Proteomic profiling reveals structural and adhesion pathways regulated by the inverted CHRFAM7AΔ2bp variant in human neural progenitor cells.

Overview

Authors: Natalie Erickson¹, Ivanna Ihnatovych², Andras Szabados², Kinga Szigeti², Nadine Kabbani^1,3

Interdisciplinary Program in Neuroscience, George Mason University,4400 University Drive, Fairfax, VA 22030 USA
Department of Neurology, State University of New York at Buffalo,875 Ellicott St, Buffalo, NY 14203 USA
School of Systems Biology, George Mason University,4400 University Drive, Fairfax, VA 22030 USA

Institutions: George Mason University (United States); State University of New York (United States)

Journal: BMC neuroscience, volume 27, issue 1, article 31

Dates: received 13 January 2026; accepted 5 June 2026; published online 13 June 2026

Type: Research article · Language: English

License: CC BY-NC-ND

Identifiers: DOI 10.1186/s12868-026-01016-3 · PMID 42288732 · PMCID PMC13491803 · OpenAlex W7164675978

Open access: gold, a free copy (OpenAlex)

Status: data only

Categories: genetics / omics (modality), human (organism), developmental (subfield)

Methods: Statistics

Keywords: CHRFAM7AΔ2bp, Adhesion, ECM interaction, Neurodevelopment

MeSH: alpha7 Nicotinic Acetylcholine Receptor*, Induced Pluripotent Stem Cells*, Neural Stem Cells*, Cell Adhesion, Cell Differentiation, Cell Line, Humans, Proteomics (* major topic)

Topic: Nicotinic Acetylcholine Receptors Study (Molecular Biology, Biochemistry, Genetics and Molecular Biology), according to OpenAlex

Citations: not cited yet (Europe PMC); 49 references in the paper

Abstract

The abstract is not reproduced here: the paper's license (CC BY-NC-ND) does not allow it. Read it in the paper, at the publisher or on Europe PMC.

Code

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Data

Datasets cited

figshare:32034915, at figshare; found in “Data availability”

Data availability statement

The paper has a data availability statement. Its license (CC BY-NC-ND) does not allow reproducing it here; in short, from what the harvester recognized in it:

it points to a dataset: figshare 32034915

Read it in the paper: doi.org/10.1186/s12868-026-01016-3.

Versions

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Version 1, 27 September 2026: the first record

Recorded: type, language, journal, volume, issue, pages, dates, 5 authors, 4 keywords, 8 MeSH terms, 49 references.

Cite

This paper

Erickson, N., Ihnatovych, I., Szabados, A., Szigeti, K., & Kabbani, N. (2026). Proteomic profiling reveals structural and adhesion pathways regulated by the inverted CHRFAM7AΔ2bp variant in human neural progenitor cells. BMC neuroscience, 27(1), 31. https://doi.org/10.1186/s12868-026-01016-3

BibTeX

@article{erickson2026proteomic, author = {Erickson, Natalie and Ihnatovych, Ivanna and Szabados, Andras and Szigeti, Kinga and Kabbani, Nadine}, title = {{Proteomic profiling reveals structural and adhesion pathways regulated by the inverted CHRFAM7AΔ2bp variant in human neural progenitor cells}}, journal = {BMC neuroscience}, year = {2026}, month = jun, volume = {27}, number = {1}, pages = {31}, publisher = {BMC}, issn = {1471-2202}, doi = {10.1186/s12868-026-01016-3}, url = {https://doi.org/10.1186/s12868-026-01016-3}, pmid = {42288732}, pmcid = {PMC13491803} }

RIS

TY - JOUR AU - Erickson, Natalie AU - Ihnatovych, Ivanna AU - Szabados, Andras AU - Szigeti, Kinga AU - Kabbani, Nadine TI - Proteomic profiling reveals structural and adhesion pathways regulated by the inverted CHRFAM7AΔ2bp variant in human neural progenitor cells T2 - BMC neuroscience J2 - BMC Neurosci PY - 2026 DA - 2026/06/13 VL - 27 IS - 1 SP - 31 SN - 1471-2202 PB - BMC DO - 10.1186/s12868-026-01016-3 UR - https://doi.org/10.1186/s12868-026-01016-3 LA - en ER -

CSL-JSON

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