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PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma.

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Authors: Ryan J Duchatel, Evangeline R Jackson, Sarah G Parackal, Dylan Kiltschewskij, Izac J Findlay, Abdul Mannan, Dilana E Staudt, Bryce C Thomas, Zacary P Germon, Sandra Laternser, Padraic S Kearney, M Fairuz B Jamaluddin, Alicia M Douglas, Tyrone Beitaki, Holly P McEwen, Mika L Persson, Emily A Hocke, Vaibhav Jain, Michael Aksu, Elizabeth E Manning
and 35 other authorsHeather C Murray, Nicole M Verrills, Claire Xin Sun, Paul Daniel, Ricardo E Vilain, David A Skerrett-Byrne, Brett Nixon, Susan Hua, Charles E de Bock, Yolanda Colino-Sanguino, Fatima Valdes-Mora, Maria Tsoli, David S Ziegler, Murray J Cairns, Eric H Raabe, Nicholas A Vitanza, Esther Hulleman, Timothy N Phoenix, Carl Koschmann, Frank Alvaro, Christopher V Dayas, Christopher L Tinkle, Helen Wheeler, James R Whittle, David D Eisenstat, Ron Firestein, Sabine Mueller, Santosh Valvi, Jordan R Hansford, David M Ashley, Simon G Gregory, Lindsay B Kilburn, Javad Nazarian, Jason E Cain, Matthew D Dun
Published: 6 February 2024
Type: Research article
License: CC BY
Institutions: Hunter Medical Research Institute (Australia), University of Newcastle Australia (Australia), Hudson Institute of Medical Research (Australia), Monash University (Australia), University Children's Hospital Zurich (Switzerland), Duke University (United States), Duke Medical Center (United States), UNSW Sydney (Australia), Sydney Children's Hospital (Australia), Johns Hopkins University (United States), Johns Hopkins Medicine (United States), Seattle Children's Hospital (United States), University of Washington (United States), Seattle Children's Research Institute (United States), Princess Máxima Center (Netherlands), University of Cincinnati (United States), University of Michigan (United States), Michigan Medicine (United States), John Hunter Children's Hospital (Australia), St. Jude Children's Research Hospital (United States), The University of Sydney (Australia), Royal North Shore Hospital (Australia), The University of Melbourne (Australia), Walter and Eliza Hall Institute of Medical Research (Australia), Peter MacCallum Cancer Centre (Australia), Royal Children's Hospital (Australia), Murdoch Children's Research Institute (Australia), University of California, San Francisco (United States), The Kids Research Institute Australia (Australia), The University of Western Australia (Australia), Princess Margaret Hospital for Children (Australia), Perth Children's Hospital (Australia), Women's and Children's Hospital (Australia), South Australian Health and Medical Research Institute (Australia), The University of Adelaide (Australia), Children's National (United States), George Washington University (United States)

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