avoidance in internalizing disorders.

Reproduced under the paper's license (CC BY), from the paper cited above.

Repository

Its files are read in the Code ↔ Paper reader above, with 2 matches between paragraphs and lines of code.

OSF uq837

License: none: the authors keep all their rights
State: the link answers, verified on 26 September 2026
Evidence: files inventoried
Languages: MATLAB (15), R (3)
Size: 18 files, 18 scripts
Software Heritage: not checked
Found in: “Data and Code Availability”
Not found: README, license file, CITATION.cff, environment file, tests, continuous integration, documentation
Tools: SPM (12 files), cowplot (3 files), ggplot2 (3 files), lme4 (3 files), lmerTest (3 files), reshape2 (3 files), tidyverse (3 files), car (2 files), ggpubr (2 files)
Availability: 1 check, the latest on 26 September 2026: the link answers (HTTP 200)
  • 26 September 2026: the link answers (HTTP 200)
18 files, to read at the source

This repository has no license: its authors keep all rights. Read it at the source.

At the source: osf.io/uq837/

The paper's code and data availability statement is in the Data section.

Tracing map

Proposed by the machine: these links were found in the paper and verified at the source, without human review. The map will receive a Zenodo DOI once one of the paper's authors has validated it with their ORCID.

What the map holds:

  • 1 repository of the authors' code, each at its verified commit, with its license and how the link was found in the paper;
  • 18 scripts, each with its path and the digest of its content;
  • 2 matches between paragraphs of the paper and lines of the code (method lexical-v1);
  • neither the text of the paper nor the code itself.

Its JSON (tracing-map.json) is deposited on Zenodo with its DOI once the map is validated.

Data

No dataset and no data link were found in the paper.

Data and Code Availability

The data underlying this article cannot be shared publicly because it would require participants to sign an additional consent form, which is not possible to implement at the moment. The code used for the analysis is available at https://osf.io/uq837/

Reproduced under the paper's license (CC BY), from the paper cited above.

Versions

The history of this record: each version stored by the harvester or made by a correction of its authors or of the maintainers of its code, and what changed in its facts. The texts of the paper (its abstract, its availability statements) are not part of it; versions that changed only those are not listed.

Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, pages, dates, 15 authors, 5 keywords, 16 MeSH terms, 3 funders, 92 references.

Cite

This paper

Cervantes Constantino, F., Acuña, A., Fernandez, C., Guillen, M., Mendaro, L., Brandani, A., Morales, S., Pérez, A., Mattos, J., Cuña, E., García-Fontes, M., Cabana, Á., Armony, J. L., Gaebler, M., & Gradin, V. B. (2026). Social approach-avoidance conflict: Behavioural, emotional, and neural correlates along a depression-social anxiety spectrum. Imaging neuroscience (Cambridge, Mass.), 4, IMAG.a.1363. https://doi.org/10.1162/imag.a.1363

BibTeX

@article{cervantesconstantino2026social,
author = {Cervantes Constantino, Francisco and Acuña, Alejo and Fernandez, Catalina and Guillen, Michelle and Mendaro, Laura and Brandani, Antonella and Morales, Sebastián and Pérez, Alfonso and Mattos, Javier and Cuña, Enrique and García-Fontes, Margarita and Cabana, Álvaro and Armony, Jorge L. and Gaebler, Michael and Gradin, Victoria B.},
title = {{Social approach-avoidance conflict: Behavioural, emotional, and neural correlates along a depression-social anxiety spectrum}},
journal = {Imaging neuroscience (Cambridge, Mass.)},
year = {2026},
month = sep,
volume = {4},
pages = {IMAG.a.1363},
publisher = {MIT Press},
issn = {2837-6056},
doi = {10.1162/imag.a.1363},
url = {https://doi.org/10.1162/imag.a.1363},
pmid = {42729754},
pmcid = {PMC13563531}
}

RIS

TY - JOUR
AU - Cervantes Constantino, Francisco
AU - Acuña, Alejo
AU - Fernandez, Catalina
AU - Guillen, Michelle
AU - Mendaro, Laura
AU - Brandani, Antonella
AU - Morales, Sebastián
AU - Pérez, Alfonso
AU - Mattos, Javier
AU - Cuña, Enrique
AU - García-Fontes, Margarita
AU - Cabana, Álvaro
AU - Armony, Jorge L.
AU - Gaebler, Michael
AU - Gradin, Victoria B.
TI - Social approach-avoidance conflict: Behavioural, emotional, and neural correlates along a depression-social anxiety spectrum
T2 - Imaging neuroscience (Cambridge, Mass.)
J2 - Imaging Neurosci (Camb)
PY - 2026
DA - 2026/09/10
VL - 4
SP - IMAG.a.1363
SN - 2837-6056
PB - MIT Press
DO - 10.1162/imag.a.1363
UR - https://doi.org/10.1162/imag.a.1363
LA - en
ER -

CSL-JSON

{
"id": "10.1162/imag.a.1363",
"type": "article-journal",
"title": "Social approach-avoidance conflict: Behavioural, emotional, and neural correlates along a depression-social anxiety spectrum",
"container-title": "Imaging neuroscience (Cambridge, Mass.)",
"author": [
{
"family": "Cervantes Constantino",
"given": "Francisco"
},
{
"family": "Acuña",
"given": "Alejo"
},
{
"family": "Fernandez",
"given": "Catalina"
},
{
"family": "Guillen",
"given": "Michelle"
},
{
"family": "Mendaro",
"given": "Laura"
},
{
"family": "Brandani",
"given": "Antonella"
},
{
"family": "Morales",
"given": "Sebastián"
},
{
"family": "Pérez",
"given": "Alfonso"
},
{
"family": "Mattos",
"given": "Javier"
},
{
"family": "Cuña",
"given": "Enrique"
},
{
"family": "García-Fontes",
"given": "Margarita"
},
{
"family": "Cabana",
"given": "Álvaro"
},
{
"family": "Armony",
"given": "Jorge L."
},
{
"family": "Gaebler",
"given": "Michael"
},
{
"family": "Gradin",
"given": "Victoria B."
}
],
"container-title-short": "Imaging Neurosci (Camb)",
"volume": "4",
"page": "IMAG.a.1363",
"DOI": "10.1162/imag.a.1363",
"PMID": "42729754",
"PMCID": "PMC13563531",
"ISSN": "2837-6056",
"publisher": "MIT Press",
"URL": "https://doi.org/10.1162/imag.a.1363",
"language": "en",
"issued": {
"date-parts": [
[
2026,
9,
10
]
]
}
}

The tracing map gets a citation of its own once an author has validated it and it has a DOI.

Similar papers

The papers with a page that share the most with this one: the tools found in their code, their categories, datasets, cited references and authors, the rarest counting most.

[1] doi:10.1073/pnas.2606871123 [code]
Oxytocin modulates the neurocomputational mechanisms engaged in learning rank relationships in social networks.
Journal: Proceedings of the National Academy of Sciences of the United States of America
In common: car, lmerTest, lme4, 5 other tools, 1 reference
[2] doi:10.1016/j.neuroimage.2026.122115 [code]
Midfrontal theta power relates to response speeding following frustrative nonreward.
Journal: NeuroImage
In common: car, lmerTest, lme4, 4 other tools, cognitive, 2 references
[3] doi:10.1016/j.nicl.2026.104012 [code]
Structural-functional multilayer brain network properties and outcome of combined repetitive transcranial magnetic stimulation and psychotherapy for obsessive-compulsive disorder.
Journal: NeuroImage. Clinical
In common: car, lmerTest, SPM, 5 other tools, fMRI, other condition
[4] doi:10.1162/imag.a.105 [code]
Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation
Journal: —
In common: car, lmerTest, SPM, 4 other tools, fMRI, cognitive, 1 reference
[5] doi:10.1093/braincomms/fcag121 [code]
Anterior insular co-activation patterns associated with stress markers in chronic primary pain.
Journal: Brain communications
In common: car, lmerTest, lme4, 5 other tools, fMRI
[6] doi:10.7554/elife.103846 [code]
Overt visual attention modulates decision-related signals in the frontal cortex.
Journal: eLife
In common: lmerTest, SPM, lme4, 3 other tools, cognitive, 2 references
[7] doi:10.1371/journal.pone.0353990 [code]
Positive mood enhances accessibility of unrelated concepts in the first language but not in the foreign language.
Journal: PloS one
In common: car, lmerTest, lme4, 4 other tools, cognitive, 1 reference
[8] doi:10.1016/j.isci.2026.116747 [code]
Age and loneliness relate to reduced trust learning and alterations in amygdala function.
Journal: iScience
In common: car, lmerTest, lme4, 3 other tools, fMRI, cognitive, 1 reference
[9] doi:10.1038/s41598-026-53424-4 [code]
Cognitive control networks causally support implicit emotion regulation: evidence from dlPFC stimulation and directed functional connectivity.
Journal: Scientific reports
In common: car, lmerTest, lme4, 3 other tools, cognitive, 2 references
[10] doi:10.1162/imag.a.1330 [code]
Human risk taking and metabolic state: No credible evidence for desacyl-ghrelin modulation of neural or behavioural effects.
Journal: Imaging neuroscience (Cambridge, Mass.)
In common: SPM, cowplot, reshape2, 2 other tools, fMRI, cognitive, 2 references

Contribute

The authors of this paper can claim it, correct its record and validate its tracing map, and the maintainers of its code (its owner, or a public member of its organization) correct what it says of their repository; anyone signed in can ask for its removal. Every request goes to OSCR's own machine, which answers it; your account page follows them.

Sign in with ORCID to claim this paper as one of its authors, correct its record or validate its tracing map: when the paper's metadata lists your ORCID iD, you are recognized at once. Maintainers of its code: sign in with GitHub, then claim the repository on your account page.

Request its removal

To ask OSCR to remove this record, the copies of its authors' scripts or its tracing map, use the removal request page: signed in, you say who you are, what to remove and why, then review and confirm the request. Published rules decide every request (how).

Discussion, reproductions, activity

Discussion: questions and error reports about this paper and its code, from signed-in readers and its authors. It opens with sign-in.

Reproductions: reports from readers who ran the authors' code: what they reproduced, with which environment, commit and data. It opens with sign-in.

Activity: what happens around this paper: new versions of its record, its map's validation, discussions and reproductions. It opens with sign-in.